We report a severe case of diffuse lamellar keratitis (DLK) following femtosecond laser-assisted in situ keratomileusis (femto-LASIK). A 25-year-old man was submitted to 150 kHz iFS® IntraLase-assisted LASIK in both eyes for compound myopic astigmatism. The day after surgery, clinical examination showed a diffuse whitish granular cell reaction particularly in the right eye. High-dose dexamethasone eyedrops with topical antibiotic and artificial tears were prescribed. Five days after surgery, a central corneal opacity with convergent striae was detected at biomicroscopy. The suspicion of DLK was confirmed. Additional therapy based on hyperosmolar ophthalmological solution, oral doxycycline, and topical 10% sodium citrate was prescribed. Treatment was continued and tapered for over 3 months. Improvement in corneal transparency were obtained 2 weeks after the systemic therapy had been started. Uncorrected visual acuity improved from 20/32 to 20/20 at 1-year follow-up. DLK represents an infrequent complication after femto-LASIK. It should resolve without sequelae if promptly diagnosed and treated, without necessity of corneal flap lifting. © 2018 The Author(s). Published by S. Karger AG, Basel.

Balestrazzi, A., Balestrazzi, A., Giannico, M.I., Michieletto, P., Balestrazzi, E. (2018). Diagnosis, clinical trend, and treatment of diffuse lamellar keratitis after femtosecond laser-assisted in situ keratomileusis: A case report. CASE REPORTS IN OPHTHALMOLOGY, 9(3), 457-464 [10.1159/000493338].

Diagnosis, clinical trend, and treatment of diffuse lamellar keratitis after femtosecond laser-assisted in situ keratomileusis: A case report

Balestrazzi, Angelo;
2018-01-01

Abstract

We report a severe case of diffuse lamellar keratitis (DLK) following femtosecond laser-assisted in situ keratomileusis (femto-LASIK). A 25-year-old man was submitted to 150 kHz iFS® IntraLase-assisted LASIK in both eyes for compound myopic astigmatism. The day after surgery, clinical examination showed a diffuse whitish granular cell reaction particularly in the right eye. High-dose dexamethasone eyedrops with topical antibiotic and artificial tears were prescribed. Five days after surgery, a central corneal opacity with convergent striae was detected at biomicroscopy. The suspicion of DLK was confirmed. Additional therapy based on hyperosmolar ophthalmological solution, oral doxycycline, and topical 10% sodium citrate was prescribed. Treatment was continued and tapered for over 3 months. Improvement in corneal transparency were obtained 2 weeks after the systemic therapy had been started. Uncorrected visual acuity improved from 20/32 to 20/20 at 1-year follow-up. DLK represents an infrequent complication after femto-LASIK. It should resolve without sequelae if promptly diagnosed and treated, without necessity of corneal flap lifting. © 2018 The Author(s). Published by S. Karger AG, Basel.
2018
Balestrazzi, A., Balestrazzi, A., Giannico, M.I., Michieletto, P., Balestrazzi, E. (2018). Diagnosis, clinical trend, and treatment of diffuse lamellar keratitis after femtosecond laser-assisted in situ keratomileusis: A case report. CASE REPORTS IN OPHTHALMOLOGY, 9(3), 457-464 [10.1159/000493338].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/1131086