Using a syringe-like device, Shigella delivers an array of virulence factors into host cells to facilitate bacterial colonization and disable the host's innate immune defense. In this issue of Cell Host & Microbe, Konradt and colleagues (Konradt et al., 2011) show that Shigella also subverts adaptive immunity by targeting T cells through a mechanism involving PIP2 breakdown.
Telford, J.L., Baldari, C. (2011). Shigella targets T cells. CELL HOST & MICROBE, 9(4), 253-254 [10.1016/j.chom.2011.04.003].
Shigella targets T cells
Baldari, Cosima
2011-01-01
Abstract
Using a syringe-like device, Shigella delivers an array of virulence factors into host cells to facilitate bacterial colonization and disable the host's innate immune defense. In this issue of Cell Host & Microbe, Konradt and colleagues (Konradt et al., 2011) show that Shigella also subverts adaptive immunity by targeting T cells through a mechanism involving PIP2 breakdown.File in questo prodotto:
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