In a very remote rural Bolivian community where the use of antimicrobials has been minimal and where exchanges with the exterior are very limited, 67% of subjects were found to be carriers of fecal Escherichia coli with acquired resistance to greater than or equal to1 antimicrobial agent(s); the highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these findings is that, in certain settings, the spread and maintenance of antimicrobial resistance can occur, regardless of whether selective pressure generated by the use of antimicrobials is present.
Bartoloni, A., Bartalesi, F., Mantella, A., Dell'Amico, E., Roselli, M., Strohmeyer, M., et al. (2004). High prevalence of antimicrobial resistance unrelated to heavy antimicrobial consumption. THE JOURNAL OF INFECTIOUS DISEASES, 189(7), 1291-1294 [10.1086/382191].
High prevalence of antimicrobial resistance unrelated to heavy antimicrobial consumption
ROSSOLINI G. M.
2004-01-01
Abstract
In a very remote rural Bolivian community where the use of antimicrobials has been minimal and where exchanges with the exterior are very limited, 67% of subjects were found to be carriers of fecal Escherichia coli with acquired resistance to greater than or equal to1 antimicrobial agent(s); the highest rates were observed for tetracycline (64%), ampicillin (58%), trimethoprim-sulfamethoxazole (50%), and chloramphenicol (41%). The most relevant implication of these findings is that, in certain settings, the spread and maintenance of antimicrobial resistance can occur, regardless of whether selective pressure generated by the use of antimicrobials is present.File | Dimensione | Formato | |
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https://hdl.handle.net/11365/18125
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