Rosacea and chronic urticaria are two common skin disorders existing in idiopathic forms. A role of Helicobacter pylori bacterium infection in the aetiopathogenesis of rosacea or chronic urticaria has been suggested although still controversial. The aim of the present study was to establish a relationship between H. pylori infection and rosacea chronic urticaria by means of an immunoproteomic investigation. We analyzed immunoglobulin A (IgA)-, IgG-, and IgE-mediated immune-responses against H. pylori antigens and we identified some bacterial immunoresponsive proteins. A general IgA- and IgE-mediated immune response against antioxidative bacterial proteins was observed. A correlation between the bacterial occurrence and skin diseases pathogenesis is discussed.

Mini, R., Figura, N., D'Ambrosio, C., Braconi, D., Bernardini, G., DI SIMPLICIO, F., et al. (2005). Helicobacter pylori immunoproteomes in case reports of rosacea and chronic urticaria. PROTEOMICS, 5(3), 777-787 [10.1002/pmic.200401094].

Helicobacter pylori immunoproteomes in case reports of rosacea and chronic urticaria.

FIGURA, NATALE;BRACONI, DANIELA;BERNARDINI, GIULIA;NUTI, RANUCCIO;TRABALZINI, LORENZA;BOVALINI, LUCIA;SANTUCCI, ANNALISA
2005-01-01

Abstract

Rosacea and chronic urticaria are two common skin disorders existing in idiopathic forms. A role of Helicobacter pylori bacterium infection in the aetiopathogenesis of rosacea or chronic urticaria has been suggested although still controversial. The aim of the present study was to establish a relationship between H. pylori infection and rosacea chronic urticaria by means of an immunoproteomic investigation. We analyzed immunoglobulin A (IgA)-, IgG-, and IgE-mediated immune-responses against H. pylori antigens and we identified some bacterial immunoresponsive proteins. A general IgA- and IgE-mediated immune response against antioxidative bacterial proteins was observed. A correlation between the bacterial occurrence and skin diseases pathogenesis is discussed.
Mini, R., Figura, N., D'Ambrosio, C., Braconi, D., Bernardini, G., DI SIMPLICIO, F., et al. (2005). Helicobacter pylori immunoproteomes in case reports of rosacea and chronic urticaria. PROTEOMICS, 5(3), 777-787 [10.1002/pmic.200401094].
File in questo prodotto:
File Dimensione Formato  
2005_Proteomics.pdf

non disponibili

Tipologia: Post-print
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 663.3 kB
Formato Adobe PDF
663.3 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/21636
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo