Sfoglia per Autore
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain
2018-01-01 Brindisi, Margherita; Borrelli, Giuseppe; Brogi, Simone; Grillo, Alessandro; Maramai, Samuele; Paolino, Marco; Benedusi, Mascia; Pecorelli, Alessandra; Valacchi, Giuseppe; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Allarà, Marco; Ligresti, Alessia; Minetti, Patrizia; Campiani, Giuseppe; Butini, Stefania; di Marzo, Vincenzo; Gemma, Sandra
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues
2018-01-01 Vallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita; Chemi, Giulia; Alfano, Gloria; Lamponi, Stefania; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents
2018-01-01 Federico, Stefano; Khan, Tuhina; Relitti, Nicola; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
Computational tool for fast in silico evaluation of hERG K+ channel affinity
2017-01-01 Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Brogi, Simone; Butini, Stefania; Brindisi, Margherita
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs
2016-01-01 Brindisi, Margherita; Maramai, Samuele; Grillo, Alessandro; Brogi, Simone; Butini, Stefania; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis
2016-01-01 Maquiaveli, Claudia C; Lucon Júnior, João F; Brogi, Simone; Campiani, Giuseppe; Gemma, Sandra; Vieira, Paulo C; Silva, Edson R.
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases
2016-01-01 Maramai, Samuele; Gemma, Sandra; Brogi, Simone; Campiani, Giuseppe; Butini, Stefania; Stark, Holger; Brindisi, Margherita
In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors
2016-01-01 Brogi, Simone; Giovani, Simone; Brindisi, Margherita; Gemma, Sandra; Novellino, Ettore; Campiani, Giuseppe; Blackman, Michael J; Butini, Stefania
Phenylpyrrole-based HDAC inhibitors: synthesis, molecular modeling and biological studies
2016-01-01 Brindisi, Margherita; Cavella, Caterina; Brogi, Simone; Nebbioso, Angela; Senger, Johanna; Maramai, Samuele; Ciotta, Alfonso; Iside, Concetta; Butini, Stefania; Lamponi, Stefania; Novellino, Ettore; Altucci, Lucia; Jung, Manfred; Campiani, Giuseppe; Gemma, Sandra
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition
2016-01-01 Brindisi, Margherita; Brogi, Simone; Maramai, Samuele; Grillo, Alessandro; Borrelli, Giuseppe; Butini, Stefania; Novellino, Ettore; Allarà, Marco; Ligresti, Alessia; Campiani, Giuseppe; Di Marzo, Vincenzo; Gemma, Sandra
Polypharmacology of dopamine receptor ligands
2016-01-01 Butini, Stefania; Nikolic, K; Kassel, S; Brückmann, H; Filipic, S; Agbaba, D; Gemma, Sandra; Brogi, Simone; Brindisi, Margherita; Campiani, Giuseppe; Stark, H.
Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors
2015-01-01 Giovani, Simone; Penzo, Maria; Butini, Stefania; Brindisi, Margherita; Gemma, Sandra; Novellino, Ettore; Campiani, Giuseppe; Blackman, Michael J.; Brogi, Simone
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking
2015-01-01 Brindisi, Margherita; Brogi, Simone; Relitti, Nicola; Vallone, Alessandra; Butini, Stefania; Gemma, Sandra; Novellino, Ettore; Colotti, Gianni; Angiulli, Gabriella; Di Chiaro, Francesco; Fiorillo, Annarita; Ilari, Andrea; Campiani, Giuseppe
Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents
2015-01-01 Brogi, Simone; Brindisi, Margherita; Joshi, BHUPENDRA PRASAD; SANNA COCCONE, Salvatore; Parapini, Silvia; Basilico, Nicoletta; Novellino, Ettore; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania
Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer's disease
2015-01-01 Chioua, Mourad; Pérez, Marta; Bautista Aguilera, Oscar M; Yañez, Matilde; López, Manuela G; Romero, Alejandro; Cacabelos, Ramón; de la Bellacasa, Raimon Puig; Brogi, Simone; Butini, Stefania; Borrell, José I; Marco Contelles, Jose
HCV-targeted Antivirals: Current Status and Future Challenges
