POGGIALINI, FEDERICA
POGGIALINI, FEDERICA
Dipartimento di Biotecnologie, Chimica e Farmacia
(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity
2020-01-01 Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y.
A Greener Technique for Microwave-Assisted O-Silylation and Silyl Ether Deprotection of Uridine and Other Substrates
2022-01-01 Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E.
Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA
2022-01-01 D'Agostino, I.; Ardino, C.; Poli, G.; Sannio, F.; Lucidi, M.; Poggialini, F.; Visaggio, D.; Rango, E.; Filippi, S.; Petricci, E.; Visca, P.; Botta, L.; Docquier, J. -D.; Dreassi, E.
DEAD-Box Helicase DDX3X as a Host Target against Emerging Viruses: New Insights for Medicinal Chemical Approaches
2022-01-01 Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E.
Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma
2023-01-01 Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena
Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors
2023-01-01 Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
2018-01-01 Molinari, Alessio; Fallacara, Anna Lucia; DI MARIA, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio
In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains
2020-01-01 Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M.
Investigation of in vitro and in vivo pharmacokinetics and biological evaluation of pharmacologically active compounds
2022-01-01 Poggialini, Federica
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment
2022-01-01 Di Maria, S.; Picarazzi, F.; Mori, M.; Cianciusi, A.; Carbone, A.; Crespan, E.; Perini, C.; Sabetta, S.; Deplano, S.; Poggialini, F.; Molinari, A.; Aronne, R.; Maccioni, E.; Maga, G.; Angelucci, A.; Schenone, S.; Musumeci, F.; Dreassi, E.
Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity
2022-01-01 Cesarini, Silvia; Vicenti, Ilaria; Poggialini, Federica; Secchi, Massimiliano; Giammarino, Federica; Varasi, Ilenia; Lodola, Camilla; Zazzi, Maurizio; Dreassi, Elena; Maga, Giovanni; Botta, Lorenzo; Saladino, Raffaele
Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth
2023-01-01 Maresca, Luisa; Crivaro, Enrica; Migliorini, Francesca; Anichini, Giulia; Giammona, Alessandro; Pepe, Sara; Poggialini, Federica; Vagaggini, Chiara; Giannini, Giuseppe; Sestini, Serena; Borgognoni, Lorenzo; Lapucci, Andrea; Dreassi, Elena; Taddei, Maurizio; Manetti, Fabrizio; Petricci, Elena; Stecca, Barbara
Tenebrio molitor as a Simple and Cheap Preclinical Pharmacokinetic and Toxicity Model
2023-01-01 Brai, Annalaura; Poggialini, Federica; Vagaggini, Chiara; Pasqualini, Claudia; Simoni, Sauro; Francardi, Valeria; Dreassi, Elena
The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma
2022-01-01 Rango, E.; Pastorino, F.; Brignole, C.; Mancini, A.; Poggialini, F.; Di Maria, S.; Zamperini, C.; Iovenitti, G.; Fallacara, A. L.; Sabetta, S.; Clementi, L.; Valoti, M.; Schenone, S.; Angelucci, A.; Ponzoni, M.; Dreassi, E.; Botta, M.
Tyrosine Kinase Inhibitor Si409 Has In Vitro and In Vivo Anti-Tumor Activity Against Diffuse Large B-Cell Lymphoma
2023-01-01 Rango, E.; Di Maria, S.; Zamperini, C.; Poggialini, F.; Crespan, E.; Perini, C.; Sabetta, S.; Saponara, S.; Fusi, F.; Maga, G.; Angelucci, A.; Gaudio, E.; Berton, F.; Schenone, S.; Botta, L.; Dreassi, E.; Botta, M.
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| (Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity | 1-gen-2020 | Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y. | - | |
| A Greener Technique for Microwave-Assisted O-Silylation and Silyl Ether Deprotection of Uridine and Other Substrates | 1-gen-2022 | Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E. | - | |
| Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA | 1-gen-2022 | D'Agostino, I.; Ardino, C.; Poli, G.; Sannio, F.; Lucidi, M.; Poggialini, F.; Visaggio, D.; Rango, E.; Filippi, S.; Petricci, E.; Visca, P.; Botta, L.; Docquier, J. -D.; Dreassi, E. | - | |
| DEAD-Box Helicase DDX3X as a Host Target against Emerging Viruses: New Insights for Medicinal Chemical Approaches | 1-gen-2022 | Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E. | - | |
| Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma | 1-gen-2023 | Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena | - | |
| Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors | 1-gen-2023 | Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena | - | |
| Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment | 1-gen-2018 | Molinari, Alessio; Fallacara, Anna Lucia; DI MARIA, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio | - | |
| In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains | 1-gen-2020 | Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M. | - | |
| Investigation of in vitro and in vivo pharmacokinetics and biological evaluation of pharmacologically active compounds | 1-gen-2022 | Poggialini, Federica | - | |
| Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment | 1-gen-2022 | Di Maria, S.; Picarazzi, F.; Mori, M.; Cianciusi, A.; Carbone, A.; Crespan, E.; Perini, C.; Sabetta, S.; Deplano, S.; Poggialini, F.; Molinari, A.; Aronne, R.; Maccioni, E.; Maga, G.; Angelucci, A.; Schenone, S.; Musumeci, F.; Dreassi, E. | - | |
| Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity | 1-gen-2022 | Cesarini, Silvia; Vicenti, Ilaria; Poggialini, Federica; Secchi, Massimiliano; Giammarino, Federica; Varasi, Ilenia; Lodola, Camilla; Zazzi, Maurizio; Dreassi, Elena; Maga, Giovanni; Botta, Lorenzo; Saladino, Raffaele | - | |
| Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth | 1-gen-2023 | Maresca, Luisa; Crivaro, Enrica; Migliorini, Francesca; Anichini, Giulia; Giammona, Alessandro; Pepe, Sara; Poggialini, Federica; Vagaggini, Chiara; Giannini, Giuseppe; Sestini, Serena; Borgognoni, Lorenzo; Lapucci, Andrea; Dreassi, Elena; Taddei, Maurizio; Manetti, Fabrizio; Petricci, Elena; Stecca, Barbara | - | |
| Tenebrio molitor as a Simple and Cheap Preclinical Pharmacokinetic and Toxicity Model | 1-gen-2023 | Brai, Annalaura; Poggialini, Federica; Vagaggini, Chiara; Pasqualini, Claudia; Simoni, Sauro; Francardi, Valeria; Dreassi, Elena | - | |
| The Pyrazolo[3,4-d]Pyrimidine Derivative Si306 Encapsulated into Anti-GD2-Immunoliposomes as Therapeutic Treatment of Neuroblastoma | 1-gen-2022 | Rango, E.; Pastorino, F.; Brignole, C.; Mancini, A.; Poggialini, F.; Di Maria, S.; Zamperini, C.; Iovenitti, G.; Fallacara, A. L.; Sabetta, S.; Clementi, L.; Valoti, M.; Schenone, S.; Angelucci, A.; Ponzoni, M.; Dreassi, E.; Botta, M. | - | |
| Tyrosine Kinase Inhibitor Si409 Has In Vitro and In Vivo Anti-Tumor Activity Against Diffuse Large B-Cell Lymphoma | 1-gen-2023 | Rango, E.; Di Maria, S.; Zamperini, C.; Poggialini, F.; Crespan, E.; Perini, C.; Sabetta, S.; Saponara, S.; Fusi, F.; Maga, G.; Angelucci, A.; Gaudio, E.; Berton, F.; Schenone, S.; Botta, L.; Dreassi, E.; Botta, M. | - |