This paper explores physical signalling in biological communications, the so-called biophysical pathways, and especially the role of electromagnetic signalling in cell-cell interactions. The experiments were designed to evaluate whether different cell populations physically interfere when incubated in separate Petri dishes placed in close proximity. Two different cell populations, immortalized mouse fibroblasts (NIH3T3) and adult human microvascular endothelial cells (HMVECad) were selected and seeded in separate polystyrene Petri dishes. Dishes seeded with NIH3T3 were then placed on top of those seeded with HMVECad at distances of 4 mm and 11 mm. A black filter was placed between dishes containing the two cell populations in another experiment, to prevent transmission of electromagnetic radiation between the two. Cell number and morphology of NIH3T3 and endothelial cells were found to be modified in dishes without the black filter, suggesting that specific signals emitted by the cells were transmitted through the polystyrene wall, affecting cell proliferation rate and morphology, even though the cells were growing in separate dishes.
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|Titolo:||New perspectives in cell communication: Bioelectromagnetic interactions|
|Citazione:||New perspectives in cell communication: Bioelectromagnetic interactions / Rossi, Claudio; Foletti, A; Magnani, Agnese; Lamponi, Stefania. - ELETTRONICO. - 21:3(2011), pp. 207-214.|
|Appare nelle tipologie:||1.1 Articolo in rivista|