Sfoglia per Autore
Sustainable Joullié–Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors
2025-01-01 Alfano, Antonella Ilenia; Pelliccia, Sveva; Barone, Simona; Cutarella, Luigi; Cancade, Sacha Michèle Idriss; Baia, Valerio; Cassese, Emilia; Russomanno, Pasquale; Messano, Nicolò; Frank, Denia; Weizel, Lilia; Rotter, Marco J.; Brunst, Steffen; Wichelhaus, Thomas A.; Proschak, Ewgenij; Tedesco, Daniele; Mori, Mattia; Docquier, Jean Denis; Summa, Vincenzo; Brindisi, Margherita
Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors
2024-01-01 Caburet, Jérémy; Verdirosa, Federica; Moretti, Matis; Roulier, Brayan; Simoncelli, Giorgia; Haudecoeur, Romain; Ghazi, Somayeh; Jamet, Hélène; Docquier, Jean-Denis; Boucherle, Benjamin; Peuchmaur, Marine
Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases
2024-01-01 D'Humières, Camille; Delavy, Margot; Alla, Laurie; Ichou, Farid; Gauliard, Emilie; Ghozlane, Amine; Levenez, Florence; Galleron, Nathalie; Quinquis, Benoit; Pons, Nicolas; Mullaert, Jimmy; Bridier-Nahmias, Antoine; Condamine, Bénédicte; Touchon, Marie; Rainteau, Dominique; Lamazière, Antonin; Lesnik, Philippe; Ponnaiah, Maharajah; Lhomme, Marie; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Bougnoux, Marie-Elisabeth; Tenaillon, Olivier; Magnan, Mélanie; Ruppé, Etienne; Grall, Nathalie; Duval, Xavier; Ehrlich, Dusko; Mentré, France; Denamur, Erick; Rocha, Eduardo P. C.; Le Chatelier, Emmanuelle; Burdet, Charles; PrediRes study, Group
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections
2024-01-01 Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco
Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste
2024-01-01 Trezza, Alfonso; Barletta, Roberta; Geminiani, Michela; Frusciante, Luisa; Olmastroni, Tommaso; Sannio, Filomena; Docquier, Jean-Denis; Santucci, Annalisa
An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library
2024-01-01 Ardino, C.; Sannio, F.; Poli, G.; Galati, S.; Dreassi, E.; Botta, L.; Docquier, J. D.; D'Agostino, I.
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria
2023-01-01 Bersani, Matteo; Failla, Mariacristina; Vascon, Filippo; Gianquinto, Eleonora; Bertarini, Laura; Baroni, Massimo; Cruciani, Gabriele; Verdirosa, Federica; Sannio, Filomena; Docquier, Jean-Denis; Cendron, Laura; Spyrakis, Francesca; Lazzarato, Loretta; Tondi, Donatella
Discovering NDM-1 inhibitors using molecular substructure embeddings representations
2023-01-01 Papastergiou, Thomas; Azé, Jérôme; Bringay, Sandra; Louet, Maxime; Poncelet, Pascal; Rosales-Hurtado, Miyanou; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Docquier, Jean-Denis; Gavara, Laurent
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models
2023-01-01 Everett, Martin J; Davies, David T; Leiris, Simon; Sprynski, Nicolas; Llanos, Agustina; Castandet, Jérôme M; Lozano, Clarisse; Larock, Christopher N; Larock, Doris L; Corsica, Giuseppina; Docquier, Jean-Denis; Pallin, Thomas D; Cridland, Andrew; Blench, Toby; Zalacain, Magdalena; Lemonnier, Marc
Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships
2023-01-01 Fantacuzzi, Marialuigia; D'Agostino, Ilaria; Carradori, Simone; Liguori, Francesco; Carta, Fabrizio; Agamennone, Mariangela; Angeli, Andrea; Sannio, Filomena; Docquier, Jean-Denis; Capasso, Clemente; Supuran, Claudiu T
Zidovudine-β-Lactam Pronucleoside Strategy for Selective Delivery into Gram-Negative Bacteria Triggered by β-Lactamases
2023-01-01 Rosales-Hurtado, Miyanou; Sannio, Filomena; Lari, Lindita; Verdirosa, Federica; Feller, Georges; Carretero, Elodie; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Docquier, Jean-Denis; Gavara, Laurent
Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T
2023-01-01 Martinet, Loïc; Naômé, Aymeric; Rezende, Lucas C D; Tellatin, Déborah; Pignon, Bernard; Docquier, Jean-Denis; Sannio, Filomena; Baiwir, Dominique; Mazzucchelli, Gabriel; Frédérich, Michel; Rigali, Sébastien
Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties
2023-01-01 Grazia Martina, Maria; Giammarino, Federica; Vicenti, Ilaria; Groaz, Elisabetta; Rozenski, Jef; Incerti, Matteo; Sannio, Filomena; Docquier, Jean Denis; Zazzi, Maurizio; Radi, Marco
The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas
2023-01-01 Ardino, C.; Sannio, F.; Pasero, C.; Botta, L.; Dreassi, E.; Docquier, J. D.; D'Agostino, I.
Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors
2023-01-01 Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena
Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens
2023-01-01 Dalla Torre, Chiara; Sannio, Filomena; Battistella, Mattia; Docquier, Jean-Denis; De Zotti, Marta
Editorial: Structural and Biochemical Aspects of the Interaction of β-Lactamases With State-of-the-Art Inhibitors
2022-01-01 Papp-Wallace, Krisztina M; Docquier, Jean-Denis; Kerff, Frederic; Power, Pablo
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates
2022-01-01 Legru, Alice; Verdirosa, Federica; Vo-Hoang, Yen; Tassone, Giusy; Vascon, Filippo; Thomas, Caitlyn A; Sannio, Filomena; Corsica, Giuseppina; Benvenuti, Manuela; Feller, Georges; Coulon, Rémi; Marcoccia, Francesca; Devente, Savannah Rowane; Bouajila, Ezeddine; Piveteau, Catherine; Leroux, Florence; Deprez-Poulain, Rebecca; Deprez, Benoît; Licznar-Fajardo, Patricia; Crowder, Michael W; Cendron, Laura; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François; Gavara, Laurent
A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiotics
2022-01-01 Delavy, Margot; Burdet, Charles; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Grall, Nathalie; Volant, Stevenn; Ghozlane, Amine; Duval, Xavier; Mentré, France; D'Enfert, Christophe; Bougnoux, Marie-Elisabeth
1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors
2022-01-01 Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François
| Titolo | Data di pubblicazione | Autore(i) | File | Abstract |
|---|---|---|---|---|
| Sustainable Joullié–Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors | 1-gen-2025 | Alfano, Antonella Ilenia; Pelliccia, Sveva; Barone, Simona; Cutarella, Luigi; Cancade, Sacha Michèle Idriss; Baia, Valerio; Cassese, Emilia; Russomanno, Pasquale; Messano, Nicolò; Frank, Denia; Weizel, Lilia; Rotter, Marco J.; Brunst, Steffen; Wichelhaus, Thomas A.; Proschak, Ewgenij; Tedesco, Daniele; Mori, Mattia; Docquier, Jean Denis; Summa, Vincenzo; Brindisi, Margherita | - | |
| Aurones and derivatives as promising New Delhi metallo-β-lactamase (NDM-1) inhibitors | 1-gen-2024 | Caburet, Jérémy; Verdirosa, Federica; Moretti, Matis; Roulier, Brayan; Simoncelli, Giorgia; Haudecoeur, Romain; Ghazi, Somayeh; Jamet, Hélène; Docquier, Jean-Denis; Boucherle, Benjamin; Peuchmaur, Marine | - | |
| Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases | 1-gen-2024 | D'Humières, Camille; Delavy, Margot; Alla, Laurie; Ichou, Farid; Gauliard, Emilie; Ghozlane, Amine; Levenez, Florence; Galleron, Nathalie; Quinquis, Benoit; Pons, Nicolas; Mullaert, Jimmy; Bridier-Nahmias, Antoine; Condamine, Bénédicte; Touchon, Marie; Rainteau, Dominique; Lamazière, Antonin; Lesnik, Philippe; Ponnaiah, Maharajah; Lhomme, Marie; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Bougnoux, Marie-Elisabeth; Tenaillon, Olivier; Magnan, Mélanie; Ruppé, Etienne; Grall, Nathalie; Duval, Xavier; Ehrlich, Dusko; Mentré, France; Denamur, Erick; Rocha, Eduardo P. C.; Le Chatelier, Emmanuelle; Burdet, Charles; PrediRes study, Group | - | |
