TASSONE, GIUSY
TASSONE, GIUSY
Dipartimento di Biotecnologie, Chimica e Farmacia
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors
2022-01-01 Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity
2021-01-01 Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease
2018-01-01 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Costi, MARIA PAOLA; Mangani, Stefano
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease
2018-01-01 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano
Catechol-O-methyltransferase (COMT)
2024-01-01 Tassone, Giusy; Carradori, Simone; Maramai, Samuele; D'Agostino, Ilaria
Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02
2019-01-01 Iralde-Lorente, Leire; Cau, Ylenia; Clementi, Letizia; Franci, Lorenzo; Tassone, Giusy; Valensin, Daniela; Mori, Mattia; Angelucci, Adriano; Chiariello, Mario; Botta, Maurizio
Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells
2023-01-01 Barbera, Stefano; Raucci, Luisa; Tassone, Giusy; Tinti, Laura; Prischi, Filippo; Santucci, Annalisa; Mongiat, Maurizio; Tosi, Gian Marco; Galvagni, Federico; Dimberg, Anna; Pozzi, Cecilia; Orlandini, Maurizio
Discovery of ANT3310, a novel broad-spectrum serine β-Lactamase inhibitor of the diazabicyclooctane class, which strongly potentiates meropenem activity against carbapenem-resistant enterobacterales and acinetobacter baumannii
2020-01-01 Davies, D. T.; Leiris, S.; Zalacain, M.; Sprynski, N.; Castandet, J.; Bousquet, J.; Lozano, C.; Llanos, A.; Alibaud, L.; Vasa, S.; Pattipati, R.; Valige, R.; Kummari, B.; Pothukanuri, S.; De Piano, C.; Morrissey, I.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Tassone, G.; Mangani, S.; Docquier, J. D.; Pallin, D.; Elliot, R.; Lemonnier, M.; Everett, M.
Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone
2020-01-01 Batista, F. A. H.; Ramos, S. L.; Tassone, G.; Leitao, A.; Montanari, C. A.; Botta, M.; Mori, M.; Borges, J. C.
Dynamic interplay between copper toxicity and mitochondrial dysfunction in Alzheimer’s disease
2021-01-01 Tassone, G.; Kola, A.; Valensin, D.; Pozzi, C.
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase
2021-01-01 Tassone, Giusy; Landi, Giacomo; Linciano, Pasquale; Francesconi, Valeria; Tonelli, Michele; Tagliazucchi, Lorenzo; Costi, Maria Paola; Mangani, Stefano; Pozzi, Cecilia
Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design
2022-01-01 Palomba, Tommaso; Tassone, Giusy; Vacca, Carmine; Bartalucci, Matteo; Valeri, Aurora; Pozzi, Cecilia; Cross, Simon; Siragusa, Lydia; Desantis, Jenny
High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor
2020-01-01 Landi, Giacomo; Linciano, Pasquale; Tassone, Giusy; Costi, Maria Paola; Mangani, Stefano; Pozzi, Cecilia
Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction
2020-01-01 Iralde-Lorente, Leire; Tassone, Giusy; Clementi, Letizia; Franci, Lorenzo; Munier, Claire C; Cau, Ylenia; Mori, Mattia; Chiariello, Mario; Angelucci, Adriano; Perry, Matthew W D; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio
Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin
2021-01-01 Ciambellotti, Silvia; Pratesi, Alessandro; Tassone, Giusy; Turano, Paola; Mangani, Stefano; Pozzi, Cecilia
Mechanistic Aspects of the Asymmetric Transfer Hydrogenation in the Manufacture of Noradrenaline
2022-01-01 Scorzelli, F.; Tassone, G.; Padula, D.; Zacche, M.
