The efficacy of a product containing hyaluronic acid and chondroitin sulphates was tested in a double-blind study versus placebo in 30 patients with psoriasic onychodystrophy. The patients were divided into two groups of 15 patients treated with the product and placebo respectively. An improvement with respect to controls was noted in patients using the product. The differences were significant for onychorrexis, onycholysis and subungueal hyperkeratosis. The results may be due to the hydrophilic property of hyaluronic acid and chondroitin sulphates, or perhaps even a direct effect on nail growth.
Flori, M.L., Rubegni, P., Micheli, S., Andreassi, L. (1994). Treatment of psoriasic onychodystrophy with a hyaluronic acid product and chondroitinsulphates. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, 129(3), 129-133.
Treatment of psoriasic onychodystrophy with a hyaluronic acid product and chondroitinsulphates
Flori M. L.;Rubegni P.;
1994-01-01
Abstract
The efficacy of a product containing hyaluronic acid and chondroitin sulphates was tested in a double-blind study versus placebo in 30 patients with psoriasic onychodystrophy. The patients were divided into two groups of 15 patients treated with the product and placebo respectively. An improvement with respect to controls was noted in patients using the product. The differences were significant for onychorrexis, onycholysis and subungueal hyperkeratosis. The results may be due to the hydrophilic property of hyaluronic acid and chondroitin sulphates, or perhaps even a direct effect on nail growth.
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https://hdl.handle.net/11365/1278344
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