GORELLI, BEATRICE
GORELLI, BEATRICE
3,5-dibenzoyl-4-(3-phenoxyphenyl)-1,4-dihydro-2,6-dimethylpyridine (DP7): a new multidrug resistance inhibitor devoid of effects on Langendorff-perfused rat heart
2007-01-01 Saponara, Simona; Ferrara, A; Gorelli, B; Shah, A; Kawase, M; Motohashi, N; Molnar, J; Sgaragli, GIAN PIETRO; Fusi, Fabio
Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats
2020-01-01 Pessina, F.; Frosini, M.; Marcolongo, P.; Fusi, F.; Saponara, S.; Gamberucci, A.; Valoti, M.; Giustarini, D.; Fiorenzani, P.; Gorelli, B.; Francardi, V.; Botta, M.; Dreassi, E.
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues
2018-01-01 Vallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita; Chemi, Giulia; Alfano, Gloria; Lamponi, Stefania; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability
2022-01-01 Federico, S.; Khan, T.; Fontana, A.; Brogi, S.; Benedetti, R.; Sarno, F.; Carullo, G.; Pezzotta, A.; Saraswati, A. P.; Passaro, E.; Pozzetti, L.; Papa, A.; Relitti, N.; Gemma, S.; Butini, S.; Pistocchi, A.; Ramunno, A.; Vincenzi, F.; Varani, K.; Tatangelo, V.; Patrussi, L.; Baldari, C. T.; Saponara, S.; Gorelli, B.; Lamponi, S.; Valoti, M.; Saccoccia, F.; Giannaccari, M.; Ruberti, G.; Herp, D.; Jung, M.; Altucci, L.; Campiani, G.
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
2016-01-01 Brindisi, Margherita; Maramai, Samuele; Gemma, Sandra; Brogi, Simone; Grillo, Alessandro; Di Cesare Mannelli, Lorenzo; Gabellieri, Emanuele; Lamponi, Stefania; Saponara, Simona; Gorelli, Beatrice; Tedesco, Daniele; Bonfiglio, Tommaso; Landry, Christophe; Jung, Kwang Mook; Armirotti, Andrea; Luongo, Livio; Ligresti, Alessia; Piscitelli, Fabiana; Bertucci, Carlo; Dehouck, Marie Pierre; Campiani, Giuseppe; Maione, Sabatino; Ghelardini, Carla; Pittaluga, Anna; Piomelli, Daniele; Di Marzo, Vincenzo; Butini, Stefania
Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions
2023-01-01 Papa, Alessandro; Pasquini, Silvia; Galvani, Francesca; Cammarota, Mariarosaria; Contri, Chiara; Carullo, Gabriele; Gemma, Sandra; Ramunno, Anna; Lamponi, Stefania; Gorelli, Beatrice; Saponara, Simona; Varani, Katia; Mor, Marco; Campiani, Giuseppe; Boscia, Francesca; Vincenzi, Fabrizio; Lodola, Alessio; Butini, Stefania
Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics
2012-01-01 Frosini, Maria; Larini, Alessandra; Ricci, Lorenzo; Lucas, L; Gorelli, Beatrice; Sgaragli, GIAN PIETRO; Tanganelli, Piero; Valoti, Massimo
Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors
2021-01-01 Campiani, Giuseppe; Cavella, Caterina; Osko, Jeremy D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach, Katy M; Altucci, Lucia; Bradding, Peter; Christianson, David W; Gemma, Sandra; Prasse, Antje
MC225, a novel probe for P-glycoprotein PET Imaging at the blood-brain barrier: in vitro cardiovascular safety evaluation
2017-01-01 Fusi, Fabio; Durante, Miriam; Gorelli, Beatrice; Perrone, Maria Grazia; Colabufo, Nicola Antonio; Saponara, Simona
Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak
2018-01-01 Pessina, Federica; Gamberucci, Alessandra; Chen, Jialin; Liu, Boyin; Vangheluwe, Peter; Gorelli, Beatrice; Lorenzini, Stefania; Spiga, Ottavia; Trezza, Alfonso; Sgaragli, Giampietro; Saponara, Simona
Neuroprotezione farmacologica del danno da ischemia-riperfusione nella vescica urinaria: approcci sperimentali
2001-01-01 Pessina, F.; Esposito, L.; Sconza, R.; Gorelli, B.; Matteucci, G.; Sgaragli, G. P.
Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits CaV1.2 and Stimulates KCa1.1 Channels
2022-01-01 Carullo, Gabriele; Saponara, Simona; Ahmed, Amer; Gorelli, Beatrice; Mazzotta, Sarah; Trezza, Alfonso; Gianibbi, Beatrice; Campiani, Giuseppe; Fusi, Fabio; Aiello, Francesca
On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings
2000-01-01 Fusi, Fabio; Marazova, K.; Pessina, Federica; Gorelli, Beatrice; Valoti, Massimo; Frosini, Maria; Sgaragli, GIAN PIETRO
Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling
2012-01-01 Gemma, Sandra; Camodeca, Caterina; SANNA COCCONE, Salvatore; Bhupendra P., Joshi; Bernetti, Matteo; Moretti, Vittoria; Brogi, Simone; María Cruz, Bonache; Savini, Luisa; Donatella, Taramelli; Nicoletta, Basilico; Silvia, Parapini; Matthias, Rottmann; Reto, Brun; Lamponi, Stefania; Silvio, Caccia; Giovanna, Guiso; Robert, Summer; Rowena, Martin; Saponara, Simona; Gorelli, Beatrice; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system
2014-01-01 Saponara, Simona; Durante, Miriam; Frosini, Maria; Gorelli, Beatrice; Valoti, Massimo; Chegaev, K; Sgaragli, GIAN PIETRO; Fusi, Fabio
Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature
2022-01-01 Durante, M.; Frosini, M.; Chiaino, E.; Fusi, F.; Gamberucci, A.; Gorelli, B.; Chegaev, K.; Riganti, C.; Saponara, S.
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents
2021-01-01 Grillo, Alessandro; Fezza, Filomena; Chemi, Giulia; Colangeli, Roberto; Brogi, Simone; Fazio, Domenico; Federico, Stefano; Papa, Alessandro; Relitti, Nicola; Di Maio, Roberto; Giorgi, Gianluca; Lamponi, Stefania; Valoti, Massimo; Gorelli, Beatrice; Saponara, Simona; Benedusi, Mascia; Pecorelli, Alessandra; Minetti, Patrizia; Valacchi, Giuseppe; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra; Maccarrone, Mauro; Di Giovanni, Giuseppe
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies
2014-01-01 Brindisi, Margherita; Butini, Stefania; Franceschini, Silvia; Brogi, Simone; Trotta, Francesco; Sindu, Ros; Alfredo, Cagnotto; Mario, Salmona; Casagni, Alice; Andreassi, Marco; Saponara, Simona; Gorelli, Beatrice; Pia, Weikop; Mikkelsen, Jens D.; Jorgen Scheel Kruger, ; Karin Sandager Nielsen, ; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy
2024-01-01 Carullo, Gabriele; Orsini, Noemi; Piano, Ilaria; Pozzetti, Luca; Papa, Alessandro; Fontana, Anna; Napoli, Debora; Corsi, Francesca; Marco, Beatrice Di; Galante, Alessia; Marotta, Ludovica; Panzeca, Giovanna; O'Brien, Justine; Sanchez, Alicia Gomez; Doherty, Harry; Mahon, Niamh; Clarke, Leni; Contri, Chiara; Pasquini, Silvia; Gorelli, Beatrice; Saponara, Simona; Valoti, Massimo; Vincenzi, Fabrizio; Varani, Katia; Ramunno, Anna; Brogi, Simone; Butini, Stefania; Gemma, Sandra; Kennedy, Breandán N.; Gargini, Claudia; Strettoi, Enrica; Campiani, Giuseppe
The novel potent multidrug resistance inhibitors N,N-bis(cyclohexanol)amine aryl esters are devoid of vascular effects
2011-01-01 Saponara, Simona; Gorelli, B; Tzankova, V; Martelli, C; Teodori, E; Sgaragli, G; Fusi, Fabio
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 3,5-dibenzoyl-4-(3-phenoxyphenyl)-1,4-dihydro-2,6-dimethylpyridine (DP7): a new multidrug resistance inhibitor devoid of effects on Langendorff-perfused rat heart | 1-gen-2007 | Saponara, Simona; Ferrara, A; Gorelli, B; Shah, A; Kawase, M; Motohashi, N; Molnar, J; Sgaragli, GIAN PIETRO; Fusi, Fabio | - | |
