Neisseria meningitidis infection still remains a major life-threatening bacterial disease worldwide. The availability of bacterial genomic sequences generated a paradigm shift in microbiological and vaccines sciences, and post-genomics (comparative genomics, functional genomics, proteomics and a combination/evolution of these techniques) played important roles in elucidating bacterial biological complexity and pathogenic traits, at the same time accelerating the development of therapeutic drugs and vaccines. This article summarizes the most recent technological and scientific advances in meningococcal biology and pathogenesis aimed at the development and characterization of vaccines against the pathogenic meningococci.

Bernardini, G., Braconi, D., Lusini, P., & Santucci, A. (2011). Post-genomics of Neisseria meningitidis: an update. EXPERT REVIEW OF PROTEOMICS, 8(6), 803-811 [10.1586/EPR.11.59].

Post-genomics of Neisseria meningitidis: an update

BERNARDINI, GIULIA;BRACONI, DANIELA;SANTUCCI, ANNALISA
2011

Abstract

Neisseria meningitidis infection still remains a major life-threatening bacterial disease worldwide. The availability of bacterial genomic sequences generated a paradigm shift in microbiological and vaccines sciences, and post-genomics (comparative genomics, functional genomics, proteomics and a combination/evolution of these techniques) played important roles in elucidating bacterial biological complexity and pathogenic traits, at the same time accelerating the development of therapeutic drugs and vaccines. This article summarizes the most recent technological and scientific advances in meningococcal biology and pathogenesis aimed at the development and characterization of vaccines against the pathogenic meningococci.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/21058
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