VAGAGGINI, CHIARA
VAGAGGINI, CHIARA
Dipartimento di Biotecnologie, Chimica e Farmacia
A Facile Access to Green Fluorescent Albumin Derivatives
2024-01-01 Saletti, M.; Paolino, M.; Venditti, J.; Bonechi, C.; Giuliani, G.; Lamponi, S.; Tassone, G.; Boccia, A.; Botta, C.; Blancafort, L.; Poggialini, F.; Vagaggini, C.; Cappelli, A.
A greener technique for microwave-assisted O-Silylation and silyl ether deprotection of uridine and other substrates
2022-01-01 Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E.
Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma
2024-01-01 Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia
Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme
2023-01-01 Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Musumeci, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena
Characterization of in vitro and in vivo properties of pharmacologically active compounds in a GLP-Like laboratory
2024-06-14 Vagaggini, Chiara
DEAD-Box Helicase DDX3X as a host target against emerging viruses: new insights for medicinal chemical approaches
2022-01-01 Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E.
Deciphering the landscape of allosteric glutaminase 1 inhibitors as anticancer agents
2025-01-01 Vagaggini, C.; D'Ursi, P.; Poggialini, F.; Fossa, P.; Francesconi, V.; Trombetti, G.; Orro, A.; Dreassi, E.; Schenone, S.; Tonelli, M.; Carbone, A.
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors
2024-01-01 Di Stefano, M.; Masoni, S.; Bononi, G.; Poli, G.; Galati, S.; Gado, F.; Manzi, S.; Vagaggini, C.; Brai, A.; Caligiuri, I.; Asif, K.; Rizzolio, F.; Macchia, M.; Chicca, A.; Sodi, A.; Di Bussolo, V.; Minutolo, F.; Meier, P.; Gertsch, J.; Granchi, C.; Dreassi, E.; Tuccinardi, T.
Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma
2023-01-01 Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena
Discovery of reversible monoacylglycerol lipase (MAGL) inhibitors based on ortho-hydroxyanilide scaffold
2025-01-01 Bononi, G.; Gado, F.; Masoni, S.; Scalabrini, D.; Vedova, L. D.; Di Stefano, M.; Piazza, L.; Poles, C.; Lonzi, C.; Landucci, E.; Vagaggini, C.; Poggialini, F.; Brai, A.; Caligiuri, I.; Rizzolio, F.; Mohamed, K. A.; Bertini, S.; De Lorenzi, E.; Dreassi, E.; Macchia, M.; Minutolo, F.; Laprairie, R. B.; Granchi, C.; Tuccinardi, T.
Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment
2024-01-01 Vagaggini, Chiara; Petroni, Debora; D'Agostino, Ilaria; Poggialini, Federica; Cavallini, Chiara; Cianciusi, Annarita; Salis, Annalisa; D'Antona, Lucia; Francesconi, Valeria; Manetti, Fabrizio; Damonte, Gianluca; Musumeci, Francesca; Menichetti, Luca; Dreassi, Elena; Carbone, Anna; Schenone, Silvia
Efficient use of agricultural waste to naturally fortify Tenebrio molitor mealworms and evaluation of their nutraceutical properties
2023-01-01 Brai, A.; Poggialini, F.; Trivisani, C. I.; Vagaggini, C.; Tarchi, F.; Francardi, V.; Dreassi, E.
Evaluation of anti-tumoral activity in 3D cell model of a Src inhibitor prodrug for glioblastoma treatment
2025-01-01 Clementi, L.; Poggialini, F.; Musumeci, F.; Taglienti, J.; Cornacchia, E.; Vagaggini, C.; Carbone, A.; Grossi, G.; Dreassi, E.; Angelucci, A.; Schenone, S.
Exploitation of the Nutraceutical Potential of the Infesting Seaweed Chaetomorpha linum as a Yellow Mealworms’ Feed: Focus on Nutrients and Antioxidant Activity
2025-01-01 Brai, A.; Brogi, E.; Tarchi, F.; Poggialini, F.; Vagaggini, C.; Simoni, S.; Francardi, V.; Dreassi, E
Exploiting fall foliage by-products to optimize Tenebrio molitor nutraceutical value
2024-01-01 Brai, A.; Provenzani, M. P.; Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Tarchi, F.; Frosinini, R.; Francardi, V.; Simoni, S.; Dreassi, E.
