The right management of both mitral and aortic disease can be challenging, especially in asymptomatic patients. The current guidelines recommend valve repair or replacement when symptoms arise or when there is an evident left ventricular dysfunction. However, deciding the optimal surgical timing can be very difficult, since the line between the absence of symptoms and being minimally symptomatic, especially in the elderly, is blurred. Another relevant issue regards the second surgical criterion: operating on a patient with a reduced left ventricular ejection fraction or with a dilated left ventricle might jeopardize the possibility of a fully reverse remodeling of the heart after surgery. In this scenario, the left atrium might play an important role. In particular, left atrial deformation might be a very useful tool to detect early ultrastructural alterations, and help or support guiding a patient-tailored treatment at an early stage, optimizing the outcome in the long term. © 2019 Wiley Periodicals, Inc.
Cameli, M., Sciaccaluga, C., Mandoli, G.E., D'Ascenzi, F., Tsioulpas, C., Mondillo, S. (2019). The role of the left atrial function in the surgical management of aortic and mitral valve disease. ECHOCARDIOGRAPHY, 36(8), 1559-1565 [10.1111/echo.14426].
The role of the left atrial function in the surgical management of aortic and mitral valve disease
Cameli M.;Sciaccaluga C.;Mandoli G. E.;D'Ascenzi F.;Tsioulpas C.;Mondillo S.
2019-01-01
Abstract
The right management of both mitral and aortic disease can be challenging, especially in asymptomatic patients. The current guidelines recommend valve repair or replacement when symptoms arise or when there is an evident left ventricular dysfunction. However, deciding the optimal surgical timing can be very difficult, since the line between the absence of symptoms and being minimally symptomatic, especially in the elderly, is blurred. Another relevant issue regards the second surgical criterion: operating on a patient with a reduced left ventricular ejection fraction or with a dilated left ventricle might jeopardize the possibility of a fully reverse remodeling of the heart after surgery. In this scenario, the left atrium might play an important role. In particular, left atrial deformation might be a very useful tool to detect early ultrastructural alterations, and help or support guiding a patient-tailored treatment at an early stage, optimizing the outcome in the long term. © 2019 Wiley Periodicals, Inc.File | Dimensione | Formato | |
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https://hdl.handle.net/11365/1112636