Attenzione: i dati modificati non sono ancora stati salvati. Per confermare inserimenti o cancellazioni di voci è necessario confermare con il tasto SALVA/INSERISCI in fondo alla pagina
IRIS
Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar inso-lation at the onset location was associated with the polarity of the first episode of BD I. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area of the Earth. Methods: Data from 7488 patients with BD I were collected at 75 sites in 42 countries. The first episode occurred at 591 onset locations in 67 countries at a wide range of latitudes in both hemispheres. Solar insolation values were obtained for every onset location, and the ratio of the minimum mean monthly insolation to the maximum mean monthly insolation was calculated. This ratio is largest near the equator (with little change in solar insolation over the year), and smallest near the poles (where winter insolation is very small compared to summer insolation). This ratio also applies to tropical locations which may have a cloudy wet and clear dry season, rather than winter and summer. Results: The larger the change in solar insolation throughout the year (smaller the ratio between the minimum monthly and maximum monthly values), the greater the likelihood the first episode polarity was depression. Other associated variables were being female and increasing percentage of gross domestic product spent on country health expenditures. (All coefficients: P <= 0.001). Conclusion: Increased awareness and research into circadian dysfunction throughout the course of BD is warranted.
Bauer, M., Glenn, T., Achtyes, E.D., Alda, M., Agaoglu, E., Altınbaş, K., et al. (2022). Association between polarity of first episode and solar insolation in bipolar I disorder. JOURNAL OF PSYCHOSOMATIC RESEARCH, 160, 110982 [10.1016/j.jpsychores.2022.110982].
Association between polarity of first episode and solar insolation in bipolar I disorder
Bauer, Michael;Glenn, Tasha;Achtyes, Eric D;Alda, Martin;Agaoglu, Esen;Altınbaş, Kürşat;Andreassen, Ole A;Angelopoulos, Elias;Ardau, Raffaella;Aydin, Memduha;Ayhan, Yavuz;Baethge, Christopher;Bauer, Rita;Baune, Bernhard T;Balaban, Ceylan;Becerra-Palars, Claudia;Behere, Aniruddh P;Behere, Prakash B;Belete, Habte;Belete, Tilahun;Belizario, Gabriel Okawa;Bellivier, Frank;Belmaker, Robert H;Benedetti, Francesco;Berk, Michael;Bersudsky, Yuly;Bicakci, Şule;Birabwa-Oketcho, Harriet;Bjella, Thomas D;Brady, Conan;Cabrera, Jorge;Cappucciati, Marco;Castro, Angela Marianne Paredes;Chen, Wei-Ling;Cheung, Eric Y W;Chiesa, Silvia;Crowe, Marie;Cuomo, Alessandro;Dallaspezia, Sara;Del Zompo, Maria;Desai, Pratikkumar;Dodd, Seetal;Etain, Bruno;Fagiolini, Andrea;Fellendorf, Frederike T;Ferensztajn-Rochowiak, Ewa;Fiedorowicz, Jess G;Fountoulakis, Kostas N;Frye, Mark A;Geoffroy, Pierre A;Gonzalez-Pinto, Ana;Gottlieb, John F;Grof, Paul;Haarman, Bartholomeus C M;Harima, Hirohiko;Hasse-Sousa, Mathias;Henry, Chantal;Høffding, Lone;Houenou, Josselin;Imbesi, Massimiliano;Isometsä, Erkki T;Ivkovic, Maja;Janno, Sven;Johnsen, Simon;Kapczinski, Flávio;Karakatsoulis, Gregory N;Kardell, Mathias;Kessing, Lars Vedel;Kim, Seong Jae;König, Barbara;Kot, Timur L;Koval, Michael;Kunz, Mauricio;Lafer, Beny;Landén, Mikael;Larsen, Erik R;Lenger, Melanie;Lewitzka, Ute;Licht, Rasmus W;Lopez-Jaramillo, Carlos;MacKenzie, Alan;Madsen, Helle Østergaard;Madsen, Simone Alberte Kongstad A;Mahadevan, Jayant;Mahardika, Agustine;Manchia, Mirko;Marsh, Wendy;Martinez-Cengotitabengoa, Monica;Martiny, Klaus;Mashima, Yuki;McLoughlin, Declan M;Meesters, Ybe;Melle, Ingrid;Meza-Urzúa, Fátima;Mok, Yee Ming;Monteith, Scott;Moorthy, Muthukumaran;Morken, Gunnar;Mosca, Enrica;Mozzhegorov, Anton A;Munoz, Rodrigo;Mythri, Starlin V;Nacef, Fethi;Nadella, Ravi K;Nakanotani, Takako;Nielsen, René Ernst;O'Donovan, Claire;Omrani, Adel;Osher, Yamima;Ouali, Uta;Pantovic-Stefanovic, Maja;Pariwatcharakul, Pornjira;Petite, Joanne;Pfennig, Andrea;Ruiz, Yolanda Pica;Pinna, Marco;Pompili, Maurizio;Porter, Richard;Quiroz, Danilo;Rabelo-da-Ponte, Francisco