A preliminary identification of endogenous and exogenous methylated purine bases in urinary extracts of healthy and tumor-bearing subjects has been performed using high performance liquid chromatography, and tandem mass spectrometry (MS/MS). MS/MS gave particularly fast and sensitive analyses, allowing the simultaneous and rapid determination of 26 different urinary methylated purines. Both sets of data confirm that tumor-bearing patients show changed levels of methylated purine bases
Porcelli, B., Pagani, R., Lorenzini, L., DE MARTINO, A., Catinella, S., Traldi, P. (1994). Different mass spectrometric approaches in the identification of endogenous methylated purine bases in urine extracts. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 8(6), 443-450 [10.1002/rcm.1290080603].
Different mass spectrometric approaches in the identification of endogenous methylated purine bases in urine extracts
PORCELLI, BRUNETTA;
1994-01-01
Abstract
A preliminary identification of endogenous and exogenous methylated purine bases in urinary extracts of healthy and tumor-bearing subjects has been performed using high performance liquid chromatography, and tandem mass spectrometry (MS/MS). MS/MS gave particularly fast and sensitive analyses, allowing the simultaneous and rapid determination of 26 different urinary methylated purines. Both sets of data confirm that tumor-bearing patients show changed levels of methylated purine bases
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https://hdl.handle.net/11365/10904
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