VIGNAROLI, GIULIA
VIGNAROLI, GIULIA
A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors
2011-01-01 Rinaldi, Marta; Tintori, Cristina; Franchi, Luigi; Vignaroli, Giulia; Innitzer, A.; Massa, S.; Esté, J. A.; Gonzalo, E.; Christ, F.; Debyser, Z.; Botta, Maurizio
An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines
2013-01-01 Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M.
Arylation of 2-Furyl 4-Fluorophenyl Ketone: an extension of Heck Chemistry towards Novel Integrase Inhibitors
2010-01-01 Franchi, Luigi; Rinaldi, Marta; Vignaroli, Giulia; Innitzer, Anna; Radi, Marco; Botta, Maurizio
AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma
2020-01-01 Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio
COMPOUNDS AND USES THEREOF
2016-01-01 Botta, Maurizio; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Tintori, Cristina; Vignaroli, Giulia
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3s case
2011-01-01 Corradi, V; Mancini, M; Santucci, M. A.; Carlomagno, T; Sanfelice, D; Mori, M; Vignaroli, Giulia; Falchi, F; Manetti, Fabrizio; Botta, Maurizio; Botta, M.
CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction
2014-01-01 Zamperini, C.; Dreassi, E.; Vignaroli, G.; Radi, M.; Dragoni, S.; Schenone, S.; Musumeci, F.; Valoti, M.; Antiochia, R.; Botta, M.
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant
2013-01-01 Botta, Maurizio; Tintori, Cristina; Musumeci, F.; Brullo, C.; Zamperini, Claudio; Dreassi, Elena; Fallacara, Anna Lucis; Vignaroli, Giulia; Crespan, E.; Zanoli, S.; Laurenzana, Ilaria; Filippi, I.; Maga, G.; Schenone, S.; Angelucci, A.; Botta, M.
Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693
2014-01-01 Mori, Mattia; Vignaroli, Giulia; Cau, Ylenia; Dinić, J.; Hill, R.; Rossi, M.; Colecchia, D.; Pešić, M.; Link, W.; Chiariello, M.; Ottmann, C.; Botta, Maurizio
Exploring the chemical space around the privileged pyrazolo[3,4-d]pyrimidine scaffold: toward novel allosteric inhibitors of T315I-mutated Abl
2014-01-01 Vignaroli, Giulia; Mencarelli, M.; Sementa, Deborah; Crespan, E.; Kissova, M.; Maga, G.; Schenone, S.; Botta, Maurizio; Botta, M.
Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing
2015-01-01 Mori, Mattia; Cau, Ylenia; Vignaroli, Giulia; Laurenzana, Ilaria; Caivano, Antonella; Vullo, Daniela; Supuran, Claudiu T.; Botta, Maurizio
Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model
2017-01-01 Vignaroli, Giulia; Iovenitti, Giulia; Zamperini, Claudio; Coniglio, Federica; Calandro, Pierpaolo; Molinari, Alessio; Fallacara, ANNA LUCIA; Sartucci, Andrea; Calgani, Alessia; Colecchia, David; Mancini, Andrea; Festuccia, Claudio; Dreassi, Elena; Valoti, Massimo; Musumeci, Francesca; Chiariello, Mario; Angelucci, Adriano; Botta, Maurizio; Schenone, Silvia
Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors
2013-01-01 Vignaroli, Giulia; Zamperini, Claudio; Dreassi, Elena; Radi, Marco; Angelucci, A.; Sanità, P.; Crespan, E.; Kissova, M.; Maga, G.; Schenone, S.; Musumeci, F.; Botta, Maurizio
Small molecules modulation of 14-3-3 protein–protein interactions
2013-01-01 Mori, Mattia; Vignaroli, Giulia; Botta, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors | 1-gen-2011 | Rinaldi, Marta; Tintori, Cristina; Franchi, Luigi; Vignaroli, Giulia; Innitzer, A.; Massa, S.; Esté, J. A.; Gonzalo, E.; Christ, F.; Debyser, Z.; Botta, Maurizio | - | |
| An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines | 1-gen-2013 | Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M. | - | |
| Arylation of 2-Furyl 4-Fluorophenyl Ketone: an extension of Heck Chemistry towards Novel Integrase Inhibitors | 1-gen-2010 | Franchi, Luigi; Rinaldi, Marta; Vignaroli, Giulia; Innitzer, Anna; Radi, Marco; Botta, Maurizio | - | |
| AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma | 1-gen-2020 | Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio | - | |
| COMPOUNDS AND USES THEREOF | 1-gen-2016 | Botta, Maurizio; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Tintori, Cristina; Vignaroli, Giulia | - | |
| Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3s case | 1-gen-2011 | Corradi, V; Mancini, M; Santucci, M. A.; Carlomagno, T; Sanfelice, D; Mori, M; Vignaroli, Giulia; Falchi, F; Manetti, Fabrizio; Botta, Maurizio; Botta, M. | - | |
| CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction | 1-gen-2014 | Zamperini, C.; Dreassi, E.; Vignaroli, G.; Radi, M.; Dragoni, S.; Schenone, S.; Musumeci, F.; Valoti, M.; Antiochia, R.; Botta, M. | - | |
| Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant | 1-gen-2013 | Botta, Maurizio; Tintori, Cristina; Musumeci, F.; Brullo, C.; Zamperini, Claudio; Dreassi, Elena; Fallacara, Anna Lucis; Vignaroli, Giulia; Crespan, E.; Zanoli, S.; Laurenzana, Ilaria; Filippi, I.; Maga, G.; Schenone, S.; Angelucci, A.; Botta, M. | - | |
| Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693 | 1-gen-2014 | Mori, Mattia; Vignaroli, Giulia; Cau, Ylenia; Dinić, J.; Hill, R.; Rossi, M.; Colecchia, D.; Pešić, M.; Link, W.; Chiariello, M.; Ottmann, C.; Botta, Maurizio | - | |
| Exploring the chemical space around the privileged pyrazolo[3,4-d]pyrimidine scaffold: toward novel allosteric inhibitors of T315I-mutated Abl | 1-gen-2014 | Vignaroli, Giulia; Mencarelli, M.; Sementa, Deborah; Crespan, E.; Kissova, M.; Maga, G.; Schenone, S.; Botta, Maurizio; Botta, M. | - | |
| Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing | 1-gen-2015 | Mori, Mattia; Cau, Ylenia; Vignaroli, Giulia; Laurenzana, Ilaria; Caivano, Antonella; Vullo, Daniela; Supuran, Claudiu T.; Botta, Maurizio | - | |
| Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model | 1-gen-2017 | Vignaroli, Giulia; Iovenitti, Giulia; Zamperini, Claudio; Coniglio, Federica; Calandro, Pierpaolo; Molinari, Alessio; Fallacara, ANNA LUCIA; Sartucci, Andrea; Calgani, Alessia; Colecchia, David; Mancini, Andrea; Festuccia, Claudio; Dreassi, Elena; Valoti, Massimo; Musumeci, Francesca; Chiariello, Mario; Angelucci, Adriano; Botta, Maurizio; Schenone, Silvia | - | |
| Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors | 1-gen-2013 | Vignaroli, Giulia; Zamperini, Claudio; Dreassi, Elena; Radi, Marco; Angelucci, A.; Sanità, P.; Crespan, E.; Kissova, M.; Maga, G.; Schenone, S.; Musumeci, F.; Botta, Maurizio | - | |
| Small molecules modulation of 14-3-3 protein–protein interactions | 1-gen-2013 | Mori, Mattia; Vignaroli, Giulia; Botta, Maurizio | - |