MARAMAI, SAMUELE
MARAMAI, SAMUELE
Dipartimento di Biotecnologie, Chimica e Farmacia
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation
2018-01-01 Brogi, Simone; Brindisi, Margherita; Butini, Stefania; Kshirsagar, Giridhar U.; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S.
2-hydroxy-4-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl(E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: synthesis, in silico analysis and in vitro pharmacological evaluation
2021-01-01 Brizzi, A.; Trezza, A.; Spiga, O.; Maramai, S.; Scorzelli, F.; Saponara, S.; Fusi, F.
A stereoselective approach to peptidomimetic BACE1 inhibitors
2013-01-01 Butini, Stefania; Emanuele, Gabellieri; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Egeria, Guarino; Brogi, Simone; Valeria La, Pietra; Mariateresa, Giustiniano; Luciana, Marinelli; Ettore, Novellino; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra
Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation
2017-01-01 Brogi, Simone; Maramai, Samuele; Brindisi, Margherita; Chemi, Giulia; Porcari, Valentina; Corallo, Claudio; Gennari, Luigi; Novellino, Ettore; Ramunno, Anna; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra
An Intramolecular Hydroaminomethylation-Based Approach to Pyrrolizidine Alkaloids under Microwave-Assisted Heating
2022-01-01 Petricci, Elena; Zurzolo, Simone; Matassini, Camilla; Maramai, Samuele; Cardona, Francesca; Goti, Andrea; Taddei, Maurizio
CHAPTER 18. Microwave Irradiation
2021-01-01 Maramai, Samuele; Taddei, Maurizio
Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors
2022-01-01 Paolino, Marco; Rullo, Mariagrazia; Maramai, Samuele; de Candia, Modesto; Pisani, Leonardo; Catto, Marco; Mugnaini, Claudia; Brizzi, Antonella; Cappelli, Andrea; Olivucci, Massimo; Corelli, Federico; Altomare, Cosimo D
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain
2016-01-01 Brindisi, Margherita; Maramai, Samuele; Gemma, Sandra; Brogi, Simone; Grillo, Alessandro; Di Cesare Mannelli, Lorenzo; Gabellieri, Emanuele; Lamponi, Stefania; Saponara, Simona; Gorelli, Beatrice; Tedesco, Daniele; Bonfiglio, Tommaso; Landry, Christophe; Jung, Kwang Mook; Armirotti, Andrea; Luongo, Livio; Ligresti, Alessia; Piscitelli, Fabiana; Bertucci, Carlo; Dehouck, Marie Pierre; Campiani, Giuseppe; Maione, Sabatino; Ghelardini, Carla; Pittaluga, Anna; Piomelli, Daniele; Di Marzo, Vincenzo; Butini, Stefania
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs
2016-01-01 Brindisi, Margherita; Maramai, Samuele; Grillo, Alessandro; Brogi, Simone; Butini, Stefania; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra
Development of novel cyclic peptides as pro-apoptotic agents
2016-01-01 Brindisi, Margherita; Maramai, Samuele; Brogi, Simone; Fanigliulo, Emanuela; Butini, Stefania; Guarino, Egeria; Casagni, Alice; Lamponi, Stefania; Bonechi, Claudia; Nathwani, Seema M; Finetti, Federica; Ragonese, Francesco; Arcidiacono, Paola; Campiglia, Pietro; Valenti, Salvatore; Novellino, Ettore; Spaccapelo, Roberta; Morbidelli, Lucia; Zisterer, Daniela M; Williams, Clive D; Donati, Alessandro; Baldari, Cosima; Campiani, Giuseppe; Ulivieri, Cristina; Gemma, Sandra
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain
2018-01-01 Brindisi, Margherita; Borrelli, Giuseppe; Brogi, Simone; Grillo, Alessandro; Maramai, Samuele; Paolino, Marco; Benedusi, Mascia; Pecorelli, Alessandra; Valacchi, Giuseppe; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Allarà, Marco; Ligresti, Alessia; Minetti, Patrizia; Campiani, Giuseppe; Butini, Stefania; di Marzo, Vincenzo; Gemma, Sandra
Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases
2012-01-01 Butini, Stefania; Brindisi, Margherita; Gemma, Sandra; Patrizia, Minetti; Walter, Cabri; Grazia, Gallo; Silvia, Vincenti; Emanuela, Talamonti; Franco, Borsini; Antonio, Caprioli; maria antonietta, Stasi; stefano di, Serio; Sindu, Ros; Borrelli, Giuseppe; Maramai, Samuele; Filomena, Fezza; Campiani, Giuseppe; Mauro, Maccarrone
Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation
2014-01-01 Brogi, Simone; Butini, Stefania; Maramai, Samuele; Raffaella, Colombo; Laura, Verga; Cristina, Lanni; Ersilia De, Lorenzi; Lamponi, Stefania; Andreassi, Marco; Manuela, Bartolini; Vincenza, Andrisano; Ettore, Novellino; Campiani, Giuseppe; Brindisi, Margherita; Gemma, Sandra
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition
2016-01-01 Brindisi, Margherita; Brogi, Simone; Maramai, Samuele; Grillo, Alessandro; Borrelli, Giuseppe; Butini, Stefania; Novellino, Ettore; Allarà, Marco; Ligresti, Alessia; Campiani, Giuseppe; Di Marzo, Vincenzo; Gemma, Sandra
Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors
2021-01-01 Campiani, Giuseppe; Cavella, Caterina; Osko, Jeremy D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach, Katy M; Altucci, Lucia; Bradding, Peter; Christianson, David W; Gemma, Sandra; Prasse, Antje
Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties
2013-01-01 Butini, Stefania; Gemma, Sandra; Brindisi, Margherita; Maramai, Samuele; Patrizia, Minetti; Diana, Celona; Raffaella, Napolitano; Franco, Borsini; Walter, Cabri; Filomena, Fezza; Lucio, Merlini; Sabrina, Dallavalle; Campiani, Giuseppe; Mauro, Maccarrone
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists
2023-01-01 Romeo, Isabella; Brizzi, Antonella; Pessina, Federica; Ambrosio, Francesca Alessandra; Aiello, Francesca; Belardo, Carmela; Carullo, Gabriele; Costa, Giosuè; De Petrocellis, Luciano; Frosini, Maria; Luongo, Livio; Maramai, Samuele; Paolino, Marco; Moriello, Aniello Schiano; Mugnaini, Claudia; Scorzelli, Francesco; Maione, Sabatino; Corelli, Federico; Di Marzo, Vincenzo; Alcaro, Stefano; Artese, Anna
Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders
2022-01-01 Micheli, Laura; Maramai, Samuele; Toti, Alessandra; Ferrara, Valentina; Ciampi, Clara; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla
Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress
2022-01-01 Brizzi, Antonella; Maramai, Samuele; Aiello, Francesca; Baratto, Maria Camilla; Corelli, Federico; Mugnaini, Claudia; Paolino, Marco; Scorzelli, Francesco; Aldinucci, Carlo; De Petrocellis, Luciano; Signorini, Cinzia; Pessina, Federica
Macroreticular POLITAG-Pd(0) for the waste minimized hydrogenation/reductive amination of phenols using formic acid as hydrogen source
2022-01-01 Valentini, F.; Di Erasmo, B.; Ciancuti, C.; Rossi, S.; Maramai, S.; Taddei, M.; Vaccaro, L.
