The reaction of 1,2-diaza-1,3-butadienes with dibenzyl diisopropylphosphoramidite, methyl tetraisopropylphosphorodiamidite or tris(dimethylamino)phosphane under solventfree conditions gave stable α-phosphoranylidene-hydrazones that, in turn, were transformed into the corresponding 5-oxo-4-phosphoranylidene-4,5-dihydro-1H-pyrazoles. X-ray diffraction analysis of one of these derivatives is reported. α-Phosphoranylidene-hydrazones, derived from the reaction between 1,2-diaza-1,3-butadienes with dibenzyl diisopropylphosphoramidite, were converted by hydrolytic cleavage into (E)-hydrazono-phosphonates, which are useful for the preparation of the corresponding (3-oxo-2,3-dihydro-1H-pyrazol-4- yl)phosphonamidates.

ATTANASI O., A., Baccolini, G., Boga, C., DE CRESCENTINI, L., Giorgi, G., Mantellini, F., et al. (2008). Reaction of 1,2-Diaza-1,3-butadienes with Aminophosphorus Nucleophiles: A Practical Access to New Phosphorylated Pyrazolones. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY(35), 5965-5973 [10.1002/ejoc.200800856].

Reaction of 1,2-Diaza-1,3-butadienes with Aminophosphorus Nucleophiles: A Practical Access to New Phosphorylated Pyrazolones

GIORGI, GIANLUCA;
2008

Abstract

The reaction of 1,2-diaza-1,3-butadienes with dibenzyl diisopropylphosphoramidite, methyl tetraisopropylphosphorodiamidite or tris(dimethylamino)phosphane under solventfree conditions gave stable α-phosphoranylidene-hydrazones that, in turn, were transformed into the corresponding 5-oxo-4-phosphoranylidene-4,5-dihydro-1H-pyrazoles. X-ray diffraction analysis of one of these derivatives is reported. α-Phosphoranylidene-hydrazones, derived from the reaction between 1,2-diaza-1,3-butadienes with dibenzyl diisopropylphosphoramidite, were converted by hydrolytic cleavage into (E)-hydrazono-phosphonates, which are useful for the preparation of the corresponding (3-oxo-2,3-dihydro-1H-pyrazol-4- yl)phosphonamidates.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11365/10097
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