Extended-spectrum beta-lactamases (ESBLs) belonging to the TEM and SHV families were investigated in 583 ESBL-producing Enterobacteriaceae collected at the clinical microbiology laboratories of 11 teaching Italian hospitals. By molecular analysis TEM-type and SHV-type ESBLs were confirmed on 154 and 74 isolates, respectively. High variability was found among TEM-types beta-lactamases with the following variants: TEM-5, TEM-6, TEM-12, TEM-15, TEM-24, TEM-26, TEM-29, TEM-52, TEM-92, TEM-134, and TEM-149. Among SHV variants, SHV-2a, SHV-5, SHV-12, and SHV-28 have been detected. The most widespread variants are TEM-52/92 and SHV-12.
Perilli, M., Segatore, B., Mugnaioli, C., Celenza, G., Rossolini, G.M., Stefani, S., et al. (2011). Persistence of TEM-52/TEM-92 and SHV-12 Extended-Spectrum ß-Lactamases in Clinical Isolates of Enterobacteriaceae in Italy. MICROBIAL DRUG RESISTANCE, 17(4), 521-524 [10.1089/mdr.2011.0059].
Persistence of TEM-52/TEM-92 and SHV-12 Extended-Spectrum ß-Lactamases in Clinical Isolates of Enterobacteriaceae in Italy
ROSSOLINI G. M.;
2011-01-01
Abstract
Extended-spectrum beta-lactamases (ESBLs) belonging to the TEM and SHV families were investigated in 583 ESBL-producing Enterobacteriaceae collected at the clinical microbiology laboratories of 11 teaching Italian hospitals. By molecular analysis TEM-type and SHV-type ESBLs were confirmed on 154 and 74 isolates, respectively. High variability was found among TEM-types beta-lactamases with the following variants: TEM-5, TEM-6, TEM-12, TEM-15, TEM-24, TEM-26, TEM-29, TEM-52, TEM-92, TEM-134, and TEM-149. Among SHV variants, SHV-2a, SHV-5, SHV-12, and SHV-28 have been detected. The most widespread variants are TEM-52/92 and SHV-12.
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https://hdl.handle.net/11365/20127
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