2014-01-01 Gemma, Sandra; Brogi, Simone; Ettore, Novellino; Campiani, Giuseppe; Giovanni, Maga; Brindisi, Margherita; Butini, Stefania
Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies
2014-01-01 Brindisi, Margherita; Butini, Stefania; Franceschini, Silvia; Brogi, Simone; Trotta, Francesco; Sindu, Ros; Alfredo, Cagnotto; Mario, Salmona; Casagni, Alice; Andreassi, Marco; Saponara, Simona; Gorelli, Beatrice; Pia, Weikop; Mikkelsen, Jens D.; Jorgen Scheel Kruger, ; Karin Sandager Nielsen, ; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra
Discovery of GPCR ligands for probing signal transduction pathways
2014-01-01 Brogi, Simone; Tafi, Andrea; Désaubry, Laurent; Nebigil, Canan
Rational design of the first difluorostatone-based PfSUB1 inhibitors
2014-01-01 Giovani, Simone; Maria, Penzo; Brogi, Simone; Brindisi, Margherita; Gemma, Sandra; Ettore, Novellino; Savini, Luisa; Michael J., Blackman; Campiani, Giuseppe; Butini, Stefania
Novel Analgesic/Anti-inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors
2013-01-01 Anzini, Maurizio; Di Capua, Angela; Valenti, Salvatore; Brogi, Simone; Rovini, Michele; Giuliani, Germano; Cappelli, Andrea; Vomero, Salvatore; Chiasserini, Luisa; Sega, Alessandro; Poce, Giovanna; Giorgi, Gianluca; Calderone, Vincenzo; Martelli, Alma; Testai, Lara; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Benetti, Veronica; Giordani, Antonio; Anzellotti, Paola; Dovizio, Melania; Patrignani, Paola; Biava, Mariangela
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain | 1-gen-2018 | Brindisi, Margherita; Borrelli, Giuseppe; Brogi, Simone; Grillo, Alessandro; Maramai, Samuele; Paolino, Marco; Benedusi, Mascia; Pecorelli, Alessandra; Valacchi, Giuseppe; Di Cesare Mannelli, Lorenzo; Ghelardini, Carla; Allarà, Marco; Ligresti, Alessia; Minetti, Patrizia; Campiani, Giuseppe; Butini, Stefania; di Marzo, Vincenzo; Gemma, Sandra | - | |
| Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]- N -[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues | 1-gen-2018 | Vallone, Alessandra; D'Alessandro, Sarah; Brogi, Simone; Brindisi, Margherita; Chemi, Giulia; Alfano, Gloria; Lamponi, Stefania; Lee, Soon Goo; Jez, Joseph M.; Koolen, Karin J. M.; Dechering, Koen J.; Saponara, Simona; Fusi, Fabio; Gorelli, Beatrice; Taramelli, Donatella; Parapini, Silvia; Caldelari, Reto; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania | - | |
| A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents | 1-gen-2018 | Federico, Stefano; Khan, Tuhina; Relitti, Nicola; Chemi, Giulia; Brindisi, Margherita; Brogi, Simone; Novellino, Ettore; Zisterer, Daniela M.; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania | - | |
| Computational tool for fast in silico evaluation of hERG K+ channel affinity | 1-gen-2017 | Chemi, Giulia; Gemma, Sandra; Campiani, Giuseppe; Brogi, Simone; Butini, Stefania; Brindisi, Margherita | - | |
| Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs | 1-gen-2016 | Brindisi, Margherita; Maramai, Samuele; Grillo, Alessandro; Brogi, Simone; Butini, Stefania; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra | - | |
| Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis | 1-gen-2016 | Maquiaveli, Claudia C; Lucon Júnior, João F; Brogi, Simone; Campiani, Giuseppe; Gemma, Sandra; Vieira, Paulo C; Silva, Edson R. | - | |
| Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases | 1-gen-2016 | Maramai, Samuele; Gemma, Sandra; Brogi, Simone; Campiani, Giuseppe; Butini, Stefania; Stark, Holger; Brindisi, Margherita | - | |
| In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors | 1-gen-2016 | Brogi, Simone; Giovani, Simone; Brindisi, Margherita; Gemma, Sandra; Novellino, Ettore; Campiani, Giuseppe; Blackman, Michael J; Butini, Stefania | - | |
