Human malignant tumors are characterized by abnormal proliferation resulting from alterations in cell cycle-regulatory mechanisms. The regulatory pathways controlling cell cycle phases include several oncogenes and tumor suppressor genes that display a range of abnormalities with potential usefulness as markers of evolution or treatment response in ovarian cancer. This review summarizes the current knowledge about these aberrations in malignant tumors of the ovary. We sought to divide cell cycle-regulatory genes into four subgroups on the basis of their predominant role in a specific phase or during the transition between two phases of the cell cycle.
Scheda prodotto non validato
Scheda prodotto in fase di analisi da parte dello staff di validazione
|Titolo:||Cell cycle genes in ovarian cancer: steps toward earlier diagnosis and novel therapies.|
|Rivista:||CLINICAL CANCER RESEARCH|
|Citazione:||D'Andrilli, G., Kumar, C., Scambia, G., & Giordano, A. (2004). Cell cycle genes in ovarian cancer: steps toward earlier diagnosis and novel therapies. CLINICAL CANCER RESEARCH, 10(24), 8132-8141.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
File in questo prodotto: