The role of in vivo confocal microscopy in the diagnosis of eyelid margin tumors: 47 cases

Cinotti, Elisa; Perrot, Jean Luc; Campolmi, Nelly; Labeille, Bruno; Espinasse, Marine; Grivet, Damien; Thuret, Gilles; Gain, Philippe; Douchet, Catherine; Forest, Fabien; Haouas, Maher; Cambazard, Frédéric

doi:10.1016/j.jaad.2014.05.060

CINECA IRIS Institutional Research Information System

IRIS è la soluzione IT che facilita la raccolta e la gestione dei dati relativi alle attività e ai prodotti della ricerca. Fornisce a ricercatori, amministratori e valutatori gli strumenti per monitorare i risultati della ricerca, aumentarne la visibilità e allocare in modo efficace le risorse disponibili.

BACKGROUND: Handheld in vivo reflectance confocal microscopy (IVCM) is a new imaging method that allows noninvasive diagnosis of cutaneous tumors but to date it has not been used in the study of eyelid tumors. OBJECTIVE: We sought to evaluate the suitability of IVCM for eyelid margin tumors. METHODS: We prospectively evaluated the IVCM features of 47 eyelid margin lesions, clinically suspicious of malignancy; 35 of these were excised whereas the other 12, with no IVCM malignant features, were followed up for at least 1 year. Clinical, IVCM, and histologic diagnoses were compared. RESULTS: IVCM showed sensitivity and specificity of 100% and 69.2%, respectively, for malignancy (basal cell carcinoma, squamous cell carcinoma, and melanoma). The follow-up of the 12 nonexcised lesions did not show any clinical progression. LIMITATIONS: The lesions showing neither clinical nor IVCM features for malignancies were not biopsied in view of the potential functional and aesthetic consequences of eyelid margin surgery. CONCLUSION: Used with a handheld dermatology-specific microscope, IVCM can play a role in the noninvasive diagnosis of eyelid margin lesions. Further studies are needed to better define diagnostic criteria of eyelid tumors and improve the specificity of this technique.

Scheda prodotto non validato

Scheda prodotto in fase di analisi da parte dello staff di validazione

Titolo:	The role of in vivo confocal microscopy in the diagnosis of eyelid margin tumors: 47 cases
Autori:	CINOTTI, ELISA Perrot, Jean Luc Campolmi, Nelly Labeille, Bruno Espinasse, Marine Grivet, Damien Thuret, Gilles Gain, Philippe Douchet, Catherine Forest, Fabien Haouas, Maher Cambazard, Frédéric mostra contributor esterni nascondi contributor esterni
Rivista:	JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
Citazione:	Cinotti, E., Perrot, J.L., Campolmi, N., Labeille, B., Espinasse, M., Grivet, D., et al. (2014). The role of in vivo confocal microscopy in the diagnosis of eyelid margin tumors: 47 cases. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 71(5), 912-918.
Anno:	2014
Appare nelle tipologie:	1.1 Articolo in rivista

File in questo prodotto:

Non ci sono file associati a questo prodotto.

Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11365/1003077

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.