Host T-cell response to Helicobacter pylori is important for the clinical outcome of the infection. A Th1-polarized response, preferentially against Ca-A. is associated with peptic ulcer, whereas mixed Th1 and Th0 responses are present in non-ulcer gastritis. A deregulated H. pylori-driven Th0 cell-dependent B-cell activation is found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
D'Elios, M.M., Amedei, A., Del Prete, G. (2003). Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma. MICROBES AND INFECTION, 5(8), 723-730 [10.1016/S1286-4579(03)00114-X].
Helicobacter pylori antigen-specific T-cell responses at gastric level in chronic gastritis, peptic ulcer, gastric cancer and low-grade mucosa-associated lymphoid tissue (MALT) lymphoma
D'Elios, M. M.;
2003-01-01
Abstract
Host T-cell response to Helicobacter pylori is important for the clinical outcome of the infection. A Th1-polarized response, preferentially against Ca-A. is associated with peptic ulcer, whereas mixed Th1 and Th0 responses are present in non-ulcer gastritis. A deregulated H. pylori-driven Th0 cell-dependent B-cell activation is found in low-grade B-cell lymphoma of mucosa-associated lymphoid tissue. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.File | Dimensione | Formato | |
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https://hdl.handle.net/11365/1220566