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| (S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: further exploration of bioisosteric replacements and structural and biological investigation | 1-gen-2018 | Brogi, Simone; Brindisi, Margherita; Butini, Stefania; Kshirsagar, Giridhar U.; Maramai, Samuele; Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Novellino, Ettore; Fiorenzani, Paolo; Pinassi, Jessica; Aloisi, Anna Maria; Gynther, Mikko; Venskutonytė, Raminta; Han, Liwei; Frydenvang, Karla; Kastrup, Jette Sandholm; Pickering, Darryl S. | - | |
| 2-hydroxy-4-(3,5,7-trihydroxy-4-oxo-4H-chromen-2-yl)phenyl(E)-3-(4-hydroxy-3-methoxyphenyl)acrylate: synthesis, in silico analysis and in vitro pharmacological evaluation | 1-gen-2021 | Brizzi, A.; Trezza, A.; Spiga, O.; Maramai, S.; Scorzelli, F.; Saponara, S.; Fusi, F. | - | |
| A stereoselective approach to peptidomimetic BACE1 inhibitors | 1-gen-2013 | Butini, Stefania; Emanuele, Gabellieri; Brindisi, Margherita; Giovani, Simone; Maramai, Samuele; Kshirsagar, Giridhar; Egeria, Guarino; Brogi, Simone; Valeria La, Pietra; Mariateresa, Giustiniano; Luciana, Marinelli; Ettore, Novellino; Campiani, Giuseppe; Cappelli, Andrea; Gemma, Sandra | - | |
| Activation of the Wnt pathway by small peptides: rational design, synthesis and biological evaluation | 1-gen-2017 | Brogi, Simone; Maramai, Samuele; Brindisi, Margherita; Chemi, Giulia; Porcari, Valentina; Corallo, Claudio; Gennari, Luigi; Novellino, Ettore; Ramunno, Anna; Butini, Stefania; Campiani, Giuseppe; Gemma, Sandra | - | |
| An Intramolecular Hydroaminomethylation-Based Approach to Pyrrolizidine Alkaloids under Microwave-Assisted Heating | 1-gen-2022 | Petricci, Elena; Zurzolo, Simone; Matassini, Camilla; Maramai, Samuele; Cardona, Francesca; Goti, Andrea; Taddei, Maurizio | - | |
| CHAPTER 18. Microwave Irradiation | 1-gen-2021 | Maramai, Samuele; Taddei, Maurizio | - | |
| Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors | 1-gen-2022 | Paolino, Marco; Rullo, Mariagrazia; Maramai, Samuele; de Candia, Modesto; Pisani, Leonardo; Catto, Marco; Mugnaini, Claudia; Brizzi, Antonella; Cappelli, Andrea; Olivucci, Massimo; Corelli, Federico; Altomare, Cosimo D | - | |
| Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain | 1-gen-2016 | Brindisi, Margherita; Maramai, Samuele; Gemma, Sandra; Brogi, Simone; Grillo, Alessandro; Di Cesare Mannelli, Lorenzo; Gabellieri, Emanuele; Lamponi, Stefania; Saponara, Simona; Gorelli, Beatrice; Tedesco, Daniele; Bonfiglio, Tommaso; Landry, Christophe; Jung, Kwang Mook; Armirotti, Andrea; Luongo, Livio; Ligresti, Alessia; Piscitelli, Fabiana; Bertucci, Carlo; Dehouck, Marie Pierre; Campiani, Giuseppe; Maione, Sabatino; Ghelardini, Carla; Pittaluga, Anna; Piomelli, Daniele; Di Marzo, Vincenzo; Butini, Stefania | - | |
| Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs | 1-gen-2016 | Brindisi, Margherita; Maramai, Samuele; Grillo, Alessandro; Brogi, Simone; Butini, Stefania; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra | - | |
| Development of novel cyclic peptides as pro-apoptotic agents | 1-gen-2016 | Brindisi, Margherita; Maramai, Samuele; Brogi, Simone; Fanigliulo, Emanuela; Butini, Stefania; Guarino, Egeria; Casagni, Alice; Lamponi, Stefania; Bonechi, Claudia; Nathwani, Seema M; Finetti, Federica; Ragonese, Francesco; Arcidiacono, Paola; Campiglia, Pietro; Valenti, Salvatore; Novellino, Ettore; Spaccapelo, Roberta; Morbidelli, Lucia; Zisterer, Daniela M; Williams, Clive D; Donati, Alessandro; Baldari, Cosima; Campiani, Giuseppe; Ulivieri, Cristina; Gemma, Sandra | - | |
| Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain | 1-gen-2018 | Brindisi, Margherita; Borrelli, Giuseppe; Brogi, Simone; Grillo, Alessandro; Maramai, Samuele; Paolino, Marco; Benedusi, Mascia; Pecorelli, Alessandra; Valacchi, Giuseppe; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Allarà, Marco; Ligresti, Alessia; Minetti, Patrizia; Campiani, Giuseppe; Butini, Stefania; di Marzo, Vincenzo; Gemma, Sandra | - | |
