Sfoglia per Autore
Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii
2020-01-01 Davies, D. T.; Leiris, S.; Zalacain, M.; Sprynski, N.; Castandet, J.; Bousquet, J.; Lozano, C.; Llanos, A.; Alibaud, L.; Vasa, S.; Pattipati, R.; Valige, R.; Kummari, B.; Pothukanuri, S.; De Piano, C.; Morrissey, I.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Tassone, G.; Mangani, S.; Docquier, J. D.; Pallin, D.; Elliot, R.; Lemonnier, M.; Everett, M.
Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin
2020-01-01 Ciambellotti, S.; Pozzi, C.; Mangani, S.; Turano, P.
Structural and functional characterization of new human thymidylate synthase interface variants
2019-01-01 Lopresti, L; Pozzi, C; Santucci, M; Costi, Mp; Mangani, S
Structural and functional characterization of new human thymidylate synthase interface variants
2019-01-01 Lopresti, Ludovica; Pozzi, Cecilia; Santucci, Matteo; Paola Costi, Maria; Mangani, Stefano
Assisted assembly and growth of iron-oxide mineral particles in human L-ferritin, new insight to unveil the biomineralization process
2019-01-01 Pozzi, Cecilia; Ciambellotti, Silvia; Turano, Paola; Mangani, Stefano
Structural comparison between Enterococcus faecalis and human thymidylate synthase provides hints about enzyme conformational variabilities
2019-01-01 Pozzi, C; Tassone, G; Ferrari, S; Luciani, R; Costi, Mp; Mangani, S
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
2019-01-01 Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein
2019-01-01 Tassone, Giusy; Pozzi, Cecilia; Paolino, Marco; Orlandini, Maurizio; MARIN PEREZ, MARIA DEL CARMEN; Cappelli, Andrea; Olivucci, Massimo; Mangani, Stefano
Structural characterization of a synthetic mimic of the Photoactive Yellow Protein
2019-01-01 Tassone, G; Pozzi, C; Paolino, M; Orlandini, M; MARIN PEREZ, MARIA DEL CARMEN; Cappelli, A; Olivucci, M; Mangani, S
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model
2019-01-01 Leiris, Simon; Coelho, Alicia; Castandet, Jérôme; Bayet, Maëlle; Lozano, Clarisse; Bougnon, Juliette; Bousquet, Justine; Everett, Martin; Lemonnier, Marc; Sprynski, Nicolas; Zalacain, Magdalena; Pallin, Thomas David; Cramp, Michael C.; Jennings, Neil; Raphy, Gilles; Jones, Mark W.; Pattipati, Ramesh; Shankar, Battu; Sivasubrahmanyam, Relangi; Soodhagani, Ashok K.; Juventhala, Ramakrishna R.; Pottabathini, Narender; Pothukanuri, Srinivasu; Benvenuti, Manuela; Pozzi, Cecilia; Mangani, Stefano; De Luca, Filomena; Cerboni, Giulia; Docquier, Jean-Denis; Davies, David T.
Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections
2019-01-01 Linciano, Pasquale; Pozzi, Cecilia; Iacono, Lucia Dello; di Pisa, Flavio; Landi, Giacomo; Bonucci, Alessio; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Santarem, Nuno; Baptista, Catarina; Franco, Caio; Moraes, Carolina B; Müller, Wolfgang; Wittig, Ulrike; Luciani, Rosaria; Sesenna, Antony; Quotadamo, Antonio; Ferrari, Stefania; Pöhner, Ina; Cordeiro-da-Silva, Anabela; Mangani, Stefano; Costantino, Luca; Costi, Maria Paola
Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R
2019-01-01 Pozzi, Cecilia; Lopresti, Ludovica; Santucci, Matteo; Costi, Maria Paola; Mangani, Stefano
Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini
2019-01-01 Bloch, D. N.; Kolkowska, P.; Tessari, I.; Baratto, M. C.; Sinicropi, A.; Bubacco, L.; Mangani, S.; Pozzi, C.; Valensin, D.; Miller, Y.
