Sfoglia per Autore
Standardized numbering and alignment of the KPC family of β-lactamases
2026-01-01 Brunetti, Florencia; Marshall, Steven H.; Bethel, Christopher R.; Hujer, Andrea M.; Hujer, Kristine M.; Haider, Shozeb; Bush, Karen; Bradford, Patricia A.; Kreiswirth, Barry; Spencer, James; Ishii, Yoshikazu; Docquier, Jean-Denis; Rossolini, Gian Maria; Poirel, Laurent; Perilli, Mariagrazia; Amicosante, Gianfranco; Galleni, Moreno; Vila, Alejandro J.; Gutkind, Gabriel; Palzkill, Timothy; Carattoli, Alessandra; Tooke, Catherine L.; Hinchliffe, Philip; Schofield, Christopher J.; Iorga, Bogdan I.; Naas, Thierry; Chen, Yu; Arias, Cesar; Endimiani, Andrea; Papp-Wallace, Krisztina; Shields, Ryan K.; Tamma, Pranita D.; Bonomo, Robert A.; Power, Pablo
Antibacterial PROTACs: the road ahead for next-generation antibiotics?
2026-01-01 Milelli, Andrea; Raimondi, Simone; Asgharpour, Somayeh; Docquier, Jean-Denis; Spyrakis, Francesca
Editorial: Multidrug-resistant Gram-negative bacteria in fragile hosts
2026-01-01 Montagnani, Francesca; Lombardi, Andrea; Mularoni, Alessandra; Docquier, Jean-Denis; Marchesi, Francesco
Disarming carbapenemase-producing Acinetobacter baumannii: high potency of the novel therapeutic combination of meropenem and the innovative diazabicyclooctane β-lactamase inhibitor pilabactam (formerly ANT3310)
2026-01-01 Rodríguez-Pallares, Salud; Outeda-García, Michelle; Lence, Emilio; Rodríguez-Coello, Arianna; González-Pinto, Lucía; Guijarro-Sánchez, Paula; Báez-Barroso, Gabriela Alejandra; Blanco-Martín, Tania; Vázquez-Ucha, Juan Carlos; Llanos, Agustina; Sannio, Filomena; Docquier, Jean-Denis; Morrisey, Ian; Hawser, Stephen; Zalacain, Magdalena; Lemonnier, Marc; González-Bello, Concepción; Bou, Germán; Beceiro, Alejandro; Arca-Suárez, Jorge
Oxyprenyl–chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction
2026-01-01 Marotta, Ludovica; Giammarino, Francesca Maria Pia Rita; Senenou Tambou, Brondon Brandly; Tudino, Valeria; Butini, Stefania; Broccardo, Lorenza; Cancade, Sacha Michèle Idriss; Docquier, Jean-Denis; Perego, Federica; Basilico, Nicoletta; Raffellini, Lorenzo; Gul, Sheraz; Carullo, Gabriele; Gemma, Sandra; Campiani, Giuseppe
Sustainable Joullié–Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors
2025-01-01 Alfano, Antonella Ilenia; Pelliccia, Sveva; Barone, Simona; Cutarella, Luigi; Cancade, Sacha Michèle Idriss; Baia, Valerio; Cassese, Emilia; Russomanno, Pasquale; Messano, Nicolò; Frank, Denia; Weizel, Lilia; Rotter, Marco J.; Brunst, Steffen; Wichelhaus, Thomas A.; Proschak, Ewgenij; Tedesco, Daniele; Mori, Mattia; Docquier, Jean Denis; Summa, Vincenzo; Brindisi, Margherita
SAND: a comprehensive annotation of class D β-lactamases using structural alignment-based numbering
2025-01-01 Attana, Fedaa; Kim, Soobin; Spencer, James; Iorga, Bogdan I.; Docquier, Jean-Denis; Rossolini, Gian Maria; Perilli, Mariagrazia; Amicosante, Gianfranco; Vila, Alejandro J.; Vakulenko, Sergei B.; Mobashery, Shahriar; Bradford, Patricia; Bush, Karen; Partridge, Sally R.; Hujer, Andrea M.; Hujer, Kristine M.; Bonomo, Robert A.; Haider, Shozeb
Synthesis of β-lactam-zidovudine pronucleosides as potential selective narrow-spectrum antibacterial agents
2025-01-01 Rosales-Hurtado, Miyanou; Faure, Fanny; Sannio, Filomena; Verdirosa, Federica; Feller, Georges; Carretero, Elodie; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Peyrottes, Suzanne; Docquier, Jean-Denis; Gavara, Laurent
An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library
2024-01-01 Ardino, C.; Sannio, F.; Poli, G.; Galati, S.; Dreassi, E.; Botta, L.; Docquier, J. D.; D'Agostino, I.
Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste
2024-01-01 Trezza, Alfonso; Barletta, Roberta; Geminiani, Michela; Frusciante, Luisa; Olmastroni, Tommaso; Sannio, Filomena; Docquier, Jean-Denis; Santucci, Annalisa
Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors
2024-01-01 Caburet, Jérémy; Verdirosa, Federica; Moretti, Matis; Roulier, Brayan; Simoncelli, Giorgia; Haudecoeur, Romain; Ghazi, Somayeh; Jamet, Hélène; Docquier, Jean-Denis; Boucherle, Benjamin; Peuchmaur, Marine
Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases
2024-01-01 D'Humières, Camille; Delavy, Margot; Alla, Laurie; Ichou, Farid; Gauliard, Emilie; Ghozlane, Amine; Levenez, Florence; Galleron, Nathalie; Quinquis, Benoit; Pons, Nicolas; Mullaert, Jimmy; Bridier-Nahmias, Antoine; Condamine, Bénédicte; Touchon, Marie; Rainteau, Dominique; Lamazière, Antonin; Lesnik, Philippe; Ponnaiah, Maharajah; Lhomme, Marie; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Bougnoux, Marie-Elisabeth; Tenaillon, Olivier; Magnan, Mélanie; Ruppé, Etienne; Grall, Nathalie; Duval, Xavier; Ehrlich, Dusko; Mentré, France; Denamur, Erick; Rocha, Eduardo P. C.; Le Chatelier, Emmanuelle; Burdet, Charles; PrediRes study, Group
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections
2024-01-01 Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria
2023-01-01 Bersani, Matteo; Failla, Mariacristina; Vascon, Filippo; Gianquinto, Eleonora; Bertarini, Laura; Baroni, Massimo; Cruciani, Gabriele; Verdirosa, Federica; Sannio, Filomena; Docquier, Jean-Denis; Cendron, Laura; Spyrakis, Francesca; Lazzarato, Loretta; Tondi, Donatella
Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens
2023-01-01 Dalla Torre, Chiara; Sannio, Filomena; Battistella, Mattia; Docquier, Jean-Denis; De Zotti, Marta
Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties
2023-01-01 Grazia Martina, Maria; Giammarino, Federica; Vicenti, Ilaria; Groaz, Elisabetta; Rozenski, Jef; Incerti, Matteo; Sannio, Filomena; Docquier, Jean Denis; Zazzi, Maurizio; Radi, Marco
The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas
2023-01-01 Ardino, C.; Sannio, F.; Pasero, C.; Botta, L.; Dreassi, E.; Docquier, J. D.; D'Agostino, I.
Zidovudine-β-Lactam Pronucleoside Strategy for Selective Delivery into Gram-Negative Bacteria Triggered by β-Lactamases
2023-01-01 Rosales-Hurtado, Miyanou; Sannio, Filomena; Lari, Lindita; Verdirosa, Federica; Feller, Georges; Carretero, Elodie; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Docquier, Jean-Denis; Gavara, Laurent
Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships
2023-01-01 Fantacuzzi, Marialuigia; D'Agostino, Ilaria; Carradori, Simone; Liguori, Francesco; Carta, Fabrizio; Agamennone, Mariangela; Angeli, Andrea; Sannio, Filomena; Docquier, Jean-Denis; Capasso, Clemente; Supuran, Claudiu T
Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T
2023-01-01 Martinet, Loïc; Naômé, Aymeric; Rezende, Lucas C D; Tellatin, Déborah; Pignon, Bernard; Docquier, Jean-Denis; Sannio, Filomena; Baiwir, Dominique; Mazzucchelli, Gabriel; Frédérich, Michel; Rigali, Sébastien