Fluoromethylcarnitine, a novel inhibitor of trimethylamine levels in trimethylaminuria and trimethylamine N-oxide related disorders
2025-01-01 Cini, Elena; Vinciarelli, Giorgia; Siciliano, Sofia; Del Castello, Giorgio; Dreassi, Elena; Poggialini, Federica; Vagaggini, Chiara; Taddei, Maurizio; Battistuzzi, Gianfranco; Castagnetti, Andrea; Viciani, Elisa; Salvini, Laura; Sidoti, Antonina; Alibrandi, Simona; Giannini, Giuseppe
Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents
2022-01-01 Balestri, Lorenzo J. I.; D’Agostino, Ilaria; Rango, Enrico; Vagaggini, Chiara; Marchitiello, Rosalba; Mariotti, Melinda; Casian, Alexandru; Deodato, Davide; Truglio, Giuseppina I.; Orofino, Francesco; Sanguinetti, Maurizio; Bugli, Francesca; Botta, Lorenzo; Dreassi, Elena
Harnessing prebiotic formamide chemistry: a novel platform for antiviral exploration
2025-01-01 Martina, M. G.; Vagaggini, C.; Dreassi, E.; De Angelis, M.; Nencioni, L.; Dragoni, F.; Giammarino, F.; Boccuto, A.; Zazzi, M.; Vicenti, I.; Radi, M.
Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity
2024-01-01 Fiorucci, D.; Meaccini, M.; Poli, G.; Stincarelli, M. A.; Vagaggini, C.; Giannecchini, S.; Sutto-Ortiz, P.; Canard, B.; Decroly, E.; Dreassi, E.; Brai, A.; Botta, M.
Infesting Seaweeds as a Novel Functional Food: Analysis of Nutrients, Antioxidants and ACE Inhibitory Effects
2024-01-01 Brai, Annalaura; Hasanaj, Anjeza; Vagaggini, Chiara; Poggialini, Federica; Dreassi, Elena
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A Facile Access to Green Fluorescent Albumin Derivatives | 1-gen-2024 | Saletti, M.; Paolino, M.; Venditti, J.; Bonechi, C.; Giuliani, G.; Lamponi, S.; Tassone, G.; Boccia, A.; Botta, C.; Blancafort, L.; Poggialini, F.; Vagaggini, C.; Cappelli, A. | - | |
| A greener technique for microwave-assisted O-Silylation and silyl ether deprotection of uridine and other substrates | 1-gen-2022 | Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Brai, A.; Dreassi, E. | - | |
| Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma | 1-gen-2024 | Di Maria, Salvatore; Passannanti, Raffaele; Poggialini, Federica; Vagaggini, Chiara; Serafinelli, Alessia; Bianchi, Elena; Governa, Paolo; Botta, Lorenzo; Maga, Giovanni; Crespan, Emmanuele; Manetti, Fabrizio; Dreassi, Elena; Musumeci, Francesca; Carbone, Anna; Schenone, Silvia | - | |
| Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-d]pyrimidines as Dual Tyrosine Kinase Inhibitors Active against Glioblastoma Multiforme | 1-gen-2023 | Poggialini, Federica; Vagaggini, Chiara; Brai, Annalaura; Pasqualini, Claudia; Crespan, Emmanuele; Maga, Giovanni; Perini, Cecilia; Cabella, Noemi; Botta, Lorenzo; Musumeci, Francesca; Frosini, Maria; Schenone, Silvia; Dreassi, Elena | - | |
| Characterization of in vitro and in vivo properties of pharmacologically active compounds in a GLP-Like laboratory | 14-giu-2024 | Vagaggini, Chiara | - | |
| DEAD-Box Helicase DDX3X as a host target against emerging viruses: new insights for medicinal chemical approaches | 1-gen-2022 | Brai, A.; Trivisani, C. I.; Poggialini, F.; Pasqualini, C.; Vagaggini, C.; Dreassi, E. | - | |
| Deciphering the landscape of allosteric glutaminase 1 inhibitors as anticancer agents | 1-gen-2025 | Vagaggini, C.; D'Ursi, P.; Poggialini, F.; Fossa, P.; Francesconi, V.; Trombetti, G.; Orro, A.; Dreassi, E.; Schenone, S.; Tonelli, M.; Carbone, A. | - | |
| Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors | 1-gen-2024 | Di Stefano, M.; Masoni, S.; Bononi, G.; Poli, G.; Galati, S.; Gado, F.; Manzi, S.; Vagaggini, C.; Brai, A.; Caligiuri, I.; Asif, K.; Rizzolio, F.; Macchia, M.; Chicca, A.; Sodi, A.; Di Bussolo, V.; Minutolo, F.; Meier, P.; Gertsch, J.; Granchi, C.; Dreassi, E.; Tuccinardi, T. | - | |
