POGGIALINI, FEDERICA
POGGIALINI, FEDERICA
Dipartimento di Biotecnologie, Chimica e Farmacia
(Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity
2020-01-01 Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y.
A Facile Access to Green Fluorescent Albumin Derivatives
2024-01-01 Saletti, M.; Paolino, M.; Venditti, J.; Bonechi, C.; Giuliani, G.; Lamponi, S.; Tassone, G.; Boccia, A.; Botta, C.; Blancafort, L.; Poggialini, F.; Vagaggini, C.; Cappelli, A.
A greener technique for microwave-assisted O-Silylation and silyl ether deprotection of uridine and other substrates
2022-01-01 Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E.
A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides
2024-01-01 Ermini, Elena; Brai, Annalaura; Cini, Elena; Finetti, Federica; Giannini, Giuseppe; Padula, Daniele; Paradisi, Lucrezia; Poggialini, Federica; Trabalzini, Lorenza; Tolu, Paola; Taddei, Maurizio
Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA
2022-01-01 D'Agostino, I.; Ardino, C.; Poli, G.; Sannio, F.; Lucidi, M.; Poggialini, F.; Visaggio, D.; Rango, E.; Filippi, S.; Petricci, E.; Visca, P.; Botta, L.; Docquier, J. -D.; Dreassi, E.
Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma
2024-01-01 Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
2023-01-01 Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Musumeci, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena
DEAD-Box Helicase DDX3X as a host target against emerging viruses: new insights for medicinal chemical approaches
2022-01-01 Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E.
Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma
2023-01-01 Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena
Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors
2023-01-01 Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena
Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment
2024-01-01 Vagaggini, Chiara; Petroni, Debora; D'Agostino, Ilaria; Poggialini, Federica; Cavallini, Chiara; Cianciusi, Annarita; Salis, Annalisa; D'Antona, Lucia; Francesconi, Valeria; Manetti, Fabrizio; Damonte, Gianluca; Musumeci, Francesca; Menichetti, Luca; Dreassi, Elena; Carbone, Anna; Schenone, Silvia
Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment
2018-01-01 Molinari, Alessio; Fallacara, Anna Lucia; DI MARIA, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio
Efficient use of agricultural waste to naturally fortify Tenebrio molitor mealworms and evaluation of their nutraceutical properties
2023-01-01 Brai, A.; Poggialini, F.; Trivisani, C. I.; Vagaggini, C.; Tarchi, F.; Francardi, V.; Dreassi, E.
Exploiting fall foliage by-products to optimize Tenebrio molitor nutraceutical value
2023-01-01 Brai, A.; Provenzani, M. P.; Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Tarchi, F.; Frosinini, R.; Francardi, V.; Simoni, S.; Dreassi, E.
In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains
2020-01-01 Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M.
Investigation of in vitro and in vivo pharmacokinetics and biological evaluation of pharmacologically active compounds
2022-01-01 Poggialini, Federica
Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents
2024-01-01 Maramai, S.; Saletti, M.; Paolino, M.; Giuliani, G.; Cazzola, J.; Spaiardi, P.; Talpo, F.; Frosini, M.; Pifferi, A.; Ballarotto, M.; Carotti, A.; Poggialini, F.; Vagaggini, C.; Dreassi, E.; Giorgi, G.; Dondio, G.; Cappelli, A.; Rosario Biella, G.; Anzini, M.
Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: synthesis and biological evaluation for chronic myeloid leukemia treatment
2022-01-01 Di Maria, S.; Picarazzi, F.; Mori, M.; Cianciusi, A.; Carbone, A.; Crespan, E.; Perini, C.; Sabetta, S.; Deplano, S.; Poggialini, F.; Molinari, A.; Aronne, R.; Maccioni, E.; Maga, G.; Angelucci, A.; Schenone, S.; Musumeci, F.; Dreassi, E.
Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization
2024-01-01 Bonomini, Anna; Felicetti, Tommaso; Pacetti, Martina; Bertagnin, Chiara; Coletti, Alice; Giammarino, Federica; De Angelis, Marta; Poggialini, Federica; Macchiarulo, Antonio; Sabatini, Stefano; Mercorelli, Beatrice; Nencioni, Lucia; Vicenti, Ilaria; Dreassi, Elena; Cecchetti, Violetta; Tabarrini, Oriana; Loregian, Arianna; Massari, Serena
Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity
2022-01-01 Cesarini, Silvia; Vicenti, Ilaria; Poggialini, Federica; Secchi, Massimiliano; Giammarino, Federica; Varasi, Ilenia; Lodola, Camilla; Zazzi, Maurizio; Dreassi, Elena; Maga, Giovanni; Botta, Lorenzo; Saladino, Raffaele
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| (Thia)calixarenephosphonic Acids as Potent Inhibitors of the Nucleic Acid Chaperone Activity of the HIV-1 Nucleocapsid Protein with a New Binding Mode and Multitarget Antiviral Activity | 1-gen-2020 | Humbert, N; Kovalenko, L; Saladini, F; Giannini, A; Pires, M; Botzanowski, T; Cherenok, S; Boudier, C; Sharma, Kk; Real, E; Zaporozhets, Oa; Cianférani, S; Seguin-Devaux, C; Poggialini, F; Botta, M; Zazzi, M; Kalchenko, Vi; Mori, M; Mély, Y. | - | |
| A Facile Access to Green Fluorescent Albumin Derivatives | 1-gen-2024 | Saletti, M.; Paolino, M.; Venditti, J.; Bonechi, C.; Giuliani, G.; Lamponi, S.; Tassone, G.; Boccia, A.; Botta, C.; Blancafort, L.; Poggialini, F.; Vagaggini, C.; Cappelli, A. | - | |
| A greener technique for microwave-assisted O-Silylation and silyl ether deprotection of uridine and other substrates | 1-gen-2022 | Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E. | - | |
| A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides | 1-gen-2024 | Ermini, Elena; Brai, Annalaura; Cini, Elena; Finetti, Federica; Giannini, Giuseppe; Padula, Daniele; Paradisi, Lucrezia; Poggialini, Federica; Trabalzini, Lorenza; Tolu, Paola; Taddei, Maurizio | - | |
| Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA | 1-gen-2022 | D'Agostino, I.; Ardino, C.; Poli, G.; Sannio, F.; Lucidi, M.; Poggialini, F.; Visaggio, D.; Rango, E.; Filippi, S.; Petricci, E.; Visca, P.; Botta, L.; Docquier, J. -D.; Dreassi, E. | - | |
| Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma | 1-gen-2024 | Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia | - | |
| Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme | 1-gen-2023 | Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Musumeci, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena | - | |
| DEAD-Box Helicase DDX3X as a host target against emerging viruses: new insights for medicinal chemical approaches | 1-gen-2022 | Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E. | - | |
| Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma | 1-gen-2023 | Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena | - | |
| Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors | 1-gen-2023 | Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena | - | |
| Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment | 1-gen-2024 | Vagaggini, Chiara; Petroni, Debora; D'Agostino, Ilaria; Poggialini, Federica; Cavallini, Chiara; Cianciusi, Annarita; Salis, Annalisa; D'Antona, Lucia; Francesconi, Valeria; Manetti, Fabrizio; Damonte, Gianluca; Musumeci, Francesca; Menichetti, Luca; Dreassi, Elena; Carbone, Anna; Schenone, Silvia | - | |
| Efficient optimization of pyrazolo[3,4-d]pyrimidines derivatives as c-Src kinase inhibitors in neuroblastoma treatment | 1-gen-2018 | Molinari, Alessio; Fallacara, Anna Lucia; DI MARIA, Salvatore; Zamperini, Claudio; Poggialini, Federica; Musumeci, Francesca; Schenone, Silvia; Angelucci, Adriano; Colapietro, Alessandro; Crespan, Emmanuele; Kissova, Miroslava; Maga, Giovanni; Botta, Maurizio | - | |
| Efficient use of agricultural waste to naturally fortify Tenebrio molitor mealworms and evaluation of their nutraceutical properties | 1-gen-2023 | Brai, A.; Poggialini, F.; Trivisani, C. I.; Vagaggini, C.; Tarchi, F.; Francardi, V.; Dreassi, E. | - | |
| Exploiting fall foliage by-products to optimize Tenebrio molitor nutraceutical value | 1-gen-2023 | Brai, A.; Provenzani, M. P.; Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Tarchi, F.; Frosinini, R.; Francardi, V.; Simoni, S.; Dreassi, E. | - | |
| In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains | 1-gen-2020 | Orofino, F.; Truglio, G. I.; Fiorucci, D.; D'Agostino, I.; Borgini, M.; Poggialini, F.; Zamperini, C.; Dreassi, E.; Maccari, L.; Torelli, R.; Martini, C.; Bernabei, M.; Meis, J. F.; Khandelwal, N. K.; Prasad, R.; Sanguinetti, M.; Bugli, F.; Botta, M. | - | |
| Investigation of in vitro and in vivo pharmacokinetics and biological evaluation of pharmacologically active compounds | 1-gen-2022 | Poggialini, Federica | - | |
| Novel multitarget directed ligands inspired by riluzole: A serendipitous synthesis of substituted benzo[b][1,4]thiazepines potentially useful as neuroprotective agents | 1-gen-2024 | Maramai, S.; Saletti, M.; Paolino, M.; Giuliani, G.; Cazzola, J.; Spaiardi, P.; Talpo, F.; Frosini, M.; Pifferi, A.; Ballarotto, M.; Carotti, A.; Poggialini, F.; Vagaggini, C.; Dreassi, E.; Giorgi, G.; Dondio, G.; Cappelli, A.; Rosario Biella, G.; Anzini, M. | - | |
| Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: synthesis and biological evaluation for chronic myeloid leukemia treatment | 1-gen-2022 | Di Maria, S.; Picarazzi, F.; Mori, M.; Cianciusi, A.; Carbone, A.; Crespan, E.; Perini, C.; Sabetta, S.; Deplano, S.; Poggialini, F.; Molinari, A.; Aronne, R.; Maccioni, E.; Maga, G.; Angelucci, A.; Schenone, S.; Musumeci, F.; Dreassi, E. | - | |
| Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization | 1-gen-2024 | Bonomini, Anna; Felicetti, Tommaso; Pacetti, Martina; Bertagnin, Chiara; Coletti, Alice; Giammarino, Federica; De Angelis, Marta; Poggialini, Federica; Macchiarulo, Antonio; Sabatini, Stefano; Mercorelli, Beatrice; Nencioni, Lucia; Vicenti, Ilaria; Dreassi, Elena; Cecchetti, Violetta; Tabarrini, Oriana; Loregian, Arianna; Massari, Serena | - | |
| Privileged Scaffold Decoration for the Identification of the First Trisubstituted Triazine with Anti-SARS-CoV-2 Activity | 1-gen-2022 | Cesarini, Silvia; Vicenti, Ilaria; Poggialini, Federica; Secchi, Massimiliano; Giammarino, Federica; Varasi, Ilenia; Lodola, Camilla; Zazzi, Maurizio; Dreassi, Elena; Maga, Giovanni; Botta, Lorenzo; Saladino, Raffaele | - |