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)
2019-01-01 Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano
Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilities
2019-01-01 Pozzi, Cecilia; Ferrari, Stefania; Luciani, Rosaria; Tassone, Giusy; Costi, Maria Paola; Mangani, Stefano
Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)
2019-01-01 Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano
Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H′ ferritin
2019-01-01 Pozzi, Cecilia; Di Pisa, Flavio; Lalli, Daniela; Rosa, Camilla; Turano, Paola; Mangani, Stefano
Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors
2019-01-01 Landi, Giacomo; Linciano, Pasquale; Borsari, Chiara; Bertolacini, Claudia P; Moraes, Carolina B; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Costi, Maria Paola; Pozzi, Cecilia; Mangani, Stefano
Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitors
2019-01-01 Pozzi, Cecilia; Ferrari, Stefania; Luciani, Rosaria; Costi, Maria Paola; Mangani, Stefano
Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart
2018-01-01 Tassone, Giusy; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii | 1-gen-2020 | Davies, D. T.; Leiris, S.; Zalacain, M.; Sprynski, N.; Castandet, J.; Bousquet, J.; Lozano, C.; Llanos, A.; Alibaud, L.; Vasa, S.; Pattipati, R.; Valige, R.; Kummari, B.; Pothukanuri, S.; De Piano, C.; Morrissey, I.; Holden, K.; Warn, P.; Marcoccia, F.; Benvenuti, M.; Pozzi, C.; Tassone, G.; Mangani, S.; Docquier, J. D.; Pallin, D.; Elliot, R.; Lemonnier, M.; Everett, M. | - | |
| Iron Biomineral Growth from the Initial Nucleation Seed in L-Ferritin | 1-gen-2020 | Ciambellotti, S.; Pozzi, C.; Mangani, S.; Turano, P. | - | |
| Structural and functional characterization of new human thymidylate synthase interface variants | 1-gen-2019 | Lopresti, L; Pozzi, C; Santucci, M; Costi, Mp; Mangani, S | - | |
| Structural and functional characterization of new human thymidylate synthase interface variants | 1-gen-2019 | Lopresti, Ludovica; Pozzi, Cecilia; Santucci, Matteo; Paola Costi, Maria; Mangani, Stefano | - | |
| Assisted assembly and growth of iron-oxide mineral particles in human L-ferritin, new insight to unveil the biomineralization process | 1-gen-2019 | Pozzi, Cecilia; Ciambellotti, Silvia; Turano, Paola; Mangani, Stefano | - | |
| Structural comparison between Enterococcus faecalis and human thymidylate synthase provides hints about enzyme conformational variabilities | 1-gen-2019 | Pozzi, C; Tassone, G; Ferrari, S; Luciani, R; Costi, Mp; Mangani, S | - | |
| Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform | 1-gen-2019 | Moraes, Carolina B.; Witt, Gesa; Kuzikov, Maria; Ellinger, Bernhard; Calogeropoulou, Theodora; Prousis, Kyriakos C.; Mangani, Stefano; Di Pisa, Flavio; Landi, Giacomo; Iacono, Lucia Dello; Pozzi, Cecilia; Freitas-Junior, Lucio H.; dos Santos Pascoalino, Bruno; Bertolacini, Claudia P.; Behrens, Birte; Keminer, Oliver; Leu, Jennifer; Wolf, Markus; Reinshagen, Jeanette; Cordeiro-da-Silva, Anabela; Santarem, Nuno; Venturelli, Alberto; Wrigley, Stephen; Karunakaran, Deepa; Kebede, Bethlehem; Pöhner, Ina; Müller, Wolfgang; Panecka-Hofman, Joanna; Wade, Rebecca C.; Fenske, Martina; Clos, Joachim; Alunda, José María; Corral, María Jesús; Uliassi, Elisa; Bolognesi, Maria Laura; Linciano, Pasquale; Quotadamo, Antonio; Ferrari, Stefania; Santucci, Matteo; Borsari, Chiara; Costi, Maria Paola; Gul, Sheraz | - | |
| Structural characterization of a synthetic mimic of the Photoactive Yellow Protein | 1-gen-2019 | Tassone, Giusy; Pozzi, Cecilia; Paolino, Marco; Orlandini, Maurizio; MARIN PEREZ, MARIA DEL CARMEN; Cappelli, Andrea; Olivucci, Massimo; Mangani, Stefano | - | |
