Management of a rare ulcerated erythema nodosum in a patient affected by Crohn's disease and tuberculosis

We reported a rare case of Erythema Nodosum secondary to Crohn's disease in which nodes localized to lower limbs became ulcerated even if usually they spontaneously involves in few weeks. After the patient contracted tuberculosis, that is another factor favouring secondary EN, immunomodulating therapy had been reduced to avoid the spreading of the infection: in this way panniculitides had became quiet untreatable. Skin ulcers underlying lower limbs nodularities had appeared and different strategies of treatment failed being no longer sufficient to reach adequate healing. We emphasize the use of cycles of VAC therapy alternated to Promogran© as valid approach providing a means of achieving a good healing.