SUMMARY: Morphometry and spectroscopy were performed in 3 patients with fragile X-associated tremor/ataxia syndrome (FXTAS). The brain stem and cerebellum were atrophic and satisfied criteria for olivopontocerebellar atrophy in 2 patients. However, the vermis was relatively spared and the basis pontis maintained its oval shape. The only spectroscopic abnormality was a decrease of the pontine N-acetylaspartate/creatine ratio in 1 patient. Atrophy and metabolic changes in FXTAS differ to some extent from those of olivopontocerebellar atrophy.

Ginestroni, A., Guerrini, L., DELLA NAVE, R., Tessa, C., Cellini, E., Dotti, M., et al. (2007). Morphometry and 1H- MR spectroscopy of the brainstem and cerebellum in three patients with fragile X-associated tremor/ataxia syndrome (FXTAS). AJNR, AMERICAN JOURNAL OF NEURORADIOLOGY, 28(3), 486-488.

Morphometry and 1H- MR spectroscopy of the brainstem and cerebellum in three patients with fragile X-associated tremor/ataxia syndrome (FXTAS).

DOTTI, MARIA;DE STEFANO, NICOLA;
2007-01-01

Abstract

SUMMARY: Morphometry and spectroscopy were performed in 3 patients with fragile X-associated tremor/ataxia syndrome (FXTAS). The brain stem and cerebellum were atrophic and satisfied criteria for olivopontocerebellar atrophy in 2 patients. However, the vermis was relatively spared and the basis pontis maintained its oval shape. The only spectroscopic abnormality was a decrease of the pontine N-acetylaspartate/creatine ratio in 1 patient. Atrophy and metabolic changes in FXTAS differ to some extent from those of olivopontocerebellar atrophy.
2007
Ginestroni, A., Guerrini, L., DELLA NAVE, R., Tessa, C., Cellini, E., Dotti, M., et al. (2007). Morphometry and 1H- MR spectroscopy of the brainstem and cerebellum in three patients with fragile X-associated tremor/ataxia syndrome (FXTAS). AJNR, AMERICAN JOURNAL OF NEURORADIOLOGY, 28(3), 486-488.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/20074
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