An amidic derivative of a carboxymethylcellulose-based hydrogel was obtained and characterized in terms of amidation degree. NMR studies and FT-IR imaging spectroscopy demonstrated that the reaction allowed a polymer to be obtained that was characterized by a regular distribution of amidic groups along the polysaccharide chains. Through this regularity, a homogenous three-dimensional scaffold was obtained, which maintained the thixotropic property of the linear polysaccharide.

Leone, G., Maurizio, D., MARIA ENRICA DI, C., Anna, B., & Barbucci, R. (2008). The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: Structural and Rheological Characterisation. CARBOHYDRATE RESEARCH, 343, 317-327 [10.1016/j.carres.2007.10.017].

The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: Structural and Rheological Characterisation

LEONE, GEMMA;BARBUCCI, ROLANDO
2008

Abstract

An amidic derivative of a carboxymethylcellulose-based hydrogel was obtained and characterized in terms of amidation degree. NMR studies and FT-IR imaging spectroscopy demonstrated that the reaction allowed a polymer to be obtained that was characterized by a regular distribution of amidic groups along the polysaccharide chains. Through this regularity, a homogenous three-dimensional scaffold was obtained, which maintained the thixotropic property of the linear polysaccharide.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/12371
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