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates
2022-01-01 Legru, Alice; Verdirosa, Federica; Vo-Hoang, Yen; Tassone, Giusy; Vascon, Filippo; Thomas, Caitlyn A; Sannio, Filomena; Corsica, Giuseppina; Benvenuti, Manuela; Feller, Georges; Coulon, Rémi; Marcoccia, Francesca; Devente, Savannah Rowane; Bouajila, Ezeddine; Piveteau, Catherine; Leroux, Florence; Deprez-Poulain, Rebecca; Deprez, Benoît; Licznar-Fajardo, Patricia; Crowder, Michael W; Cendron, Laura; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François; Gavara, Laurent
Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart
2018-01-01 Tassone, Giusy; Mangani, Stefano; Botta, Maurizio; Pozzi, Cecilia
Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart
2018-01-01 Tassone, Giusy; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio
Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart
2018-01-01 Tassone, Giusy; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors | 1-gen-2022 | Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François | - | |
| 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity | 1-gen-2021 | Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent | - | |
| Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease | 1-gen-2018 | Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Costi, MARIA PAOLA; Mangani, Stefano | - | |
| Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease | 1-gen-2018 | Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano | - | |
| Catechol-O-methyltransferase (COMT) | 1-gen-2024 | Tassone, Giusy; Carradori, Simone; Maramai, Samuele; D'Agostino, Ilaria | - | |
| Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02 | 1-gen-2019 | Iralde-Lorente, Leire; Cau, Ylenia; Clementi, Letizia; Franci, Lorenzo; Tassone, Giusy; Valensin, Daniela; Mori, Mattia; Angelucci, Adriano; Chiariello, Mario; Botta, Maurizio | - | |
| Dimerization of the C-type lectin-like receptor CD93 promotes its binding to Multimerin-2 in endothelial cells | 1-gen-2023 | Barbera, Stefano; Raucci, Luisa; Tassone, Giusy; Tinti, Laura; Prischi, Filippo; Santucci, Annalisa; Mongiat, Maurizio; Tosi, Gian Marco; Galvagni, Federico; Dimberg, Anna; Pozzi, Cecilia; Orlandini, Maurizio | - | |
| Discovery of ANT3310, a novel broad-spectrum serine β-Lactamase inhibitor of the diazabicyclooctane class, which strongly potentiates meropenem activity against carbapenem-resistant enterobacterales and acinetobacter baumannii | 1-gen-2020 | Davies, D. T.; Leiris, S.; Zalacain, M.; Sprynski, N.; Castandet, J.; Bousquet, J.; Lozano, C.; Llanos, A.; Alibaud, L.; Vasa, S.; Pattipati, R.; Valige, R.; Kummari, B.; Pothukanuri, S.; De Piano, C.; Morrissey, I.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Tassone, G.; Mangani, S.; Docquier, J. D.; Pallin, D.; Elliot, R.; Lemonnier, M.; Everett, M. | - | |
| Discovery of small molecule inhibitors of Leishmania braziliensis Hsp90 chaperone | 1-gen-2020 | Batista, F. A. H.; Ramos, S. L.; Tassone, G.; Leitao, A.; Montanari, C. A.; Botta, M.; Mori, M.; Borges, J. C. | - | |
| Dynamic interplay between copper toxicity and mitochondrial dysfunction in Alzheimer’s disease | 1-gen-2021 | Tassone, G.; Kola, A.; Valensin, D.; Pozzi, C. | - | |
| Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase | 1-gen-2021 | Tassone, Giusy; Landi, Giacomo; Linciano, Pasquale; Francesconi, Valeria; Tonelli, Michele; Tagliazucchi, Lorenzo; Costi, Maria Paola; Mangani, Stefano; Pozzi, Cecilia | - | |
| Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design | 1-gen-2022 | Palomba, Tommaso; Tassone, Giusy; Vacca, Carmine; Bartalucci, Matteo; Valeri, Aurora; Pozzi, Cecilia; Cross, Simon; Siragusa, Lydia; Desantis, Jenny | - | |
| High-resolution crystal structure of Trypanosoma brucei pteridine reductase 1 in complex with an innovative tricyclic-based inhibitor | 1-gen-2020 | Landi, Giacomo; Linciano, Pasquale; Tassone, Giusy; Costi, Maria Paola; Mangani, Stefano; Pozzi, Cecilia | - | |
| Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction | 1-gen-2020 | Iralde-Lorente, Leire; Tassone, Giusy; Clementi, Letizia; Franci, Lorenzo; Munier, Claire C; Cau, Ylenia; Mori, Mattia; Chiariello, Mario; Angelucci, Adriano; Perry, Matthew W D; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio | - | |
| Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin | 1-gen-2021 | Ciambellotti, Silvia; Pratesi, Alessandro; Tassone, Giusy; Turano, Paola; Mangani, Stefano; Pozzi, Cecilia | - | |
| Mechanistic Aspects of the Asymmetric Transfer Hydrogenation in the Manufacture of Noradrenaline | 1-gen-2022 | Scorzelli, F.; Tassone, G.; Padula, D.; Zacche, M. | - | |
| Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates | 1-gen-2022 | Legru, Alice; Verdirosa, Federica; Vo-Hoang, Yen; Tassone, Giusy; Vascon, Filippo; Thomas, Caitlyn A; Sannio, Filomena; Corsica, Giuseppina; Benvenuti, Manuela; Feller, Georges; Coulon, Rémi; Marcoccia, Francesca; Devente, Savannah Rowane; Bouajila, Ezeddine; Piveteau, Catherine; Leroux, Florence; Deprez-Poulain, Rebecca; Deprez, Benoît; Licznar-Fajardo, Patricia; Crowder, Michael W; Cendron, Laura; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François; Gavara, Laurent | - | |
| Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart | 1-gen-2018 | Tassone, Giusy; Mangani, Stefano; Botta, Maurizio; Pozzi, Cecilia | - | |
| Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart | 1-gen-2018 | Tassone, Giusy; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio | - | |
| Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart | 1-gen-2018 | Tassone, Giusy; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio | - |