Densitometric detection of compounds separated by thin layer was applied to the assay of a mixture of reserpine and chlorthalidone and their possible impurities. The method of analysis gave satisfactory results in the quality control of pharmaceutical preparations. Good results were obtained in urine tests for the detection of chlorthalidone, reserpine and methylreserpate. The times for the development of fluorescence in reserpine and methyl reserpate directly in the chromatographic plate, are also described.
Corti, P., Corbini, G., Dreassi, E., Murratzu, C., Celesti, L. (1990). Thin layer densitometry in the quantitative assay of drugs. Note V - Assay of the reserpine and chlorthalidone in the presence of the potential impurities of their solid pharmaceutical forms. PHARMACEUTICA ACTA HELVETIAE, 65(8), 222-227.
Thin layer densitometry in the quantitative assay of drugs. Note V - Assay of the reserpine and chlorthalidone in the presence of the potential impurities of their solid pharmaceutical forms
Corti P.;Corbini G.;Dreassi E.;
1990-01-01
Abstract
Densitometric detection of compounds separated by thin layer was applied to the assay of a mixture of reserpine and chlorthalidone and their possible impurities. The method of analysis gave satisfactory results in the quality control of pharmaceutical preparations. Good results were obtained in urine tests for the detection of chlorthalidone, reserpine and methylreserpate. The times for the development of fluorescence in reserpine and methyl reserpate directly in the chromatographic plate, are also described.
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https://hdl.handle.net/11365/11972
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