| Discovery of Potent Inhibitors of Human and Mouse Fatty Acid Amide Hydrolases | 1-gen-2012 | Butini, Stefania; Brindisi, Margherita; Gemma, Sandra; Patrizia, Minetti; Walter, Cabri; Grazia, Gallo; Silvia, Vincenti; Emanuela, Talamonti; Franco, Borsini; Antonio, Caprioli; maria antonietta, Stasi; stefano di, Serio; Sindu, Ros; Borrelli, Giuseppe; Maramai, Samuele; Filomena, Fezza; Campiani, Giuseppe; Mauro, Maccarrone | - | |
| Disease modifying anti-Alzheimer’s drugs: inhibitors of human cholinesterases interfering with β-amyloid aggregation | 1-gen-2014 | Brogi, Simone; Butini, Stefania; Maramai, Samuele; Raffaella, Colombo; Laura, Verga; Cristina, Lanni; Ersilia De, Lorenzi; Lamponi, Stefania; Andreassi, Marco; Manuela, Bartolini; Vincenza, Andrisano; Ettore, Novellino; Campiani, Giuseppe; Brindisi, Margherita; Gemma, Sandra | - | |
| Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition | 1-gen-2016 | Brindisi, Margherita; Brogi, Simone; Maramai, Samuele; Grillo, Alessandro; Borrelli, Giuseppe; Butini, Stefania; Novellino, Ettore; Allarà, Marco; Ligresti, Alessia; Campiani, Giuseppe; Di Marzo, Vincenzo; Gemma, Sandra | - | |
| Harnessing the Role of HDAC6 in Idiopathic Pulmonary Fibrosis: Design, Synthesis, Structural Analysis, and Biological Evaluation of Potent Inhibitors | 1-gen-2021 | Campiani, Giuseppe; Cavella, Caterina; Osko, Jeremy D; Brindisi, Margherita; Relitti, Nicola; Brogi, Simone; Saraswati, A Prasanth; Federico, Stefano; Chemi, Giulia; Maramai, Samuele; Carullo, Gabriele; Jaeger, Benedikt; Carleo, Alfonso; Benedetti, Rosaria; Sarno, Federica; Lamponi, Stefania; Rottoli, Paola; Bargagli, Elena; Bertucci, Carlo; Tedesco, Daniele; Herp, Daniel; Senger, Johanna; Ruberti, Giovina; Saccoccia, Fulvio; Saponara, Simona; Gorelli, Beatrice; Valoti, Massimo; Kennedy, Breándan; Sundaramurthi, Husvinee; Butini, Stefania; Jung, Manfred; Roach, Katy M; Altucci, Lucia; Bradding, Peter; Christianson, David W; Gemma, Sandra; Prasse, Antje | - | |
| Identification of a novel arylpiperazine scaffold for fatty acid amide hydrolase inhibition with improved drug disposition properties | 1-gen-2013 | Butini, Stefania; Gemma, Sandra; Brindisi, Margherita; Maramai, Samuele; Patrizia, Minetti; Diana, Celona; Raffaella, Napolitano; Franco, Borsini; Walter, Cabri; Filomena, Fezza; Lucio, Merlini; Sabrina, Dallavalle; Campiani, Giuseppe; Mauro, Maccarrone | - | |
| In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists | 1-gen-2023 | Romeo, Isabella; Brizzi, Antonella; Pessina, Federica; Ambrosio, Francesca Alessandra; Aiello, Francesca; Belardo, Carmela; Carullo, Gabriele; Costa, Giosuè; De Petrocellis, Luciano; Frosini, Maria; Luongo, Livio; Maramai, Samuele; Paolino, Marco; Moriello, Aniello Schiano; Mugnaini, Claudia; Scorzelli, Francesco; Maione, Sabatino; Corelli, Federico; Di Marzo, Vincenzo; Alcaro, Stefano; Artese, Anna | - | |
| Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders | 1-gen-2022 | Micheli, Laura; Maramai, Samuele; Toti, Alessandra; Ferrara, Valentina; Ciampi, Clara; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla | - | |
| Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress | 1-gen-2022 | Brizzi, Antonella; Maramai, Samuele; Aiello, Francesca; Baratto, Maria Camilla; Corelli, Federico; Mugnaini, Claudia; Paolino, Marco; Scorzelli, Francesco; Aldinucci, Carlo; De Petrocellis, Luciano; Signorini, Cinzia; Pessina, Federica | - | |
| Macroreticular POLITAG-Pd(0) for the waste minimized hydrogenation/reductive amination of phenols using formic acid as hydrogen source | 1-gen-2022 | Valentini, F.; Di Erasmo, B.; Ciancuti, C.; Rossi, S.; Maramai, S.; Taddei, M.; Vaccaro, L. | - |