Clinical trials have demonstrated non-inferior viral suppression rates of selected 2-drug regimens (2DR) over standard 3-drug regimens (3DR). However, the impact of simplification to 2DR on HIV-1 reservoir remains to be fully assessed.
Dragoni, F., Rossetti, B., Lombardi, F., Raffaelli, C.S., Bartolini, N., Giammarino, F., et al. (2022). Dynamics of total and intact HIV-1 DNA in virologically suppressed patients switching to DTG- or ATV-based dual therapy. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Publish Ahead of Print [10.1097/QAI.0000000000003073].
Dynamics of total and intact HIV-1 DNA in virologically suppressed patients switching to DTG- or ATV-based dual therapy
Dragoni, Filippo;Rossetti, Barbara;Raffaelli, Chiara Spertilli;Bartolini, Niccolò;Giammarino, Federica;Fabbiani, Massimiliano;De Luca, Andrea;Vicenti, Ilaria;Zazzi, Maurizio;Saladini, Francesco
2022-01-01
Abstract
Clinical trials have demonstrated non-inferior viral suppression rates of selected 2-drug regimens (2DR) over standard 3-drug regimens (3DR). However, the impact of simplification to 2DR on HIV-1 reservoir remains to be fully assessed.
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https://hdl.handle.net/11365/1215195
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