POZZI, CECILIA
POZZI, CECILIA
Dipartimento di Biotecnologie, Chimica e Farmacia
1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors
2022-01-01 Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François
1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity
2021-01-01 Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent
2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives
2013-01-01 Ferrari, Stefania; Calò, Samuele; Leone, Rosalida; Luciani, Rosaria; Costantino, Luca; Sammak, Susan; DI PISA, Flavio; Pozzi, Cecilia; Mangani, Stefano; Costi, M. Paola
4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors
2020-01-01 Gavara, L.; Sevaille, L.; De Luca, F.; Mercuri, P.; Bebrone, C.; Feller, G.; Legru, A.; Cerboni, G.; Tanfoni, S.; Baud, D.; Cutolo, G.; Bestgen, B.; Chelini, G.; Verdirosa, F.; Sannio, F.; Pozzi, C.; Benvenuti, M.; Kwapien, K.; Fischer, M.; Becker, K.; Frere, J. -M.; Mangani, S.; Gresh, N.; Berthomieu, D.; Galleni, M.; Docquier, Jd; Hernandez, J. -F.
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
2019-01-01 Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease
2018-01-01 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Costi, MARIA PAOLA; Mangani, Stefano
Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease
2018-01-01 Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae
2020-01-01 Davies, D. T.; Leiris, S.; Sprynski, N.; Castandet, J.; Lozano, C.; Bousquet, J.; Zalacain, M.; Vasa, S.; Dasari, P. K.; Pattipati, R.; Vempala, N.; Gujjewar, S.; Godi, S.; Jallala, R.; Sathyap, R. R.; Darshanoju, N. A.; Ravu, V. R.; Juventhala, R. R.; Pottabathini, N.; Sharma, S.; Pothukanuri, S.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Mangani, S.; Docquier, J. D.; Lemonnier, M.; Everett, M.
Assembly of a Functional Triiron(III) Cluster in L-Ferritin
2018-01-01 Ciambellotti, Silvia; Pozzi, Cecilia; Mangani, Stefano; Turano, Paola
Assisted assembly and growth of iron-oxide mineral particles in human L-ferritin, new insight to unveil the biomineralization process
2019-01-01 Pozzi, Cecilia; Ciambellotti, Silvia; Turano, Paola; Mangani, Stefano
Assisted assembly of a (µ3-oxo)-tris(µ2-peroxo)triiron(III) cluster in L-ferritins and its functional significance.
2017-01-01 Pozzi, Cecilia; Ciambellotti, Silvia; Bernacchioni, Caterina; DI PISA, Flavio; Turano, Paola; Mangani, Stefano
Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam
2018-01-01 Pozzi, Cecilia; Di Pisa, Flavio; De Luca, Filomena; Benvenuti, Manuela; Docquier, Jean Denis; Mangani, Stefano
Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design
2018-01-01 Di Pisa, Flavio; Pozzi, Cecilia; Benvenuti, Manuela; Docquier, Jean-Denis; De Luca, Filomena; Mangani, Stefano
Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ3-oxo)Tris[(μ2-peroxo)] triiron(III) cluster
2017-01-01 Pozzi, Cecilia; Ciambellotti, Silvia; Bernacchioni, Caterina; DI PISA, Flavio; Mangani, Stefano; Turano, Paola
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity
2017-01-01 DI PISA, Flavio; Landi, Giacomo; DELLO IACONO, Lucia; Pozzi, Cecilia; Borsari, Chiara; Ferrari, Stefania; Santucci, Matteo; Santarem, Nuno; Cordeiro Da Silva, Anabela; Moraes, Carolina B.; Alcantara, Laura M.; Fontana, Vanessa; Freitas Junior, Lucio H.; Gul, Sheraz; Kuzikov, Maria; Behrens, Birte; Pöhner, Ina; Wade, Rebecca C.; Costi, Maria Paola; Mangani, Stefano
CRYSTAL STRUCTURE OF A COMPLEX OF THYMIDYLATE SYNTHASE (TS) WITH A LIGAND
2011-01-01 Pozzi, Cecilia; Mangani, Stefano; Costi, MARIA PAOLA; Ferrari, Stefania; Guaitoli, Giambattista
Crystal structure of Enterococcus faecalis Thymidylate synthase
2010-01-01 Pozzi, Cecilia; Benvenuti, Manuela; Ferrari, Stefania; Luciani, Rosaria; Catalano, Alessia; Stroud Robert, M.; Costi Maria, Paola; Mangani, Stefano
Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam.
