Sfoglia per Autore
A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor
2019-01-01 Fallacara, Anna Lucia; Zamperini, Claudio; Podolski-Renić, Ana; Dinić, Jelena; Stanković, Tijana; Stepanović, Marija; Mancini, Arianna; Rango, Enrico; Iovenitti, Giulia; Molinari, Alessio; Bugli, Francesca; Sanguinetti, Maurizio; Torelli, Riccardo; Martini, Maurizio; Maccari, Laura; Valoti, Massimo; Dreassi, Elena; Botta, Maurizio; Pešić, Milica; Schenone, Silvia
β-Naphtoflavone and Ethanol Induce Cytochrome P450 and Protect towards MPP⁺ Toxicity in Human Neuroblastoma SH-SY5Y Cells
2018-01-01 Fernandez-Abascal, Jesus; Ripullone, Mariantonia; Valeri, Aurora; Leone, Cosima; Valoti, Massimo
Gold nanoparticles potentiate CaVchannel currents in rat tail artery myocytes
2018-01-01 Fusi, Fabio; Sgaragli, Giampietro; Valoti, Massimo
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe
2018-01-01 Pietrobono, Silvia; Santini, Roberta; Gagliardi, Sinforosa; Dapporto, Francesca; Colecchia, David; Chiariello, Mario; Leone, Cosima; Valoti, Massimo; Manetti, Fabrizio; Petricci, Elena; Taddei, Maurizio; Stecca, Barbara
Folate-targeted liposomal nitrooxy-doxorubicin: an effective tool against P-glycoprotein-positive and folate receptor-positive tumors
2018-01-01 Gazzano, Elena; Rolando, Barbara; Chegaev, Konstantin; Salaroglio, Iris C.; Kopecka, Joanna; Pedrini, Isabella; Saponara, Simona; Sorge, Matteo; Buondonno, Ilaria; Stella, Barbara; Marengo, Alessandro; Valoti, Massimo; Brancaccio, Mara; Fruttero, Roberta; Gasco, Alberto; Arpicco, Silvia; Riganti, Chiara
Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine
2017-01-01 De Deurwaerdère, P; Binda, C; Corne, R; Leone, Cosima; Valeri, Aurora; Valoti, M; Ramsay, Rr; Fall, Y; Marco Contelles, J.
Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model
2017-01-01 Vignaroli, Giulia; Iovenitti, Giulia; Zamperini, Claudio; Coniglio, Federica; Calandro, Pierpaolo; Molinari, Alessio; Fallacara, ANNA LUCIA; Sartucci, Andrea; Calgani, Alessia; Colecchia, David; Mancini, Andrea; Festuccia, Claudio; Dreassi, Elena; Valoti, Massimo; Musumeci, Francesca; Chiariello, Mario; Angelucci, Adriano; Botta, Maurizio; Schenone, Silvia
In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells
2016-01-01 Tzankova, V; Doneva, N; Frosini, Maria; Valoti, Massimo; Kostova, M; Rachev, B; Todorova, D; Christova, L.
Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: Nanosystem approaches for drug delivery
2016-01-01 Vignaroli, Giulia; Calandro, Pierpaolo; Zamperini, Claudio; Coniglio, Federica; Iovenitti, Giulia; Tavanti, Matteo; Colecchia, David; Dreassi, Elena; Valoti, Massimo; Schenone, Silvia; Chiariello, Mario; Botta, Maurizio
Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses
2016-01-01 Kadioglu, Onat; Saeed, Mohamed E. M.; Valoti, Massimo; Frosini, Maria; Sgaragli, Giampietro; Efferth, Thomas
Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration
2016-01-01 Ramsay Rona, R.; Magdalena, Majekova; Milagros, Medina; Valoti, Massimo
CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction.
2014-01-01 Zamperini, Claudio; Dreassi, Elena; Vignaroli, Giulia; Botta, Maurizio; Dragoni, S; Schenone, S; Musumeci, Francesca; Valoti, Massimo; Antiochia, R; Botta, M.
Functionalized mesoporous silica nanoparticles for oral delivery of budesonide
2014-01-01 Yoncheva, K.; Popova, M.; Szegedi, A.; Mihaly, J.; Tzankov, B.; Lambov, N.; Konstantinov, S.; Tzankova, V.; Pessina, Federica; Valoti, Massimo
Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system
2014-01-01 Saponara, Simona; Durante, Miriam; Frosini, Maria; Gorelli, Beatrice; Valoti, Massimo; Chegaev, K; Sgaragli, GIAN PIETRO; Fusi, Fabio
Merging computational modelling and experimental metabolite identification for toxicity prediction
2014-01-01 Cruciani, G; Goracci, L; Valeri, Aurora; Valoti, Massimo
Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol
2013-01-01 Bechi, N.; Sorda, G.; Spagnoletti, A.; Bhattacharjee, J.; Vieira Ferro, E. A.; De Freitas Barbosa, B.; Frosini, M.; Valoti, M.; Sgaragli, G.; Ricci, L.; Ietta, F.
Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor
2013-01-01 Mugnaini, Claudia; Pedani, Valentina; Casu, Angelo; Lobina, Carla; Casti, Alberto; Maccioni, Paola; Porcu, Alessandra; Giunta, Daniela; Lamponi, Stefania; Solinas, Maurizio; Dragoni, Stefania; Valoti, Massimo; Colombo, Giancarlo; Castelli, Maria Paola; Gessa, Gian Luigi; Corelli, Federico
Gold nanoparticles uptake and cytotoxicity assessed on rat liver precision-cut slices
2012-01-01 Dragoni, Stefania; Franco, Giulia; Regoli, Marì; Bracciali, Monica; Morandi, Vittorio; Sgaragli, GIAN PIETRO; Bertelli, Eugenio; Valoti, Massimo
Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids
2012-01-01 Ricci, Lorenzo; Valoti, Massimo; Sgaragli, GIAN PIETRO; Frosini, Maria
A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury
2012-01-01 Contartese, Antonella; Valoti, Massimo; Corelli, Federico; Pasquini, Serena; Mugnaini, Claudia; Pessina, Federica; Aldinucci, Carlo; Sgaragli, GIAN PIETRO; Frosini, Maria
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| A New Strategy for Glioblastoma Treatment: In Vitro and In Vivo Preclinical Characterization of Si306, a Pyrazolo[3,4-d]Pyrimidine Dual Src/P-Glycoprotein Inhibitor | 1-gen-2019 | Fallacara, Anna Lucia; Zamperini, Claudio; Podolski-Renić, Ana; Dinić, Jelena; Stanković, Tijana; Stepanović, Marija; Mancini, Arianna; Rango, Enrico; Iovenitti, Giulia; Molinari, Alessio; Bugli, Francesca; Sanguinetti, Maurizio; Torelli, Riccardo; Martini, Maurizio; Maccari, Laura; Valoti, Massimo; Dreassi, Elena; Botta, Maurizio; Pešić, Milica; Schenone, Silvia | - | |
| β-Naphtoflavone and Ethanol Induce Cytochrome P450 and Protect towards MPP⁺ Toxicity in Human Neuroblastoma SH-SY5Y Cells | 1-gen-2018 | Fernandez-Abascal, Jesus; Ripullone, Mariantonia; Valeri, Aurora; Leone, Cosima; Valoti, Massimo | - | |
| Gold nanoparticles potentiate CaVchannel currents in rat tail artery myocytes | 1-gen-2018 | Fusi, Fabio; Sgaragli, Giampietro; Valoti, Massimo | - | |
| Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe | 1-gen-2018 | Pietrobono, Silvia; Santini, Roberta; Gagliardi, Sinforosa; Dapporto, Francesca; Colecchia, David; Chiariello, Mario; Leone, Cosima; Valoti, Massimo; Manetti, Fabrizio; Petricci, Elena; Taddei, Maurizio; Stecca, Barbara | - | |
| Folate-targeted liposomal nitrooxy-doxorubicin: an effective tool against P-glycoprotein-positive and folate receptor-positive tumors | 1-gen-2018 | Gazzano, Elena; Rolando, Barbara; Chegaev, Konstantin; Salaroglio, Iris C.; Kopecka, Joanna; Pedrini, Isabella; Saponara, Simona; Sorge, Matteo; Buondonno, Ilaria; Stella, Barbara; Marengo, Alessandro; Valoti, Massimo; Brancaccio, Mara; Fruttero, Roberta; Gasco, Alberto; Arpicco, Silvia; Riganti, Chiara | - | |
| Comparative Analysis of the Neurochemical Profile and MAO Inhibition Properties of N-(Furan-2-ylmethyl)-N-methylprop-2-yn-1-amine | 1-gen-2017 | De Deurwaerdère, P; Binda, C; Corne, R; Leone, Cosima; Valeri, Aurora; Valoti, M; Ramsay, Rr; Fall, Y; Marco Contelles, J. | - | |
| Prodrugs of pyrazolo[3,4-d]pyrimidines: from library synthesis to evaluation as potential anticancer agents in an orthotopic glioblastoma model | 1-gen-2017 | Vignaroli, Giulia; Iovenitti, Giulia; Zamperini, Claudio; Coniglio, Federica; Calandro, Pierpaolo; Molinari, Alessio; Fallacara, ANNA LUCIA; Sartucci, Andrea; Calgani, Alessia; Colecchia, David; Mancini, Andrea; Festuccia, Claudio; Dreassi, Elena; Valoti, Massimo; Musumeci, Francesca; Chiariello, Mario; Angelucci, Adriano; Botta, Maurizio; Schenone, Silvia | - | |
| In vitro cytotoxicity evaluation of functional PEG-PDMA block copolymer in liver HEPG2 cells | 1-gen-2016 | Tzankova, V; Doneva, N; Frosini, Maria; Valoti, Massimo; Kostova, M; Rachev, B; Todorova, D; Christova, L. | - | |
| Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: Nanosystem approaches for drug delivery | 1-gen-2016 | Vignaroli, Giulia; Calandro, Pierpaolo; Zamperini, Claudio; Coniglio, Federica; Iovenitti, Giulia; Tavanti, Matteo; Colecchia, David; Dreassi, Elena; Valoti, Massimo; Schenone, Silvia; Chiariello, Mario; Botta, Maurizio | - | |
| Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses | 1-gen-2016 | Kadioglu, Onat; Saeed, Mohamed E. M.; Valoti, Massimo; Frosini, Maria; Sgaragli, Giampietro; Efferth, Thomas | - | |
| Key Targets for Multi-Target Ligands Designed to Combat Neurodegeneration | 1-gen-2016 | Ramsay Rona, R.; Magdalena, Majekova; Milagros, Medina; Valoti, Massimo | - | |
| CYP-dependent metabolism of antitumor pyrazolo[3,4-d]pyrimidine derivatives is characterized by an oxidative dechlorination reaction. | 1-gen-2014 | Zamperini, Claudio; Dreassi, Elena; Vignaroli, Giulia; Botta, Maurizio; Dragoni, S; Schenone, S; Musumeci, Francesca; Valoti, Massimo; Antiochia, R; Botta, M. | - | |
| Functionalized mesoporous silica nanoparticles for oral delivery of budesonide | 1-gen-2014 | Yoncheva, K.; Popova, M.; Szegedi, A.; Mihaly, J.; Tzankov, B.; Lambov, N.; Konstantinov, S.; Tzankova, V.; Pessina, Federica; Valoti, Massimo | - | |
| Screening for potential hazard effects from multitarget anthracycline on the cardiovascular system | 1-gen-2014 | Saponara, Simona; Durante, Miriam; Frosini, Maria; Gorelli, Beatrice; Valoti, Massimo; Chegaev, K; Sgaragli, GIAN PIETRO; Fusi, Fabio | - | |
| Merging computational modelling and experimental metabolite identification for toxicity prediction | 1-gen-2014 | Cruciani, G; Goracci, L; Valeri, Aurora; Valoti, Massimo | - | |
| Toxicity assessment on trophoblast cells for some environment polluting chemicals and 17β-estradiol | 1-gen-2013 | Bechi, N.; Sorda, G.; Spagnoletti, A.; Bhattacharjee, J.; Vieira Ferro, E. A.; De Freitas Barbosa, B.; Frosini, M.; Valoti, M.; Sgaragli, G.; Ricci, L.; Ietta, F. | - | |
| Synthesis and pharmacological characterization of 2-(acylamino)thiophene derivatives as metabolically stable, orally effective, positive allosteric modulators of the GABAB receptor | 1-gen-2013 | Mugnaini, Claudia; Pedani, Valentina; Casu, Angelo; Lobina, Carla; Casti, Alberto; Maccioni, Paola; Porcu, Alessandra; Giunta, Daniela; Lamponi, Stefania; Solinas, Maurizio; Dragoni, Stefania; Valoti, Massimo; Colombo, Giancarlo; Castelli, Maria Paola; Gessa, Gian Luigi; Corelli, Federico | - | |
| Gold nanoparticles uptake and cytotoxicity assessed on rat liver precision-cut slices | 1-gen-2012 | Dragoni, Stefania; Franco, Giulia; Regoli, Marì; Bracciali, Monica; Morandi, Vittorio; Sgaragli, GIAN PIETRO; Bertelli, Eugenio; Valoti, Massimo | - | |
| Taurine-like GABA aminotransferase inhibitors prevent rabbit brain slices against oxygen-glucose deprivation-induced damage. Amino Acids | 1-gen-2012 | Ricci, Lorenzo; Valoti, Massimo; Sgaragli, GIAN PIETRO; Frosini, Maria | - | |
| A novel CB2 agonist, COR167, potently protects rat brain cortical slices against OGD and reperfusion injury | 1-gen-2012 | Contartese, Antonella; Valoti, Massimo; Corelli, Federico; Pasquini, Serena; Mugnaini, Claudia; Pessina, Federica; Aldinucci, Carlo; Sgaragli, GIAN PIETRO; Frosini, Maria | - |
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