Inflammatory cytokines and cardiac arrhythmias: the lesson from COVID-19

COVID-19 is associated with an unexpectedly high prevalence of arrhythmic events. In this Comment, Lazzerini et al. discuss how systemic inflammation is linked to cardiac arrhythmias.Although inflammatory cytokines are implicated in the pathogenesis of cardiac arrhythmias, inflammation is still largely overlooked in the current management of heart rhythm disorders. Now, COVID-19, a systemic inflammatory disease, causes an unexpectedly high prevalence of arrhythmic events, emphasizing the relevance of inflammation in the pathogenesis of cardiac arrhythmias.