Deep Learning for Risky Cardiovascular and Cerebrovascular Event Prediction in Hypertensive Patients

In this comprehensive study, we employed a versatile approach to tackle the prediction challenges associated with atrial fibrillation (AF) and cardiovascular events (CE). Exploiting the Gaussian copula synthesizer technique for data generation, we created high-quality synthetic data to overcome the limitations posed by scarce patient records. Heart rate variability (HRV), known to be an efficient indicator of cardiac health often used with artificial intelligence (AI), was used to train and optimize custom-built deep learning (DL) models. Additionally, we explored transfer learning (TL) to enhance the model capabilities by adapting our AF classification model to address CE classification challenges, effectively transferring learned features and patterns, without extensive retraining. As a result, our models achieved accuracy rates of 77% for AF and 82% for CEs, with high sensitivity, highlighting the efficacy of synthetic data generation and transfer learning in improving classification performance across diverse medical datasets. These findings hold significant promise for enhancing diagnostic and predictive capabilities in clinical settings, ultimately contributing to improved patient care and outcomes. © 2025 by the authors.