| Development and validation of derivatization-based LC-MS/MS method for quantification of short-chain fatty acids in human, rat, and mouse plasma | 1-gen-2023 | Vagaggini, Chiara; Brai, Annalaura; Bonente, Denise; Lombardi, Jessica; Poggialini, Federica; Pasqualini, Claudia; Barone, Virginia; Nicoletti, Claudio; Bertelli, Eugenio; Dreassi, Elena | - | |
| Discovery of reversible monoacylglycerol lipase (MAGL) inhibitors based on ortho-hydroxyanilide scaffold | 1-gen-2025 | Bononi, G.; Gado, F.; Masoni, S.; Scalabrini, D.; Vedova, L. D.; Di Stefano, M.; Piazza, L.; Poles, C.; Lonzi, C.; Landucci, E.; Vagaggini, C.; Poggialini, F.; Brai, A.; Caligiuri, I.; Rizzolio, F.; Mohamed, K. A.; Bertini, S.; De Lorenzi, E.; Dreassi, E.; Macchia, M.; Minutolo, F.; Laprairie, R. B.; Granchi, C.; Tuccinardi, T. | - | |
| Early investigation of a novel SI306 theranostic prodrug for glioblastoma treatment | 1-gen-2024 | Vagaggini, Chiara; Petroni, Debora; D'Agostino, Ilaria; Poggialini, Federica; Cavallini, Chiara; Cianciusi, Annarita; Salis, Annalisa; D'Antona, Lucia; Francesconi, Valeria; Manetti, Fabrizio; Damonte, Gianluca; Musumeci, Francesca; Menichetti, Luca; Dreassi, Elena; Carbone, Anna; Schenone, Silvia | - | |
| Efficient use of agricultural waste to naturally fortify Tenebrio molitor mealworms and evaluation of their nutraceutical properties | 1-gen-2023 | Brai, A.; Poggialini, F.; Trivisani, C. I.; Vagaggini, C.; Tarchi, F.; Francardi, V.; Dreassi, E. | - | |
| Evaluation of anti-tumoral activity in 3D cell model of a Src inhibitor prodrug for glioblastoma treatment | 1-gen-2025 | Clementi, L.; Poggialini, F.; Musumeci, F.; Taglienti, J.; Cornacchia, E.; Vagaggini, C.; Carbone, A.; Grossi, G.; Dreassi, E.; Angelucci, A.; Schenone, S. | - | |
| Exploitation of the Nutraceutical Potential of the Infesting Seaweed Chaetomorpha linum as a Yellow Mealworms’ Feed: Focus on Nutrients and Antioxidant Activity | 1-gen-2025 | Brai, A.; Brogi, E.; Tarchi, F.; Poggialini, F.; Vagaggini, C.; Simoni, S.; Francardi, V.; Dreassi, E | - | |
| Exploiting fall foliage by-products to optimize Tenebrio molitor nutraceutical value | 1-gen-2024 | Brai, A.; Provenzani, M. P.; Pasqualini, C.; Poggialini, F.; Vagaggini, C.; Tarchi, F.; Frosinini, R.; Francardi, V.; Simoni, S.; Dreassi, E. | - | |
| Fluoromethylcarnitine, a novel inhibitor of trimethylamine levels in trimethylaminuria and trimethylamine N-oxide related disorders | 1-gen-2025 | Cini, Elena; Vinciarelli, Giorgia; Siciliano, Sofia; Del Castello, Giorgio; Dreassi, Elena; Poggialini, Federica; Vagaggini, Chiara; Taddei, Maurizio; Battistuzzi, Gianfranco; Castagnetti, Andrea; Viciani, Elisa; Salvini, Laura; Sidoti, Antonina; Alibrandi, Simona; Giannini, Giuseppe | - | |
| Focused library of phenyl-fused macrocyclic amidinoureas as antifungal agents | 1-gen-2022 | Balestri, Lorenzo J. I.; D’Agostino, Ilaria; Rango, Enrico; Vagaggini, Chiara; Marchitiello, Rosalba; Mariotti, Melinda; Casian, Alexandru; Deodato, Davide; Truglio, Giuseppina I.; Orofino, Francesco; Sanguinetti, Maurizio; Bugli, Francesca; Botta, Lorenzo; Dreassi, Elena | - | |
| Harnessing prebiotic formamide chemistry: a novel platform for antiviral exploration | 1-gen-2025 | Martina, M. G.; Vagaggini, C.; Dreassi, E.; De Angelis, M.; Nencioni, L.; Dragoni, F.; Giammarino, F.; Boccuto, A.; Zazzi, M.; Vicenti, I.; Radi, M. | - | |
| Identification of Novel Non-Nucleoside Inhibitors of Zika Virus NS5 Protein Targeting MTase Activity | 1-gen-2024 | Fiorucci, D.; Meaccini, M.; Poli, G.; Stincarelli, M. A.; Vagaggini, C.; Giannecchini, S.; Sutto-Ortiz, P.; Canard, B.; Decroly, E.; Dreassi, E.; Brai, A.; Botta, M. | - | |
| Infesting Seaweeds as a Novel Functional Food: Analysis of Nutrients, Antioxidants and ACE Inhibitory Effects | 1-gen-2024 | Brai, Annalaura; Hasanaj, Anjeza; Vagaggini, Chiara; Poggialini, Federica; Dreassi, Elena | - |