M cells are higly specialized cells within the follicle-associated epithelium (FAE) of the respiratory and intestinal tracts. They play a central role in the induction of the mucosal immune response by transporting antigens to the lymphoid tissue. In this way the immune system may encounter the limitless variety of antigens that enter the body through the gut and airways. Here we describe the structure and the function of intestinal M cells. In addition, controversial issues relating to the M cell biology, such as APC function and the origin of M cells within the FAE, are discussed.
Borghesi, C., Regoli, M., Bertelli, E., Nicoletti, C. (1996). M cell: the main entrance of the mucosal immune system. FUNDAMENTAL AND CLINICAL IMMUNOLOGY, 4(3-4), 87-94.
M cell: the main entrance of the mucosal immune system
REGOLI, M.;BERTELLI, E.;NICOLETTI, C.
1996-01-01
Abstract
M cells are higly specialized cells within the follicle-associated epithelium (FAE) of the respiratory and intestinal tracts. They play a central role in the induction of the mucosal immune response by transporting antigens to the lymphoid tissue. In this way the immune system may encounter the limitless variety of antigens that enter the body through the gut and airways. Here we describe the structure and the function of intestinal M cells. In addition, controversial issues relating to the M cell biology, such as APC function and the origin of M cells within the FAE, are discussed.
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https://hdl.handle.net/11365/10931
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