HIV RNA monitoring is not available in most antiretroviral treatment (ART) programs in sub-Saharan Africa; switch to second-line therapy is mostly guided by clinical/immunological criteria. This may lead to unnecessary disease progression and drug resistance accumulation. We investigated the prognostic value of virological and immunological status 6 months after ART initiation with respect to death, loss to follow-up, and treatment switch.
DE LUCA, A., Marazzi, M., Mancinelli, S., Ceffa, S., Altan, A., Buonomo, E., et al. (2012). Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa. JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 59(3), 236-244 [10.1097/QAI.0b013e31824276e9].
Prognostic value of virological and immunological responses after 6 months of antiretroviral treatment in adults with HIV-1 infection in sub-Saharan Africa
DE LUCA, ANDREA
;
2012-01-01
Abstract
HIV RNA monitoring is not available in most antiretroviral treatment (ART) programs in sub-Saharan Africa; switch to second-line therapy is mostly guided by clinical/immunological criteria. This may lead to unnecessary disease progression and drug resistance accumulation. We investigated the prognostic value of virological and immunological status 6 months after ART initiation with respect to death, loss to follow-up, and treatment switch.
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https://hdl.handle.net/11365/1011711
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