| Phenylpyrrole-based HDAC inhibitors: synthesis, molecular modeling and biological studies | 1-gen-2016 | Brindisi, Margherita; Cavella, Caterina; Brogi, Simone; Nebbioso, Angela; Senger, Johanna; Maramai, Samuele; Ciotta, Alfonso; Iside, Concetta; Butini, Stefania; Lamponi, Stefania; Novellino, Ettore; Altucci, Lucia; Jung, Manfred; Campiani, Giuseppe; Gemma, Sandra | - | |
| Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition | 1-gen-2016 | Brindisi, Margherita; Brogi, Simone; Maramai, Samuele; Grillo, Alessandro; Borrelli, Giuseppe; Butini, Stefania; Novellino, Ettore; Allarà, Marco; Ligresti, Alessia; Campiani, Giuseppe; Di Marzo, Vincenzo; Gemma, Sandra | - | |
| Polypharmacology of dopamine receptor ligands | 1-gen-2016 | Butini, Stefania; Nikolic, K; Kassel, S; Brückmann, H; Filipic, S; Agbaba, D; Gemma, Sandra; Brogi, Simone; Brindisi, Margherita; Campiani, Giuseppe; Stark, H. | - | |
| Plasmodium falciparum subtilisin-like protease 1: discovery of potent difluorostatone-based inhibitors | 1-gen-2015 | Giovani, Simone; Penzo, Maria; Butini, Stefania; Brindisi, Margherita; Gemma, Sandra; Novellino, Ettore; Campiani, Giuseppe; Blackman, Michael J.; Brogi, Simone | - | |
| Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking | 1-gen-2015 | Brindisi, Margherita; Brogi, Simone; Relitti, Nicola; Vallone, Alessandra; Butini, Stefania; Gemma, Sandra; Novellino, Ettore; Colotti, Gianni; Angiulli, Gabriella; Di Chiaro, Francesco; Fiorillo, Annarita; Ilari, Andrea; Campiani, Giuseppe | - | |
| Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents | 1-gen-2015 | Brogi, Simone; Brindisi, Margherita; Joshi, BHUPENDRA PRASAD; SANNA COCCONE, Salvatore; Parapini, Silvia; Basilico, Nicoletta; Novellino, Ettore; Campiani, Giuseppe; Gemma, Sandra; Butini, Stefania | - | |
| Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer's disease | 1-gen-2015 | Chioua, Mourad; Pérez, Marta; Bautista Aguilera, Oscar M; Yañez, Matilde; López, Manuela G; Romero, Alejandro; Cacabelos, Ramón; de la Bellacasa, Raimon Puig; Brogi, Simone; Butini, Stefania; Borrell, José I; Marco Contelles, Jose | - | |
| HCV-targeted Antivirals: Current Status and Future Challenges | 1-gen-2014 | Gemma, Sandra; Brogi, Simone; Ettore, Novellino; Campiani, Giuseppe; Giovanni, Maga; Brindisi, Margherita; Butini, Stefania | - | |
| Targeting Dopamine D3and Serotonin 5-HT1Aand 5-HT2AReceptors for Developing Effective Antipsychotics: Synthesis, Biological Characterization, and Behavioral Studies | 1-gen-2014 | Brindisi, Margherita; Butini, Stefania; Franceschini, Silvia; Brogi, Simone; Trotta, Francesco; Sindu, Ros; Alfredo, Cagnotto; Mario, Salmona; Casagni, Alice; Andreassi, Marco; Saponara, Simona; Gorelli, Beatrice; Pia, Weikop; Mikkelsen, Jens D.; Jorgen Scheel Kruger, ; Karin Sandager Nielsen, ; Ettore, Novellino; Campiani, Giuseppe; Gemma, Sandra | - | |
| Discovery of GPCR ligands for probing signal transduction pathways | 1-gen-2014 | Brogi, Simone; Tafi, Andrea; Désaubry, Laurent; Nebigil, Canan | - | |
| Rational design of the first difluorostatone-based PfSUB1 inhibitors | 1-gen-2014 | Giovani, Simone; Maria, Penzo; Brogi, Simone; Brindisi, Margherita; Gemma, Sandra; Ettore, Novellino; Savini, Luisa; Michael J., Blackman; Campiani, Giuseppe; Butini, Stefania | - | |
| Novel Analgesic/Anti-inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors | 1-gen-2013 | Anzini, Maurizio; Di Capua, Angela; Valenti, Salvatore; Brogi, Simone; Rovini, Michele; Giuliani, Germano; Cappelli, Andrea; Vomero, Salvatore; Chiasserini, Luisa; Sega, Alessandro; Poce, Giovanna; Giorgi, Gianluca; Calderone, Vincenzo; Martelli, Alma; Testai, Lara; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Benetti, Veronica; Giordani, Antonio; Anzellotti, Paola; Dovizio, Melania; Patrignani, Paola; Biava, Mariangela | - |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile