12-Month Time in Tight Range Improvement with Advanced Hybrid-Closed Loop System in Adults with Type 1 Diabetes

IntroductionTime in tight range (TITR) is an emerging and valuable metric for assessing normoglycemia. The latest advancement in automated insulin delivery (AID) systems, the advanced hybrid closed-loop (AHCL) systems, are particularly noteworthy for managing type 1 diabetes (T1D) and enhancing glycemic control.MethodsIn a real-world clinical setting, we carried out a retrospective evaluation of TITR in 42 adult subjects with T1D using the AHCL Minimed (TM) 780G system over a 12-month period.ResultsWithin just 14 days of activating the automatic mode, the AHCL Minimed (TM) 780G system showed rapid improvement in TITR, and in the other continuous glucose monitoring (CGM) metrics. This improvement persisted over 12 months, achieving the proposed 45-50% range for effective glycemic control.ConclusionThe AHCL Minimed (TM) 780G system significantly enhances TITR, demonstrating continuous improvement throughout a 12-month follow-up period.