Recent studies have shown the relevance of the cerebral grey matter involvement in multiple sclerosis (MS). Cortical lesions (CLs), detected by specific MRI sequences, are likely to become a new research outcome in MS studies. The aim of this study was to infer the optimal statistical model describing the distribution of CLs in patients with relapsing-remitting (RR)MS. The negative binomial model gave the best fit to the observed distribution of CLs in a group of 44 RRMS patients with one MRI scan of the brain. This observation has important implications for the statistical analysis of CLs in MS studies.
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|Titolo:||Modelling the distribution of cortical lesions in multiple sclerosis|
|Citazione:||Sormani, M., Stromillo, M.L., Battaglini, M., Signori, A., & DE STEFANO, N. (2012). Modelling the distribution of cortical lesions in multiple sclerosis. MULTIPLE SCLEROSIS, 18(2), 229-231.|
|Appare nelle tipologie:||1.1 Articolo in rivista|