Polycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5-10 % of women of reproductive age. It generally manifests with oligo/anovulatory cycles, hirsutism and polycystic ovaries, together with a considerable prevalence of insulin resistance. Although the aetiology of the syndrome is not completely understood yet, PCOS is considered a multifactorial disorder with various genetic, endocrine and environmental abnormalities. Moreover, PCOS patients have a higher risk of metabolic and cardiovascular diseases and their related morbidity, if compared to the general population. © 2016 The Author(s).
De Leo, V., Musacchio, M.C., Cappelli, V., Massaro, M.G., Morgante, G., Petraglia, F. (2016). Genetic, hormonal and metabolic aspects of PCOS: an update. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 14(1), 1-17 [10.1186/s12958-016-0173-x].
Genetic, hormonal and metabolic aspects of PCOS: an update
De Leo, V.;Cappelli, V.;Morgante, G.;
2016-01-01
Abstract
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder affecting 5-10 % of women of reproductive age. It generally manifests with oligo/anovulatory cycles, hirsutism and polycystic ovaries, together with a considerable prevalence of insulin resistance. Although the aetiology of the syndrome is not completely understood yet, PCOS is considered a multifactorial disorder with various genetic, endocrine and environmental abnormalities. Moreover, PCOS patients have a higher risk of metabolic and cardiovascular diseases and their related morbidity, if compared to the general population. © 2016 The Author(s).
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https://hdl.handle.net/11365/1005959