Neisseria meningitidis is an encapsulated Gram-negative bacterium responsible for significant morbidity and mortality worldwide. The availability of meningococcal genome sequences in combination with the rapid growth of proteomic techniques and other high-throughput methods, provided new approaches to the analysis of bacterial system biology. This review considers the meningococcal reference maps so far published as a starting point aimed to elucidate bacterial physiology and pathogenicity, paying particular attention to proteins with potential vaccine and diagnostic applications.

Bernardini, G., Braconi, D., & Santucci, A. (2007). The analysis of Neisseria meningitidis proteomes: reference maps and their applications. PROTEOMICS, 7(16), 2933-2946 [10.1002/pmic.200700094].

The analysis of Neisseria meningitidis proteomes: reference maps and their applications

BERNARDINI, GIULIA;BRACONI, DANIELA;SANTUCCI, ANNALISA
2007

Abstract

Neisseria meningitidis is an encapsulated Gram-negative bacterium responsible for significant morbidity and mortality worldwide. The availability of meningococcal genome sequences in combination with the rapid growth of proteomic techniques and other high-throughput methods, provided new approaches to the analysis of bacterial system biology. This review considers the meningococcal reference maps so far published as a starting point aimed to elucidate bacterial physiology and pathogenicity, paying particular attention to proteins with potential vaccine and diagnostic applications.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/10720
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