VIGNAROLI, GIULIA
VIGNAROLI, GIULIA
A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors
2011-01-01 Rinaldi, Marta; Tintori, Cristina; Franchi, Luigi; Vignaroli, Giulia; A., Innitzer; S., Massa; J. A., Esté; E., Gonzalo; F., Christ; Z., Debyser; Botta, Maurizio
An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines
2013-01-01 Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M.
Arylation of 2-Furyl 4-Fluorophenyl Ketone: an extension of Heck Chemistry towards Novel Integrase Inhibitors
2010-01-01 Franchi, Luigi; Rinaldi, Marta; Vignaroli, Giulia; Innitzer, Anna; Radi, Marco; Botta, Maurizio
AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma
2020-01-01 Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio
COMPOUNDS AND USES THEREOF
2016-01-01 Botta, Maurizio; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Tintori, Cristina; Vignaroli, Giulia
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3s case
2011-01-01 Corradi, V; Mancini, M; SANTUCCI M., A; Carlomagno, T; Sanfelice, D; Mori, M; Vignaroli, Giulia; Falchi, F; Manetti, Fabrizio; Botta, Maurizio; Botta, M.
CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction.
2014-01-01 Zamperini, Claudio; Dreassi, Elena; Vignaroli, Giulia; Botta, Maurizio; Dragoni, S; Schenone, S; Musumeci, Francesca; Valoti, Massimo; Antiochia, R; Botta, M.
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant
2013-01-01 Botta, Maurizio; Tintori, Cristina; Musumeci, F.; Brullo, C.; Zamperini, Claudio; Dreassi, Elena; Fallacara, ANNA LUCIA; Vignaroli, Giulia; Crespan, E.; Zanoli, S.; Laurenzana, Ilaria; Filippi, I.; Maga, G.; Schenone, S.; Angelucci, A.; Botta, M.
Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693
2014-01-01 Mori, Mattia; Vignaroli, Giulia; Cau, Ylenia; Dinić, J; Hill, R; Rossi, M; Colecchia, D; Pešić, M; Link, W; Chiariello, M; Ottmann, C; Botta, Maurizio
Exploring the chemical space around the privileged pyrazolo[3,4-d]pyrimidine scaffold: toward novel allosteric inhibitors of T315I-mutated Abl.
2014-01-01 Vignaroli, Giulia; Mencarelli, M.; Sementa, Deborah; Crespan, E.; Kissova, M.; Maga, G.; Schenone, S.; Botta, Maurizio; Botta, M.
Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing
2015-01-01 Mori, Mattia; Cau, Ylenia; Vignaroli, Giulia; Laurenzana, Ilaria; Caivano, Antonella; Vullo, Daniela; Supuran, Claudiu T.; Botta, Maurizio
Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model
2017-01-01 Vignaroli, Giulia; Iovenitti, Giulia; Zamperini, Claudio; Coniglio, Federica; Calandro, Pierpaolo; Molinari, Alessio; Fallacara, ANNA LUCIA; Sartucci, Andrea; Calgani, Alessia; Colecchia, David; Mancini, Andrea; Festuccia, Claudio; Dreassi, Elena; Valoti, Massimo; Musumeci, Francesca; Chiariello, Mario; Angelucci, Adriano; Botta, Maurizio; Schenone, Silvia
Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors
2013-01-01 Vignaroli, Giulia; Zamperini, Claudio; Dreassi, Elena; Radi, Marco; Angelucci, A.; Sanità, P.; Crespan, Emmanuele; Kissova, M.; Maga, Giovanni; Schenone, S.; Musumeci, F.; Botta, Maurizio
Small molecules modulation of 14-3-3 protein–protein interactions
2013-01-01 Mori, Mattia; Vignaroli, Giulia; Botta, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A Versatile and Practical Synthesis toward the Development of Novel HIV-1 Integrase Inhibitors | 1-gen-2011 | Rinaldi, Marta; Tintori, Cristina; Franchi, Luigi; Vignaroli, Giulia; A., Innitzer; S., Massa; J. A., Esté; E., Gonzalo; F., Christ; Z., Debyser; Botta, Maurizio | - | |
