Sfoglia per Autore
Synthesis and Pharmacological Evaluation of Potent and Highly Selective D3 Receptor Ligands: Inhibition of Cocaine-Seeking Behaviour and the Role of Dopamine D3/D2Receptors
2003-01-01 Campiani, G.; Butini, S.; Trotta, F.; Fattorusso, C.; Catalanotti, B.; Aiello, F.; Gemma, S.; Nacci, V.; Novellino, E.; Stark, J. A.; Cagnotto, A.; Fumagalli, E.; Carnovali, F.; Cervo, L.; Mennini, T.
Activation of the c-Jun NH2 Terminal Kinase (JNK) Signalling Pathway is Essential During PBOX-6-Induced Apoptosis in Chronic Myelogenous leukemia (CML) Cells
2002-01-01 MC GEE, M.; Campiani, G.; Ramunno, A.; Williams, C; Zisterer, D; Nacci, V.; Lawler, M.
Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors: Past, Present, and Future Perspectives
2002-01-01 Campiani, Giuseppe; Ramunno, Anna; Maga, Giovanni; Nacci, Vito; Fattorusso, Caterina; Catalanotti, Bruno; Morelli, Elena; Novellino, Ettore
Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral-type benzodiazepine receptors (PBR)
2002-01-01 Campiani, G.; Ramunno, A.; Fiorini, I.; Nacci, V.; Morelli, E.; Novellino, E.; Goegan, M.; Mennini, T.; Sullivan, S.; Zisterer, D. M.; Williams, C. D.
Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6
2002-01-01 Mc Gee, Margaret M.; Hyland, Edel; Campiani, Giuseppe; Ramunno, Anna; Nacci, Vito; Zisterer, Daniela M.
'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one
2002-01-01 Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Morelli, Elena; Minetti, Patrizia; Tinti, Ornella; Nacci, Vito
Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies
2002-01-01 Campiani, Giuseppe; Butini, Stefania; Gemma, Sandra; Nacci, Vito; Fattorusso, C.; Catalanotti, B.; Giorgi, Gianluca; Cagnotto, A.; Goegan, M.; Mennini, T.; Minetti, P.; DI CESARE MANNELLI, L.; Mastroianni, D.; Scafetta, N.; Galletti, B.; Stasi, M.; Castorina, M.; Pacifici, L.; Ghirardi, O.; Tinti, O.; Carminati, P.
A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents
2001-01-01 Campiani, G.; De Angelis, M.; Armaroli, S.; Fattorusso, C.; Catalanotti, B.; Ramunno, A.; Nacci, V.; Novellino, E.; Grewer, C.; Ionescu, D.; Rauen, T.; Griffiths, R.
Pyrrolo-1,5-benzoxazepines Induce Apoptosis in Chronic Myelogenous Leukemia Cells (CML) by Bypassing the Apoptotic Suppressor Bcr-Abl
2001-01-01 Mc Gee, Margaret M.; Campiani, Giuseppe; Ramunno, Anna; Fattorusso, Caterina; Nacci, Vito; Lawler, Mark; Williams, D. Clive; Zisterer, Daniela M.
Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents
2001-01-01 Zisterer, D. M.; Mcgee, M. M.; Campiani, G.; Ramunno, A.; Fattorusso, C.; Nacci, V.; Lawler, M.; Williams, D. C.
Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification of a Novel Orally Bioavailable Hydrazine-Based Antiviral Agent
2001-01-01 Campiani, Giuseppe; F., Aiello; Fabbrini, Monica; E., Morelli; A., Ramunno; S., Armaroli; Nacci, Vito; A., Garofalo; G., Greco; E., Novellino; G., Maga; S., Spadari; A., Bergamini; L., Ventura; B., Bongiovanni; M., Capozzi; F., Bolacchi; S., Marini; M., Coletta; G., Guiso; S., Caccia
The Stereoselective Targeting of a Specific Enzyme-Substrate Complex is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(-)PPO464, a Novel Generation of Non-Nucleoside Inhibitors
2001-01-01 Maga, Giovanni; Ramunno, Anna; Nacci, Vito; Locatelli, Giada A.; Spadari, Silvio; Fiorini, Isabella; Baldanti, Fausto; Paolucci, Stefania; Zavattoni, Maurizio; Bergamini, Alberto; Galletti, Bruno; Muck, Sandra; Hubscher, Ulrich; Giorgi, Gianluca; Guiso, Giovanna; Caccia, Silvio; Campiani, Giuseppe
Characterisation of 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent and subtype-selective AMPA receptor full agonist with partial desensitization properties
2001-01-01 Campiani, G.; Morelli, E.; Nacci, V.; Fattorusso, C.; Ramunno, A.; Novellino, E.; Greenwood, J.; Liljefors, T.; Griffiths, R.; Sinclair, C.; Reavy, H.; Kristensen, A. S.; Pickering, D. S.; Schousboe, A.; Cagnotto, A.; Fumagalli, E.; Mennini, T.