Diego;Ramesar, Raj;Rasgon, Natalie;Ratta-Apha, Woraphat;Ratzenhofer, Michaela;Redahan, Maria;Reddy, M S;Reif, Andreas;Reininghaus, Eva Z;Richards, Jenny Gringer;Ritter, Philipp;Rybakowski, Janusz K;Sathyaputri, Leela;Scippa, Ângela M;Simhandl, Christian;Smith, Daniel;Smith, José;Stackhouse, Paul W;Stein, Dan J;Stilwell, Kellen;Strejilevich, Sergio;Su, Kuan-Pin;Subramaniam, Mythily;Sulaiman, Ahmad Hatim;Suominen, Kirsi;Tanra, Andi J;Tatebayashi, Yoshitaka;Teh, Wen Lin;Tondo, Leonardo;Torrent, Carla;Tuinstra, Daniel;Uchida, Takahito;Vaaler, Arne E;Vieta, Eduard;Viswanath, Biju;Yoldi-Negrete, Maria;Yalcinkaya, Oguz Kaan;Young, Allan H;Zgueb, Yosra;Whybrow, Peter C
2022-01-01
Abstract
Objective: Circadian rhythm disruption is commonly observed in bipolar disorder (BD). Daylight is the most powerful signal to entrain the human circadian clock system. This exploratory study investigated if solar inso-lation at the onset location was associated with the polarity of the first episode of BD I. Solar insolation is the amount of electromagnetic energy from the Sun striking a surface area of the Earth. Methods: Data from 7488 patients with BD I were collected at 75 sites in 42 countries. The first episode occurred at 591 onset locations in 67 countries at a wide range of latitudes in both hemispheres. Solar insolation values were obtained for every onset location, and the ratio of the minimum mean monthly insolation to the maximum mean monthly insolation was calculated. This ratio is largest near the equator (with little change in solar insolation over the year), and smallest near the poles (where winter insolation is very small compared to summer insolation). This ratio also applies to tropical locations which may have a cloudy wet and clear dry season, rather than winter and summer. Results: The larger the change in solar insolation throughout the year (smaller the ratio between the minimum monthly and maximum monthly values), the greater the likelihood the first episode polarity was depression. Other associated variables were being female and increasing percentage of gross domestic product spent on country health expenditures. (All coefficients: P <= 0.001). Conclusion: Increased awareness and research into circadian dysfunction throughout the course of BD is warranted.
Bauer, M., Glenn, T., Achtyes, E.D., Alda, M., Agaoglu, E., Altınbaş, K., et al. (2022). Association between polarity of first episode and solar insolation in bipolar I disorder. JOURNAL OF PSYCHOSOMATIC RESEARCH, 160, 110982 [10.1016/j.jpsychores.2022.110982].
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1225705
Attenzione
Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo
Conferma cancellazione
Sei sicuro che questo prodotto debba essere cancellato?
simulazione ASN
Il report seguente simula gli indicatori relativi alla propria produzione scientifica in relazione alle soglie ASN 2023-2025 del proprio SC/SSD. Si ricorda che il superamento dei valori soglia (almeno 2 su 3) è requisito necessario ma non sufficiente al conseguimento dell'abilitazione. La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi di congedo obbligatorio, che in sede di domanda ASN danno diritto a incrementi percentuali dei valori. La simulazione può differire dall'esito di un’eventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, sia per la variabilità dei dati bibliometrici nel tempo. Si consideri che Anvur calcola i valori degli indicatori all'ultima data utile per la presentazione delle domande.
La presente simulazione è stata realizzata sulla base delle specifiche raccolte sul tavolo ER del Focus Group IRIS coordinato dall’Università di Modena e Reggio Emilia e delle regole riportate nel DM 589/2018 e allegata Tabella A. Cineca, l’Università di Modena e Reggio Emilia e il Focus Group IRIS non si assumono alcuna responsabilità in merito all’uso che il diretto interessato o terzi faranno della simulazione. Si specifica inoltre che la simulazione contiene calcoli effettuati con dati e algoritmi di pubblico dominio e deve quindi essere considerata come un mero ausilio al calcolo svolgibile manualmente o con strumenti equivalenti.