Objectives: Individuals at ultra‐high risk of psychosis often present concurrent affective symptoms (depression/anxiety). This study investigated whether modular cognitive‐behavioral therapy (CBT) targeting both ultra‐high risk and affective symptoms (a) reduced/delayed risk of a first psychotic episode at posttreatment and 14‐month follow‐up compared with a supportive intervention, (b) was more effective than control condition in producing remission on depression/anxiety. Methods: Fifty‐eight ultrahigh risk individuals were randomly assigned to CBT or control condition. CBT consisted of 30 sessions, including CBT for psychotic experiences and depression/anxiety. Results: In the CBT group, the cumulative number of participants who developed a first psychotic episode (n = 3, 10.34%) at follow‐up was lower than in the control group (n = 8, 27.60%; logrank χ2(1) = 3.68, p = .05). In the CBT group, a higher number of participants achieved remission than in control condition on affective symptoms at posttreatment/follow‐up. Conclusion: CBT can prevent psychosis risk and produce better outcomes on depression/anxiety than supportive intervention.
Pozza, A., Dèttore, D. (2020). Modular cognitive‐behavioral therapy for affective symptoms in young individuals at ultra‐high risk of first episode of psychosis: Randomized controlled trial. JOURNAL OF CLINICAL PSYCHOLOGY, 76(3), 392-405 [10.1002/jclp.22901].
Modular cognitive‐behavioral therapy for affective symptoms in young individuals at ultra‐high risk of first episode of psychosis: Randomized controlled trial.
Andrea Pozza
;
2020-01-01
Abstract
Objectives: Individuals at ultra‐high risk of psychosis often present concurrent affective symptoms (depression/anxiety). This study investigated whether modular cognitive‐behavioral therapy (CBT) targeting both ultra‐high risk and affective symptoms (a) reduced/delayed risk of a first psychotic episode at posttreatment and 14‐month follow‐up compared with a supportive intervention, (b) was more effective than control condition in producing remission on depression/anxiety. Methods: Fifty‐eight ultrahigh risk individuals were randomly assigned to CBT or control condition. CBT consisted of 30 sessions, including CBT for psychotic experiences and depression/anxiety. Results: In the CBT group, the cumulative number of participants who developed a first psychotic episode (n = 3, 10.34%) at follow‐up was lower than in the control group (n = 8, 27.60%; logrank χ2(1) = 3.68, p = .05). In the CBT group, a higher number of participants achieved remission than in control condition on affective symptoms at posttreatment/follow‐up. Conclusion: CBT can prevent psychosis risk and produce better outcomes on depression/anxiety than supportive intervention.File | Dimensione | Formato | |
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https://hdl.handle.net/11365/1105038