| An alternative synthetic approach for the synthesis of biologically relevant 1,4-disubstituted pyrazolo[3,4-d]pyrimidines | 1-gen-2013 | Botta, Maurizio; Bernardo, Vincenzo; Vignaroli, Giulia; Brai, Annalaura; Biava, M.; Schenone, S.; Botta, M. | - | |
| Arylation of 2-Furyl 4-Fluorophenyl Ketone: an extension of Heck Chemistry towards Novel Integrase Inhibitors | 1-gen-2010 | Franchi, Luigi; Rinaldi, Marta; Vignaroli, Giulia; Innitzer, Anna; Radi, Marco; Botta, Maurizio | - | |
| AuNP Pyrazolo[3,4-d]pyrimidine Nanosystem in Combination with Radiotherapy against Glioblastoma | 1-gen-2020 | Molinari, Alessio; Iovenitti, Giulia; Mancini, Arianna; Luca Gravina, Giovanni; Chebbi, Monia; Caruana, Maura; Vignaroli, Giulia; Orofino, Francesco; Rango, Enrico; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Botta, Maurizio | - | |
| COMPOUNDS AND USES THEREOF | 1-gen-2016 | Botta, Maurizio; Angelucci, Adriano; Dreassi, Elena; Schenone, Silvia; Tintori, Cristina; Vignaroli, Giulia | - | |
| Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3s case | 1-gen-2011 | Corradi, V; Mancini, M; SANTUCCI M., A; Carlomagno, T; Sanfelice, D; Mori, M; Vignaroli, Giulia; Falchi, F; Manetti, Fabrizio; Botta, Maurizio; Botta, M. | - | |
| CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction. | 1-gen-2014 | Zamperini, Claudio; Dreassi, Elena; Vignaroli, Giulia; Botta, Maurizio; Dragoni, S; Schenone, S; Musumeci, Francesca; Valoti, Massimo; Antiochia, R; Botta, M. | - | |
| Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant | 1-gen-2013 | Botta, Maurizio; Tintori, Cristina; Musumeci, F.; Brullo, C.; Zamperini, Claudio; Dreassi, Elena; Fallacara, ANNA LUCIA; Vignaroli, Giulia; Crespan, E.; Zanoli, S.; Laurenzana, Ilaria; Filippi, I.; Maga, G.; Schenone, S.; Angelucci, A.; Botta, M. | - | |
| Discovery of 14-3-3 Protein-Protein Interaction Inhibitors that Sensitize Multidrug-Resistant Cancer Cells to Doxorubicin and the Akt Inhibitor GSK690693 | 1-gen-2014 | Mori, Mattia; Vignaroli, Giulia; Cau, Ylenia; Dinić, J; Hill, R; Rossi, M; Colecchia, D; Pešić, M; Link, W; Chiariello, M; Ottmann, C; Botta, Maurizio | - | |
| Exploring the chemical space around the privileged pyrazolo[3,4-d]pyrimidine scaffold: toward novel allosteric inhibitors of T315I-mutated Abl. | 1-gen-2014 | Vignaroli, Giulia; Mencarelli, M.; Sementa, Deborah; Crespan, E.; Kissova, M.; Maga, G.; Schenone, S.; Botta, Maurizio; Botta, M. | - | |
| Hit Recycling: Discovery of a Potent Carbonic Anhydrase Inhibitor by in Silico Target Fishing | 1-gen-2015 | Mori, Mattia; Cau, Ylenia; Vignaroli, Giulia; Laurenzana, Ilaria; Caivano, Antonella; Vullo, Daniela; Supuran, Claudiu T.; Botta, Maurizio | - | |
| Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model | 1-gen-2017 | Vignaroli, Giulia; Iovenitti, Giulia; Zamperini, Claudio; Coniglio, Federica; Calandro, Pierpaolo; Molinari, Alessio; Fallacara, ANNA LUCIA; Sartucci, Andrea; Calgani, Alessia; Colecchia, David; Mancini, Andrea; Festuccia, Claudio; Dreassi, Elena; Valoti, Massimo; Musumeci, Francesca; Chiariello, Mario; Angelucci, Adriano; Botta, Maurizio; Schenone, Silvia | - | |
| Pyrazolo[3,4-d]pyrimidine Prodrugs: Strategic Optimization of the Aqueous Solubility of Dual Src/Abl Inhibitors | 1-gen-2013 | Vignaroli, Giulia; Zamperini, Claudio; Dreassi, Elena; Radi, Marco; Angelucci, A.; Sanità, P.; Crespan, Emmanuele; Kissova, M.; Maga, Giovanni; Schenone, S.; Musumeci, F.; Botta, Maurizio | - | |
| Small molecules modulation of 14-3-3 protein–protein interactions | 1-gen-2013 | Mori, Mattia; Vignaroli, Giulia; Botta, Maurizio | - |