A Five Hundred Six-Gram Giant Orbital Retinoblastoma: An Unusual Case Report

We present the case of a 14-month-old Caucasian male with advanced orbital retinoblastoma. The patient, having undergone enucleation elsewhere for intraocular retinoblastoma without adjuvant therapy, developed a massive fungating orbital mass shortly after surgery. De- spite orbital exenteration and subsequent systemic therapy, the tumor recurred rapidly, leading to systemic metastases and eventual demise. We describe the clinical and diagnostical workup of this rare disease done in a developed country, which given the rarity of this condition in this kind of setting, highlights the importance of education about a prompt approach to avoid the consequences related to a delayed intervention.