COSTI, MARIA PAOLA

COSTI, MARIA PAOLA  

Dipartimento di Biotecnologie, Chimica e Farmacia  

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Titolo Data di pubblicazione Autore(i) File Abstract
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 1-gen-2019 Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz -
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease 1-gen-2018 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Costi, MARIA PAOLA; Mangani, Stefano -
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease 1-gen-2018 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano -
Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-beta-lactamases 1-gen-2017 Santucci, Matteo; Spyrakis, Francesca; Cross, Simon; Quotadamo, Antonio; Farina, Davide; Tondi, Donatella; De Luca, Filomena; Docquier, Jean-Denis; Prieto, Ana Isabel; Ibacache, Claudia; Blázquez, Jesús; Venturelli, Alberto; Cruciani, Gabriele; Costi, Maria Paola -
CRYSTAL STRUCTURE OF A COMPLEX OF THYMIDYLATE SYNTHASE (TS) WITH A LIGAND 1-gen-2011 Pozzi, Cecilia; Mangani, Stefano; Costi, MARIA PAOLA; Ferrari, Stefania; Guaitoli, Giambattista -
Development of flavonol and flavanone derivatives as anti-trypanosomatidic drugs 1-gen-2017 Pozzi, Cecilia; DI PISA, Flavio; Landi, Giacomo; DELLO IACONO, Lucia; Costi, MARIA PAOLA; Wade, Rebecca C.; Gul, Sheraz; Cordeiro-da-Silva, Anabela; Mangani, Stefano -
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections 1-gen-2019 Linciano, Pasquale; Pozzi, Cecilia; Iacono, Lucia Dello; di Pisa, Flavio; Landi, Giacomo; Bonucci, Alessio; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Santarem, Nuno; Baptista, Catarina; Franco, Caio; Moraes, Carolina B; Müller, Wolfgang; Wittig, Ulrike; Luciani, Rosaria; Sesenna, Antony; Quotadamo, Antonio; Ferrari, Stefania; Pöhner, Ina; Cordeiro-da-Silva, Anabela; Mangani, Stefano; Costantino, Luca; Costi, Maria Paola -
Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R 1-gen-2019 Pozzi, Cecilia; Lopresti, Ludovica; Santucci, Matteo; Costi, Maria Paola; Mangani, Stefano -
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase 1-gen-2021 Tassone, Giusy; Landi, Giacomo; Linciano, Pasquale; Francesconi, Valeria; Tonelli, Michele; Tagliazucchi, Lorenzo; Costi, Maria Paola; Mangani, Stefano; Pozzi, Cecilia -
In silico identification and in vitro evaluation of natural inhibitors of leishmania major pteridine reductase I 1-gen-2017 Herrmann, Fabian C.; Sivakumar, Nirina; Jose, Joachim; Costi, Maria P.; Pozzi, Cecilia; Schmidt, Thomas J. -
Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitors 1-gen-2019 Pozzi, Cecilia; Ferrari, Stefania; Luciani, Rosaria; Costi, Maria Paola; Mangani, Stefano -
Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilities 1-gen-2019 Pozzi, Cecilia; Ferrari, Stefania; Luciani, Rosaria; Tassone, Giusy; Costi, Maria Paola; Mangani, Stefano -
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors 1-gen-2019 Landi, Giacomo; Linciano, Pasquale; Borsari, Chiara; Bertolacini, Claudia P; Moraes, Carolina B; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Costi, Maria Paola; Pozzi, Cecilia; Mangani, Stefano -
Targeting class A and C serine β-lactamases with a broad-spectrum boronic acid derivative 1-gen-2014 Tondi, Donatella; Venturelli, Alberto; Bonnet, Richard; Pozzi, Cecilia; Shoichet, Brian K.; Costi, MARIA PAOLA -