2013-01-01 Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, L.; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem
2016-01-01 Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS
Crystallographic studies of new human Thymidylate synthase inhibitors
2008-01-01 Pozzi, Cecilia; Guaitoli, Giambattista; Benvenuti, Manuela; Mangani, Stefano; Costi Maria, Paola
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors | 1-gen-2022 | Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François | - | |
| 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity | 1-gen-2021 | Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent | - | |
| 2'-Deoxyuridine 5'-monophosphate substrate displacement in thymidylate synthase through 6-hydroxy-2H-naphtho[1,8-bc]furan-2-one derivatives | 1-gen-2013 | Ferrari, Stefania; Calò, Samuele; Leone, Rosalida; Luciani, Rosaria; Costantino, Luca; Sammak, Susan; DI PISA, Flavio; Pozzi, Cecilia; Mangani, Stefano; Costi, M. Paola | - | |
| 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors | 1-gen-2020 | Gavara, L.; Sevaille, L.; De Luca, F.; Mercuri, P.; Bebrone, C.; Feller, G.; Legru, A.; Cerboni, G.; Tanfoni, S.; Baud, D.; Cutolo, G.; Bestgen, B.; Chelini, G.; Verdirosa, F.; Sannio, F.; Pozzi, C.; Benvenuti, M.; Kwapien, K.; Fischer, M.; Becker, K.; Frere, J. -M.; Mangani, S.; Gresh, N.; Berthomieu, D.; Galleni, M.; Docquier, Jd; Hernandez, J. -F. | - | |
| Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform | 1-gen-2019 | Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz | - | |
| Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase for the treatment of Alzheimer disease | 1-gen-2018 | Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Costi, MARIA PAOLA; Mangani, Stefano | - | |
| Amino-thiadiazole as innovative inhibitors of human glutaminyl cyclase, a validated target towards Alzheimer disease | 1-gen-2018 | Pozzi, Cecilia; Tassone, Giusy; Linciano, Pasquale; Benvenuti, Manuela; Costi, MARIA PAOLA; Mangani, Stefano | - | |
| ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae | 1-gen-2020 | Davies, D. T.; Leiris, S.; Sprynski, N.; Castandet, J.; Lozano, C.; Bousquet, J.; Zalacain, M.; Vasa, S.; Dasari, P. K.; Pattipati, R.; Vempala, N.; Gujjewar, S.; Godi, S.; Jallala, R.; Sathyap, R. R.; Darshanoju, N. A.; Ravu, V. R.; Juventhala, R. R.; Pottabathini, N.; Sharma, S.; Pothukanuri, S.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Mangani, S.; Docquier, J. D.; Lemonnier, M.; Everett, M. | - | |
| Assembly of a Functional Triiron(III) Cluster in L-Ferritin | 1-gen-2018 | Ciambellotti, Silvia; Pozzi, Cecilia; Mangani, Stefano; Turano, Paola | - | |
| Assisted assembly and growth of iron-oxide mineral particles in human L-ferritin, new insight to unveil the biomineralization process | 1-gen-2019 | Pozzi, Cecilia; Ciambellotti, Silvia; Turano, Paola; Mangani, Stefano | - | |
| Assisted assembly of a (µ3-oxo)-tris(µ2-peroxo)triiron(III) cluster in L-ferritins and its functional significance. | 1-gen-2017 | Pozzi, Cecilia; Ciambellotti, Silvia; Bernacchioni, Caterina; DI PISA, Flavio; Turano, Paola; Mangani, Stefano | - | |
| Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam | 1-gen-2018 | Pozzi, Cecilia; Di Pisa, Flavio; De Luca, Filomena; Benvenuti, Manuela; Docquier, Jean Denis; Mangani, Stefano | - | |
| Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design | 1-gen-2018 | Di Pisa, Flavio; Pozzi, Cecilia; Benvenuti, Manuela; Docquier, Jean-Denis; De Luca, Filomena; Mangani, Stefano | - | |
| Chemistry at the protein-mineral interface in L-ferritin assists the assembly of a functional (μ3-oxo)Tris[(μ2-peroxo)] triiron(III) cluster | 1-gen-2017 | Pozzi, Cecilia; Ciambellotti, Silvia; Bernacchioni, Caterina; DI PISA, Flavio; Mangani, Stefano; Turano, Paola | - | |
| Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity | 1-gen-2017 | DI PISA, Flavio; Landi, Giacomo; DELLO IACONO, Lucia; Pozzi, Cecilia; Borsari, Chiara; Ferrari, Stefania; Santucci, Matteo; Santarem, Nuno; Cordeiro Da Silva, Anabela; Moraes, Carolina B.; Alcantara, Laura M.; Fontana, Vanessa; Freitas Junior, Lucio H.; Gul, Sheraz; Kuzikov, Maria; Behrens, Birte; Pöhner, Ina; Wade, Rebecca C.; Costi, Maria Paola; Mangani, Stefano | - | |
| CRYSTAL STRUCTURE OF A COMPLEX OF THYMIDYLATE SYNTHASE (TS) WITH A LIGAND | 1-gen-2011 | Pozzi, Cecilia; Mangani, Stefano; Costi, MARIA PAOLA; Ferrari, Stefania; Guaitoli, Giambattista | - | |
| Crystal structure of Enterococcus faecalis Thymidylate synthase | 1-gen-2010 | Pozzi, Cecilia; Benvenuti, Manuela; Ferrari, Stefania; Luciani, Rosaria; Catalano, Alessia; Stroud Robert, M.; Costi Maria, Paola; Mangani, Stefano | - | |
| Crystal structure of the extended-spectrum β-lactamase BEL-1, in native form and in complex with imipenem and moxalactam. | 1-gen-2013 | Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, L.; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem | 1-gen-2016 | Pozzi, Cecilia; DE LUCA, Filomena; Benvenuti, Manuela; Poirel, Laurent; Nordmann, Patrice; Rossolini, GIAN MARIA; Mangani, Stefano; Docquier, JEAN DENIS | - | |
| Crystallographic studies of new human Thymidylate synthase inhibitors | 1-gen-2008 | Pozzi, Cecilia; Guaitoli, Giambattista; Benvenuti, Manuela; Mangani, Stefano; Costi Maria, Paola | - |