Pyrrolo-1,5-benzoxazepines Induce Apoptosis in HL-60, Jurkart, and Hut-78 Cells: A New Class of Apoptotic Agents
2000-01-01 Zisterer, Daniela M.; Campiani, Giuseppe; Nacci, Vito; Williams, D. Clive
Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: Synthesis and Biological Evaluation of Novel Quinoxalinylethylpyridylthioureas as Potent Antiviral Agents
2000-01-01 Campiani, G.; Fabbrini, M.; Morelli, E.; Nacci, V.; Greco, G.; Novellino, E.; Maga, G.; Spadari, S.; Bergamini, A.; Faggioli, E.; Uccella, I.; Bolacchi, F.; Marini, S.; Coletta, M.; Fracasso, C.; Caccia, S.
Polycondensed Heterocycles. Part 11: Preparation and Regioselective Reductions of 5-Phenyl-4H-pyrrolo[1,2-a][1]benzazepin-4-one
2000-01-01 Garofalo, Antonio; Ragno, Gaetano; Campiani, Giuseppe; Brizzi, Antonella; Nacci, Vito
Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity
1999-01-01 Campiani, G.; Morelli, E.; Fabbrini, M.; Nacci, V.; Greco, G.; Novellino, E.; Ramunno, A.; Maga, G.; Spadari, S.; Caliendo, G.; Bergamini, A.; Faggioli, E.; Uccella, I.; Bolacchi, F.; Marini, S.; Coletta, M.; Nacca, A.; Caccia, S.
Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies
1999-01-01 Campiani, Giuseppe; Morelli, E.; Gemma, Sandra; Nacci, Vito; Butini, Stefania; Hamon, M.; Novellino, E.; Greco, G.; Cagnotto, A.; Goegan, M.; Cervo, L.; Dalla Valle, F.; Fracasso, C.; Caccia, S.; Mennini, T.
Polycondensed heterocycles. X. A new method for the preparation of pyrrolo[2,1-c][1,4]benzothiazepines by intramolecular mitsunobu cyclisation
1999-01-01 Garofalo, Antonio; Campiani, Giuseppe; Fiorini, Isabella; Nacci, Vito
Thiazolothiazepine Inhibitors of HIV-1 Integrase
1999-01-01 Neamati, N.; Turpin, J. A.; Winslow, H. E.; Christensen, J. L.; Williamson, K.; Orr, A.; Rice, W. G.; Pommier, Y.; Garofalo, A.; Brizzi, A.; Campiani, G.; Fiorini, I.; Nacci, V.
