The antioxidant properties of galloyl quinic derivatives isolated from Pistacia lentiscus L. leaves have been investigated by means of Electron Paramagnetic Resonance spectroscopy (EPR) and UV-Vis spectrophotometry. Antioxidant properties have been also estimated using the biologically relevant LDL test. The scavenger activities of gallic acid, 5-O-galloyl, 3,5-O-digalloyl, 3,4,5-O-trigalloyl quinic acid derivatives, have been estimated against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, superoxide (O2-) radical, and hydroxyl (OH) radical. On the whole, the scavenger activity raised as the number of galloyl groups on the quinic acid skeleton increased. The half-inhibition concentrations (IC50) of di- and tri-galloyl derivatives did not exceed 30 mM for all the tested free radicals. All the tested metabolites strongly reduced the oxidation of low-density lipoproteins (LDL), following a trend similar to that observed for the scavenger ability against OH radical.
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|Titolo:||Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves|
|Rivista:||FREE RADICAL RESEARCH|
|Citazione:||Baratto, M.C., Tattini, M., Galardi, C., Pinelli, P., Romani, A., Visioli, F., et al. (2003). Antioxidant activity of galloyl quinic derivatives isolated from P. lentiscus leaves. FREE RADICAL RESEARCH, 37(4), 405-412.|
|Appare nelle tipologie:||1.1 Articolo in rivista|