Cell-mediated cytotoxicities, such as natural killer (NK) and T-dependent cytotoxic (CTL) activities, are inhibited to the same extent by lysosomotropic amines, even when interferon is added to cultures to enhance lysis. It is postulated that the amines block steps common to spontaneous and IFN-enhanced NK and CTL lytic mechanisms.
Ausiello, C., Sorrentino, V., Ruggiero, V., Rossi, G.B. (1984). Action of lysosomotropic amines on spontaneous and interferon enhanced NK and CTL cytolysis. IMMUNOLOGY LETTERS, 8(1), 11-15 [10.1016/0165-2478(84)90097-X].
Action of lysosomotropic amines on spontaneous and interferon enhanced NK and CTL cytolysis
Sorrentino, V.;Rossi, G. B.
1984-01-01
Abstract
Cell-mediated cytotoxicities, such as natural killer (NK) and T-dependent cytotoxic (CTL) activities, are inhibited to the same extent by lysosomotropic amines, even when interferon is added to cultures to enhance lysis. It is postulated that the amines block steps common to spontaneous and IFN-enhanced NK and CTL lytic mechanisms.
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https://hdl.handle.net/11365/20837
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