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Standardized numbering and alignment of the KPC family of β-lactamases | 1-gen-2026 | Brunetti, Florencia; Marshall, Steven H.; Bethel, Christopher R.; Hujer, Andrea M.; Hujer, Kristine M.; Haider, Shozeb; Bush, Karen; Bradford, Patricia A.; Kreiswirth, Barry; Spencer, James; Ishii, Yoshikazu; Docquier, Jean-Denis; Rossolini, Gian Maria; Poirel, Laurent; Perilli, Mariagrazia; Amicosante, Gianfranco; Galleni, Moreno; Vila, Alejandro J.; Gutkind, Gabriel; Palzkill, Timothy; Carattoli, Alessandra; Tooke, Catherine L.; Hinchliffe, Philip; Schofield, Christopher J.; Iorga, Bogdan I.; Naas, Thierry; Chen, Yu; Arias, Cesar; Endimiani, Andrea; Papp-Wallace, Krisztina; Shields, Ryan K.; Tamma, Pranita D.; Bonomo, Robert A.; Power, Pablo | - | |
| Antibacterial PROTACs: the road ahead for next-generation antibiotics? | 1-gen-2026 | Milelli, Andrea; Raimondi, Simone; Asgharpour, Somayeh; Docquier, Jean-Denis; Spyrakis, Francesca | - | |
| Editorial: Multidrug-resistant Gram-negative bacteria in fragile hosts | 1-gen-2026 | Montagnani, Francesca; Lombardi, Andrea; Mularoni, Alessandra; Docquier, Jean-Denis; Marchesi, Francesco | - | |
| Disarming carbapenemase-producing Acinetobacter baumannii: high potency of the novel therapeutic combination of meropenem and the innovative diazabicyclooctane β-lactamase inhibitor pilabactam (formerly ANT3310) | 1-gen-2026 | Rodríguez-Pallares, Salud; Outeda-García, Michelle; Lence, Emilio; Rodríguez-Coello, Arianna; González-Pinto, Lucía; Guijarro-Sánchez, Paula; Báez-Barroso, Gabriela Alejandra; Blanco-Martín, Tania; Vázquez-Ucha, Juan Carlos; Llanos, Agustina; Sannio, Filomena; Docquier, Jean-Denis; Morrisey, Ian; Hawser, Stephen; Zalacain, Magdalena; Lemonnier, Marc; González-Bello, Concepción; Bou, Germán; Beceiro, Alejandro; Arca-Suárez, Jorge | - | |
| Oxyprenyl–chalcones as antibacterial hits: design of experiments-optimized synthesis, antibacterial evaluation, early drug-like profiling and biodegradability prediction | 1-gen-2026 | Marotta, Ludovica; Giammarino, Francesca Maria Pia Rita; Senenou Tambou, Brondon Brandly; Tudino, Valeria; Butini, Stefania; Broccardo, Lorenza; Cancade, Sacha Michèle Idriss; Docquier, Jean-Denis; Perego, Federica; Basilico, Nicoletta; Raffellini, Lorenzo; Gul, Sheraz; Carullo, Gabriele; Gemma, Sandra; Campiani, Giuseppe | - | |
| Sustainable Joullié–Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors | 1-gen-2025 | Alfano, Antonella Ilenia; Pelliccia, Sveva; Barone, Simona; Cutarella, Luigi; Cancade, Sacha Michèle Idriss; Baia, Valerio; Cassese, Emilia; Russomanno, Pasquale; Messano, Nicolò; Frank, Denia; Weizel, Lilia; Rotter, Marco J.; Brunst, Steffen; Wichelhaus, Thomas A.; Proschak, Ewgenij; Tedesco, Daniele; Mori, Mattia; Docquier, Jean Denis; Summa, Vincenzo; Brindisi, Margherita | - | |
| SAND: a comprehensive annotation of class D β-lactamases using structural alignment-based numbering | 1-gen-2025 | Attana, Fedaa; Kim, Soobin; Spencer, James; Iorga, Bogdan I.; Docquier, Jean-Denis; Rossolini, Gian Maria; Perilli, Mariagrazia; Amicosante, Gianfranco; Vila, Alejandro J.; Vakulenko, Sergei B.; Mobashery, Shahriar; Bradford, Patricia; Bush, Karen; Partridge, Sally R.; Hujer, Andrea M.; Hujer, Kristine M.; Bonomo, Robert A.; Haider, Shozeb | - | |
| Synthesis of β-lactam-zidovudine pronucleosides as potential selective narrow-spectrum antibacterial agents | 1-gen-2025 | Rosales-Hurtado, Miyanou; Faure, Fanny; Sannio, Filomena; Verdirosa, Federica; Feller, Georges; Carretero, Elodie; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Peyrottes, Suzanne; Docquier, Jean-Denis; Gavara, Laurent | - | |
| An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library | 1-gen-2024 | Ardino, C.; Sannio, F.; Poli, G.; Galati, S.; Dreassi, E.; Botta, L.; Docquier, J. D.; D'Agostino, I. | - | |
| Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste | 1-gen-2024 | Trezza, Alfonso; Barletta, Roberta; Geminiani, Michela; Frusciante, Luisa; Olmastroni, Tommaso; Sannio, Filomena; Docquier, Jean-Denis; Santucci, Annalisa | - | |
| Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors | 1-gen-2024 | Caburet, Jérémy; Verdirosa, Federica; Moretti, Matis; Roulier, Brayan; Simoncelli, Giorgia; Haudecoeur, Romain; Ghazi, Somayeh; Jamet, Hélène; Docquier, Jean-Denis; Boucherle, Benjamin; Peuchmaur, Marine | - | |
| Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases | 1-gen-2024 | D'Humières, Camille; Delavy, Margot; Alla, Laurie; Ichou, Farid; Gauliard, Emilie; Ghozlane, Amine; Levenez, Florence; Galleron, Nathalie; Quinquis, Benoit; Pons, Nicolas; Mullaert, Jimmy; Bridier-Nahmias, Antoine; Condamine, Bénédicte; Touchon, Marie; Rainteau, Dominique; Lamazière, Antonin; Lesnik, Philippe; Ponnaiah, Maharajah; Lhomme, Marie; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Bougnoux, Marie-Elisabeth; Tenaillon, Olivier; Magnan, Mélanie; Ruppé, Etienne; Grall, Nathalie; Duval, Xavier; Ehrlich, Dusko; Mentré, France; Denamur, Erick; Rocha, Eduardo P. C.; Le Chatelier, Emmanuelle; Burdet, Charles; PrediRes study, Group | - | |
| 4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections | 1-gen-2024 | Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco | - | |
| Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria | 1-gen-2023 | Bersani, Matteo; Failla, Mariacristina; Vascon, Filippo; Gianquinto, Eleonora; Bertarini, Laura; Baroni, Massimo; Cruciani, Gabriele; Verdirosa, Federica; Sannio, Filomena; Docquier, Jean-Denis; Cendron, Laura; Spyrakis, Francesca; Lazzarato, Loretta; Tondi, Donatella | - | |
| Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens | 1-gen-2023 | Dalla Torre, Chiara; Sannio, Filomena; Battistella, Mattia; Docquier, Jean-Denis; De Zotti, Marta | - | |
| Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties | 1-gen-2023 | Grazia Martina, Maria; Giammarino, Federica; Vicenti, Ilaria; Groaz, Elisabetta; Rozenski, Jef; Incerti, Matteo; Sannio, Filomena; Docquier, Jean Denis; Zazzi, Maurizio; Radi, Marco | - | |
| The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas | 1-gen-2023 | Ardino, C.; Sannio, F.; Pasero, C.; Botta, L.; Dreassi, E.; Docquier, J. D.; D'Agostino, I. | - | |
| Zidovudine-β-Lactam Pronucleoside Strategy for Selective Delivery into Gram-Negative Bacteria Triggered by β-Lactamases | 1-gen-2023 | Rosales-Hurtado, Miyanou; Sannio, Filomena; Lari, Lindita; Verdirosa, Federica; Feller, Georges; Carretero, Elodie; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Docquier, Jean-Denis; Gavara, Laurent | - | |
| Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships | 1-gen-2023 | Fantacuzzi, Marialuigia; D'Agostino, Ilaria; Carradori, Simone; Liguori, Francesco; Carta, Fabrizio; Agamennone, Mariangela; Angeli, Andrea; Sannio, Filomena; Docquier, Jean-Denis; Capasso, Clemente; Supuran, Claudiu T | - | |
| Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T | 1-gen-2023 | Martinet, Loïc; Naômé, Aymeric; Rezende, Lucas C D; Tellatin, Déborah; Pignon, Bernard; Docquier, Jean-Denis; Sannio, Filomena; Baiwir, Dominique; Mazzucchelli, Gabriel; Frédérich, Michel; Rigali, Sébastien | - |
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