| Structural characterization of a synthetic mimic of the Photoactive Yellow Protein | 1-gen-2019 | Tassone, G; Pozzi, C; Paolino, M; Orlandini, M; MARIN PEREZ, MARIA DEL CARMEN; Cappelli, A; Olivucci, M; Mangani, S | - | |
| SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model | 1-gen-2019 | Leiris, Simon; Coelho, Alicia; Castandet, Jérôme; Bayet, Maëlle; Lozano, Clarisse; Bougnon, Juliette; Bousquet, Justine; Everett, Martin; Lemonnier, Marc; Sprynski, Nicolas; Zalacain, Magdalena; Pallin, Thomas David; Cramp, Michael C.; Jennings, Neil; Raphy, Gilles; Jones, Mark W.; Pattipati, Ramesh; Shankar, Battu; Sivasubrahmanyam, Relangi; Soodhagani, Ashok K.; Juventhala, Ramakrishna R.; Pottabathini, Narender; Pothukanuri, Srinivasu; Benvenuti, Manuela; Pozzi, Cecilia; Mangani, Stefano; De Luca, Filomena; Cerboni, Giulia; Docquier, Jean-Denis; Davies, David T. | - | |
| Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections | 1-gen-2019 | Linciano, Pasquale; Pozzi, Cecilia; Iacono, Lucia Dello; di Pisa, Flavio; Landi, Giacomo; Bonucci, Alessio; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Santarem, Nuno; Baptista, Catarina; Franco, Caio; Moraes, Carolina B; Müller, Wolfgang; Wittig, Ulrike; Luciani, Rosaria; Sesenna, Antony; Quotadamo, Antonio; Ferrari, Stefania; Pöhner, Ina; Cordeiro-da-Silva, Anabela; Mangani, Stefano; Costantino, Luca; Costi, Maria Paola | - | |
| Evidence of destabilization of the human thymidylate synthase (hTS) dimeric structure induced by the interface mutation Q62R | 1-gen-2019 | Pozzi, Cecilia; Lopresti, Ludovica; Santucci, Matteo; Costi, Maria Paola; Mangani, Stefano | - | |
| Fibrils of α-Synuclein Abolish the Affinity of Cu2+-Binding Site to His50 and Induce Hopping of Cu2+ Ions in the Termini | 1-gen-2019 | Bloch, D. N.; Kolkowska, P.; Tessari, I.; Baratto, M. C.; Sinicropi, A.; Bubacco, L.; Mangani, S.; Pozzi, C.; Valensin, D.; Miller, Y. | - | |
| Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) | 1-gen-2019 | Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano | - | |
| Structural comparison of enterococcus faecalis and human thymidylate synthase complexes with the substrate dUMP and its analogue FdUMP provides hints about enzyme conformational variabilities | 1-gen-2019 | Pozzi, Cecilia; Ferrari, Stefania; Luciani, Rosaria; Tassone, Giusy; Costi, Maria Paola; Mangani, Stefano | - | |
| Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS) | 1-gen-2019 | Pozzi, Cecilia; Lopresti, Ludovica; Tassone, Giusy; Mangani, Stefano | - | |
| Effect of the point mutation H54N on the ferroxidase process of Rana catesbeiana H′ ferritin | 1-gen-2019 | Pozzi, Cecilia; Di Pisa, Flavio; Lalli, Daniela; Rosa, Camilla; Turano, Paola; Mangani, Stefano | - | |
| Structural Insights into the Development of Cycloguanil Derivatives as Trypanosoma brucei Pteridine-Reductase-1 Inhibitors | 1-gen-2019 | Landi, Giacomo; Linciano, Pasquale; Borsari, Chiara; Bertolacini, Claudia P; Moraes, Carolina B; Cordeiro-da-Silva, Anabela; Gul, Sheraz; Witt, Gesa; Kuzikov, Maria; Costi, Maria Paola; Pozzi, Cecilia; Mangani, Stefano | - | |
| Structural and functional characterization of the human thymidylate synthase (hTS) interface variant R175C, new perspectives for the development of hTS inhibitors | 1-gen-2019 | Pozzi, Cecilia; Ferrari, Stefania; Luciani, Rosaria; Costi, Maria Paola; Mangani, Stefano | - | |
| Probing the role of Arg97 in the parasite Leishmania braziliensis Hsp90 through site directed mutagenesis on the human counterpart | 1-gen-2018 | Tassone, Giusy; Pozzi, Cecilia; Mangani, Stefano; Botta, Maurizio | - |
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