| Antihypertensive, cardio-and neuroprotective effects of Tenebrio molitor (Coleoptera: Tenebrionidae) defatted larvae in spontaneously hypertensive rats | 1-gen-2020 | Pessina, F.; Frosini, M.; Marcolongo, P.; Fusi, F.; Saponara, S.; Gamberucci, A.; Valoti, M.; Giustarini, D.; Fiorenzani, P.; Gorelli, B.; Francardi, V.; Botta, M.; Dreassi, E. | - | |
| Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues | 1-gen-2018 | Vallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita; Chemi, Giulia; Alfano, Gloria; Lamponi, Stefania; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania | - | |
| Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability | 1-gen-2022 | Federico, S.; Khan, T.; Fontana, A.; Brogi, S.; Benedetti, R.; Sarno, F.; Carullo, G.; Pezzotta, A.; Saraswati, A. P.; Passaro, E.; Pozzetti, L.; Papa, A.; Relitti, N.; Gemma, S.; Butini, S.; Pistocchi, A.; Ramunno, A.; Vincenzi, F.; Varani, K.; Tatangelo, V.; Patrussi, L.; Baldari, C. T.; Saponara, S.; Gorelli, B.; Lamponi, S.; Valoti, M.; Saccoccia, F.; Giannaccari, M.; Ruberti, G.; Herp, D.; Jung, M.; Altucci, L.; Campiani, G. | - | |
| Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain | 1-gen-2016 | Brindisi, Margherita; Maramai, Samuele; Gemma, Sandra; Brogi, Simone; Grillo, Alessandro; Di Cesare Mannelli, Lorenzo; Gabellieri, Emanuele; Lamponi, Stefania; Saponara, Simona; Gorelli, Beatrice; Tedesco, Daniele; Bonfiglio, Tommaso; Landry, Christophe; Jung, Kwang Mook; Armirotti, Andrea; Luongo, Livio; Ligresti, Alessia; Piscitelli, Fabiana; Bertucci, Carlo; Dehouck, Marie Pierre; Campiani, Giuseppe; Maione, Sabatino; Ghelardini, Carla; Pittaluga, Anna; Piomelli, Daniele; Di Marzo, Vincenzo; Butini, Stefania | - | |
| Development of potent and selective FAAH inhibitors with improved drug-like properties as potential tools to treat neuroinflammatory conditions | 1-gen-2023 | Papa, Alessandro; Pasquini, Silvia; Galvani, Francesca; Cammarota, Mariarosaria; Contri, Chiara; Carullo, Gabriele; Gemma, Sandra; Ramunno, Anna; Lamponi, Stefania; Gorelli, Beatrice; Saponara, Simona; Varani, Katia; Mor, Marco; Campiani, Giuseppe; Boscia, Francesca; Vincenzi, Fabrizio; Lodola, Alessio; Butini, Stefania | - | |
| Effects of Autologous, Cross-Linked Erythrocytes on Isolated Hypoperfused Rabbit Heart Dynamics | 1-gen-2012 | Frosini, Maria; Larini, Alessandra; Ricci, Lorenzo; Lucas, L; Gorelli, Beatrice; Sgaragli, GIAN PIETRO; Tanganelli, Piero; Valoti, Massimo | - | |
| Harnessing the role of HDAC6 in Idiopathic Pulmonary Fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors | 1-gen-2021 | Campiani, Giuseppe; Cavella, Caterina; Osko, Jeremy D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach, Katy M; Altucci, Lucia; Bradding, Peter; Christianson, David W; Gemma, Sandra; Prasse, Antje | - | |
| MC225, a novel probe for P-glycoprotein PET Imaging at the blood-brain barrier: in vitro cardiovascular safety evaluation | 1-gen-2017 | Fusi, Fabio; Durante, Miriam; Gorelli, Beatrice; Perrone, Maria Grazia; Colabufo, Nicola Antonio; Saponara, Simona | - | |
| Negative chronotropism, positive inotropism and lusitropism of 3,5-di-t-butyl-4-hydroxyanisole (DTBHA) on rat heart preparations occur through reduction of RyR2 Ca2+ leak | 1-gen-2018 | Pessina, Federica; Gamberucci, Alessandra; Chen, Jialin; Liu, Boyin; Vangheluwe, Peter; Gorelli, Beatrice; Lorenzini, Stefania; Spiga, Ottavia; Trezza, Alfonso; Sgaragli, Giampietro; Saponara, Simona | - | |
| Neuroprotezione farmacologica del danno da ischemia-riperfusione nella vescica urinaria: approcci sperimentali | 1-gen-2001 | Pessina, F.; Esposito, L.; Sconza, R.; Gorelli, B.; Matteucci, G.; Sgaragli, G. P. | - | |
| Novel Labdane Diterpenes-Based Synthetic Derivatives: Identification of a Bifunctional Vasodilator That Inhibits CaV1.2 and Stimulates KCa1.1 Channels | 1-gen-2022 | Carullo, Gabriele; Saponara, Simona; Ahmed, Amer; Gorelli, Beatrice; Mazzotta, Sarah; Trezza, Alfonso; Gianibbi, Beatrice; Campiani, Giuseppe; Fusi, Fabio; Aiello, Francesca | - | |
| On the mechanisms of the antispasmodic action of some hindered phenols in rat aorta rings | 1-gen-2000 | Fusi, Fabio; Marazova, K.; Pessina, Federica; Gorelli, Beatrice; Valoti, Massimo; Frosini, Maria; Sgaragli, GIAN PIETRO | - | |
| Optimization of 4-Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure-Activity Relationships, in vivo Studies, and Preliminary Toxicity Profiling | 1-gen-2012 | Gemma, Sandra; Camodeca, Caterina; SANNA COCCONE, Salvatore; Bhupendra P., Joshi; Bernetti, Matteo; Moretti, Vittoria; Brogi, Simone; María Cruz, Bonache; Savini, Luisa; Donatella, Taramelli; Nicoletta, Basilico; Silvia, Parapini; Matthias, Rottmann; Reto, Brun; Lamponi, Stefania; Silvio, Caccia; Giovanna, Guiso; Robert, Summer; Rowena, Martin; Saponara, Simona; Gorelli, Beatrice; Ettore, Novellino; Campiani, Giuseppe; Butini, Stefania | - | |
| Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system | 1-gen-2014 | Saponara, Simona; Durante, Miriam; Frosini, Maria; Gorelli, Beatrice; Valoti, Massimo; Chegaev, K; Sgaragli, GIAN PIETRO; Fusi, Fabio | - | |
| Sdox, a H2S releasing anthracycline, with a safer profile than doxorubicin toward vasculature | 1-gen-2022 | Durante, M.; Frosini, M.; Chiaino, E.; Fusi, F.; Gamberucci, A.; Gorelli, B.; Chegaev, K.; Riganti, C.; Saponara, S. | - | |
| Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents | 1-gen-2021 | Grillo, Alessandro; Fezza, Filomena; Chemi, Giulia; Colangeli, Roberto; Brogi, Simone; Fazio, Domenico; Federico, Stefano; Papa, Alessandro; Relitti, Nicola; Di Maio, Roberto; Giorgi, Gianluca; Lamponi, Stefania; Valoti, Massimo; Gorelli, Beatrice; Saponara, Simona; Benedusi, Mascia; Pecorelli, Alessandra; Minetti, Patrizia; Valacchi, Giuseppe; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra; Maccarrone, Mauro; Di Giovanni, Giuseppe | - | |
| Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies | 1-gen-2014 | Brindisi, Margherita; Butini, Stefania; Franceschini, Silvia; Brogi, Simone; Trotta, Francesco; Sindu, Ros; Alfredo, Cagnotto; Mario, Salmona; Casagni, Alice; Andreassi, Marco; Saponara, Simona; Gorelli, Beatrice; Pia, Weikop; Mikkelsen, Jens D.; Jorgen Scheel Kruger, ; Karin Sandager Nielsen, ; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra | - | |
| Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy | 1-gen-2024 | Carullo, Gabriele; Orsini, Noemi; Piano, Ilaria; Pozzetti, Luca; Papa, Alessandro; Fontana, Anna; Napoli, Debora; Corsi, Francesca; Marco, Beatrice Di; Galante, Alessia; Marotta, Ludovica; Panzeca, Giovanna; O'Brien, Justine; Sanchez, Alicia Gomez; Doherty, Harry; Mahon, Niamh; Clarke, Leni; Contri, Chiara; Pasquini, Silvia; Gorelli, Beatrice; Saponara, Simona; Valoti, Massimo; Vincenzi, Fabrizio; Varani, Katia; Ramunno, Anna; Brogi, Simone; Butini, Stefania; Gemma, Sandra; Kennedy, Breandán N.; Gargini, Claudia; Strettoi, Enrica; Campiani, Giuseppe | - | |
| The novel potent multidrug resistance inhibitors N,N-bis(cyclohexanol)amine aryl esters are devoid of vascular effects | 1-gen-2011 | Saponara, Simona; Gorelli, B; Tzankova, V; Martelli, C; Teodori, E; Sgaragli, G; Fusi, Fabio | - |