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Synthesis and Pharmacological Evaluation of Potent and Highly Selective D3 Receptor Ligands: Inhibition of Cocaine-Seeking Behaviour and the Role of Dopamine D3/D2Receptors | 1-gen-2003 | Campiani, G.; Butini, S.; Trotta, F.; Fattorusso, C.; Catalanotti, B.; Aiello, F.; Gemma, S.; Nacci, V.; Novellino, E.; Stark, J. A.; Cagnotto, A.; Fumagalli, E.; Carnovali, F.; Cervo, L.; Mennini, T. | - | |
| Activation of the c-Jun NH2 Terminal Kinase (JNK) Signalling Pathway is Essential During PBOX-6-Induced Apoptosis in Chronic Myelogenous leukemia (CML) Cells | 1-gen-2002 | MC GEE, M.; Campiani, G.; Ramunno, A.; Williams, C; Zisterer, D; Nacci, V.; Lawler, M. | - | |
| Non-Nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors: Past, Present, and Future Perspectives | 1-gen-2002 | Campiani, Giuseppe; Ramunno, Anna; Maga, Giovanni; Nacci, Vito; Fattorusso, Caterina; Catalanotti, Bruno; Morelli, Elena; Novellino, Ettore | - | |
| Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral-type benzodiazepine receptors (PBR) | 1-gen-2002 | Campiani, G.; Ramunno, A.; Fiorini, I.; Nacci, V.; Morelli, E.; Novellino, E.; Goegan, M.; Mennini, T.; Sullivan, S.; Zisterer, D. M.; Williams, C. D. | - | |
| Caspase-3 is not essential for DNA fragmentation in MCF-7 cells during apoptosis induced by the pyrrolo-1,5-benzoxazepine, PBOX-6 | 1-gen-2002 | Mc Gee, Margaret M.; Hyland, Edel; Campiani, Giuseppe; Ramunno, Anna; Nacci, Vito; Zisterer, Daniela M. | - | |
| 'Polycondensed heterocycles. Part 12: an approach to the synthesis of 2-acetyl-1'-methyl-1,2,3,4-tetrahydrospiro[isoquinoline-1,4'-pyrrolidine]-2'-one | 1-gen-2002 | Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Morelli, Elena; Minetti, Patrizia; Tinti, Ornella; Nacci, Vito | - | |
| Pyrrolo 1,3 benzothiazepine-based Atypical Antipsychotic Agents. Synthesis, Structure-Activity Relationship, Molecular Modeling, and Biological Studies | 1-gen-2002 | Campiani, Giuseppe; Butini, Stefania; Gemma, Sandra; Nacci, Vito; Fattorusso, C.; Catalanotti, B.; Giorgi, Gianluca; Cagnotto, A.; Goegan, M.; Mennini, T.; Minetti, P.; DI CESARE MANNELLI, L.; Mastroianni, D.; Scafetta, N.; Galletti, B.; Stasi, M.; Castorina, M.; Pacifici, L.; Ghirardi, O.; Tinti, O.; Carminati, P. | - | |
| A rational approach to the design of selective substrates and potent non-transportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). New glutamate and aspartate analogues as potential neuroprotective agents | 1-gen-2001 | Campiani, G.; De Angelis, M.; Armaroli, S.; Fattorusso, C.; Catalanotti, B.; Ramunno, A.; Nacci, V.; Novellino, E.; Grewer, C.; Ionescu, D.; Rauen, T.; Griffiths, R. | - | |
| Pyrrolo-1,5-benzoxazepines Induce Apoptosis in Chronic Myelogenous Leukemia Cells (CML) by Bypassing the Apoptotic Suppressor Bcr-Abl | 1-gen-2001 | Mc Gee, Margaret M.; Campiani, Giuseppe; Ramunno, Anna; Fattorusso, Caterina; Nacci, Vito; Lawler, Mark; Williams, D. Clive; Zisterer, Daniela M. | - | |
| Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents | 1-gen-2001 | Zisterer, D. M.; Mcgee, M. M.; Campiani, G.; Ramunno, A.; Fattorusso, C.; Nacci, V.; Lawler, M.; Williams, D. C. | - | |
| Quinoxalinylethylpyridylthioureas (QXPTs) as Potent Non-nucleoside HIV-1 Reverse Transcriptase (RT) Inhibitors. Further SAR Studies and Identification of a Novel Orally Bioavailable Hydrazine-Based Antiviral Agent | 1-gen-2001 | Campiani, Giuseppe; F., Aiello; Fabbrini, Monica; E., Morelli; A., Ramunno; S., Armaroli; Nacci, Vito; A., Garofalo; G., Greco; E., Novellino; G., Maga; S., Spadari; A., Bergamini; L., Ventura; B., Bongiovanni; M., Capozzi; F., Bolacchi; S., Marini; M., Coletta; G., Guiso; S., Caccia | - | |
| The Stereoselective Targeting of a Specific Enzyme-Substrate Complex is the Molecular Mechanism for the Synergic Inhibition of HIV-1 Reverse Transcriptase by (R)-(-)PPO464, a Novel Generation of Non-Nucleoside Inhibitors | 1-gen-2001 | Maga, Giovanni; Ramunno, Anna; Nacci, Vito; Locatelli, Giada A.; Spadari, Silvio; Fiorini, Isabella; Baldanti, Fausto; Paolucci, Stefania; Zavattoni, Maurizio; Bergamini, Alberto; Galletti, Bruno; Muck, Sandra; Hubscher, Ulrich; Giorgi, Gianluca; Guiso, Giovanna; Caccia, Silvio; Campiani, Giuseppe | - | |
| Characterisation of 1H-cyclopentapyrimidine-2,4(1H,3H)-dione derivative (S)-CPW399 as a novel, potent and subtype-selective AMPA receptor full agonist with partial desensitization properties | 1-gen-2001 | Campiani, G.; Morelli, E.; Nacci, V.; Fattorusso, C.; Ramunno, A.; Novellino, E.; Greenwood, J.; Liljefors, T.; Griffiths, R.; Sinclair, C.; Reavy, H.; Kristensen, A. S.; Pickering, D. S.; Schousboe, A.; Cagnotto, A.; Fumagalli, E.; Mennini, T. | - | |
| Pyrrolo-1,5-benzoxazepines Induce Apoptosis in HL-60, Jurkart, and Hut-78 Cells: A New Class of Apoptotic Agents | 1-gen-2000 | Zisterer, Daniela M.; Campiani, Giuseppe; Nacci, Vito; Williams, D. Clive | - | |
| Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: Synthesis and Biological Evaluation of Novel Quinoxalinylethylpyridylthioureas as Potent Antiviral Agents | 1-gen-2000 | Campiani, G.; Fabbrini, M.; Morelli, E.; Nacci, V.; Greco, G.; Novellino, E.; Maga, G.; Spadari, S.; Bergamini, A.; Faggioli, E.; Uccella, I.; Bolacchi, F.; Marini, S.; Coletta, M.; Fracasso, C.; Caccia, S. | - | |
| Polycondensed Heterocycles. Part 11: Preparation and Regioselective Reductions of 5-Phenyl-4H-pyrrolo[1,2-a][1]benzazepin-4-one | 1-gen-2000 | Garofalo, Antonio; Ragno, Gaetano; Campiani, Giuseppe; Brizzi, Antonella; Nacci, Vito | - | |
| Pyrrolobenzoxazepinone Derivatives as Non-Nucleoside HIV-1 RT Inhibitors: Further Structure-Activity Relationship Studies and Identification of More Potent Broad-Spectrum HIV-1 RT Inhibitors with Antiviral Activity | 1-gen-1999 | Campiani, G.; Morelli, E.; Fabbrini, M.; Nacci, V.; Greco, G.; Novellino, E.; Ramunno, A.; Maga, G.; Spadari, S.; Caliendo, G.; Bergamini, A.; Faggioli, E.; Uccella, I.; Bolacchi, F.; Marini, S.; Coletta, M.; Nacca, A.; Caccia, S. | - | |
| Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure-Activity Relationships, and Biological Studies | 1-gen-1999 | Campiani, Giuseppe; Morelli, E.; Gemma, Sandra; Nacci, Vito; Butini, Stefania; Hamon, M.; Novellino, E.; Greco, G.; Cagnotto, A.; Goegan, M.; Cervo, L.; Dalla Valle, F.; Fracasso, C.; Caccia, S.; Mennini, T. | - | |
| Polycondensed heterocycles. X. A new method for the preparation of pyrrolo[2,1-c][1,4]benzothiazepines by intramolecular mitsunobu cyclisation | 1-gen-1999 | Garofalo, Antonio; Campiani, Giuseppe; Fiorini, Isabella; Nacci, Vito | - | |
| Thiazolothiazepine Inhibitors of HIV-1 Integrase | 1-gen-1999 | Neamati, N.; Turpin, J. A.; Winslow, H. E.; Christensen, J. L.; Williamson, K.; Orr, A.; Rice, W. G.; Pommier, Y.; Garofalo, A.; Brizzi, A.; Campiani, G.; Fiorini, I.; Nacci, V. | - |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile