Background Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan. Aims The aims of this study were to: (1) determine the prevalence of frailty in an abdominal surgery setting independent of age; (2) evaluate the predictive validity of HGS for the length of hospital stay (LOS). Methods This is a retrospective study conducted in subjects who underwent abdominal surgical procedures. Only subjects with complete cognitive, functional, nutritional assessments and available measurement of HGS at admission were included. A final cohort of 108 patients were enrolled in the study. Results Subjects had a mean age of 67.8 +/- 15.8 years (age range 19-93 years old) and were mostly men. According to Fried's criteria, 17 (15.7%, 4F/13 M) were fit, 58 (23.7%; 24F/34 M) were pre-frail and 33 (30.6%; 20F/13 M) were frail. As expected, HGS significantly differed between groups having frail lower values as compared with pre-frail and fit persons (fit: 32.99 +/- 10.34 kg; pre-frail: 27.49 +/- 10.35 kg; frail: 15.96 +/- 9.52 kg, p < 0.0001). A final regression analysis showed that HGS was significantly and inversely associated with LOS (p = 0.020) independent of multiple covariates, including age. Discussion Most of the population undergoing abdominal surgery is pre-frail or frail. The measurement of handgrip strength is simple and inexpensive, and provides prognostic information for surgical outcomes. Muscle strength, as measured by handgrip dynamometry, is a strong predictor of LOS in a surgical setting.

Marano, L., Carbone, L., Poto, G.E., Gambelli, M., Nguefack Noudem, L.L., Grassi, G., et al. (2022). Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age. AGING CLINICAL AND EXPERIMENTAL RESEARCH, 34(4), 811-817 [10.1007/s40520-022-02121-z].

Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age

Marano, Luigi;Carbone, Ludovico;Poto, Gianmario Edoardo;Gambelli, Margherita;Nguefack Noudem, Leonelle Lore;Grassi, Giulia;Manasci, Fabiana;Curreri, Giulia;Giuliani, Alessandra;Piagnerelli, Riccardo;Savelli, Vinno;Marrelli, Daniele;Roviello, Franco;
2022-01-01

Abstract

Background Chronological age per se cannot be considered a prognostic risk factor for outcomes after elective surgery, whereas frailty could be. A simple and easy-to-get marker for frailty, such as handgrip strength (HGS), may support the surgeon in decision for an adequate healthcare plan. Aims The aims of this study were to: (1) determine the prevalence of frailty in an abdominal surgery setting independent of age; (2) evaluate the predictive validity of HGS for the length of hospital stay (LOS). Methods This is a retrospective study conducted in subjects who underwent abdominal surgical procedures. Only subjects with complete cognitive, functional, nutritional assessments and available measurement of HGS at admission were included. A final cohort of 108 patients were enrolled in the study. Results Subjects had a mean age of 67.8 +/- 15.8 years (age range 19-93 years old) and were mostly men. According to Fried's criteria, 17 (15.7%, 4F/13 M) were fit, 58 (23.7%; 24F/34 M) were pre-frail and 33 (30.6%; 20F/13 M) were frail. As expected, HGS significantly differed between groups having frail lower values as compared with pre-frail and fit persons (fit: 32.99 +/- 10.34 kg; pre-frail: 27.49 +/- 10.35 kg; frail: 15.96 +/- 9.52 kg, p < 0.0001). A final regression analysis showed that HGS was significantly and inversely associated with LOS (p = 0.020) independent of multiple covariates, including age. Discussion Most of the population undergoing abdominal surgery is pre-frail or frail. The measurement of handgrip strength is simple and inexpensive, and provides prognostic information for surgical outcomes. Muscle strength, as measured by handgrip dynamometry, is a strong predictor of LOS in a surgical setting.
2022
Marano, L., Carbone, L., Poto, G.E., Gambelli, M., Nguefack Noudem, L.L., Grassi, G., et al. (2022). Handgrip strength predicts length of hospital stay in an abdominal surgical setting: the role of frailty beyond age. AGING CLINICAL AND EXPERIMENTAL RESEARCH, 34(4), 811-817 [10.1007/s40520-022-02121-z].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1220599