| 4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections | 1-gen-2024 | Barbieri, Francesca; Carlen, Vincent; Martina, Maria Grazia; Sannio, Filomena; Cancade, Sacha; Perini, Cecilia; Restori, Margherita; Crespan, Emmanuele; Maga, Giovanni; Docquier, Jean-Denis; Cagno, Valeria; Radi, Marco | - | |
| Chestnut Burrs as Natural Source of Antimicrobial Bioactive Compounds: A Valorization of Agri-Food Waste | 1-gen-2024 | Trezza, Alfonso; Barletta, Roberta; Geminiani, Michela; Frusciante, Luisa; Olmastroni, Tommaso; Sannio, Filomena; Docquier, Jean-Denis; Santucci, Annalisa | - | |
| An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library | 1-gen-2024 | Ardino, C.; Sannio, F.; Poli, G.; Galati, S.; Dreassi, E.; Botta, L.; Docquier, J. D.; D'Agostino, I. | - | |
| Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria | 1-gen-2023 | Bersani, Matteo; Failla, Mariacristina; Vascon, Filippo; Gianquinto, Eleonora; Bertarini, Laura; Baroni, Massimo; Cruciani, Gabriele; Verdirosa, Federica; Sannio, Filomena; Docquier, Jean-Denis; Cendron, Laura; Spyrakis, Francesca; Lazzarato, Loretta; Tondi, Donatella | - | |
| Discovering NDM-1 inhibitors using molecular substructure embeddings representations | 1-gen-2023 | Papastergiou, Thomas; Azé, Jérôme; Bringay, Sandra; Louet, Maxime; Poncelet, Pascal; Rosales-Hurtado, Miyanou; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Docquier, Jean-Denis; Gavara, Laurent | - | |
| Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models | 1-gen-2023 | Everett, Martin J; Davies, David T; Leiris, Simon; Sprynski, Nicolas; Llanos, Agustina; Castandet, Jérôme M; Lozano, Clarisse; Larock, Christopher N; Larock, Doris L; Corsica, Giuseppina; Docquier, Jean-Denis; Pallin, Thomas D; Cridland, Andrew; Blench, Toby; Zalacain, Magdalena; Lemonnier, Marc | - | |
| Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships | 1-gen-2023 | Fantacuzzi, Marialuigia; D'Agostino, Ilaria; Carradori, Simone; Liguori, Francesco; Carta, Fabrizio; Agamennone, Mariangela; Angeli, Andrea; Sannio, Filomena; Docquier, Jean-Denis; Capasso, Clemente; Supuran, Claudiu T | - | |
| Zidovudine-β-Lactam Pronucleoside Strategy for Selective Delivery into Gram-Negative Bacteria Triggered by β-Lactamases | 1-gen-2023 | Rosales-Hurtado, Miyanou; Sannio, Filomena; Lari, Lindita; Verdirosa, Federica; Feller, Georges; Carretero, Elodie; Vo-Hoang, Yen; Licznar-Fajardo, Patricia; Docquier, Jean-Denis; Gavara, Laurent | - | |
| Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T | 1-gen-2023 | Martinet, Loïc; Naômé, Aymeric; Rezende, Lucas C D; Tellatin, Déborah; Pignon, Bernard; Docquier, Jean-Denis; Sannio, Filomena; Baiwir, Dominique; Mazzucchelli, Gabriel; Frédérich, Michel; Rigali, Sébastien | - | |
| Nucleoside Derivatives of 2,6-Diaminopurine Antivirals: Base-Modified Nucleosides with Broad-Spectrum Antimicrobial Properties | 1-gen-2023 | Grazia Martina, Maria; Giammarino, Federica; Vicenti, Ilaria; Groaz, Elisabetta; Rozenski, Jef; Incerti, Matteo; Sannio, Filomena; Docquier, Jean Denis; Zazzi, Maurizio; Radi, Marco | - | |
| The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas | 1-gen-2023 | Ardino, C.; Sannio, F.; Pasero, C.; Botta, L.; Dreassi, E.; Docquier, J. D.; D'Agostino, I. | - | |
| Discovery and Optimization of a Novel Macrocyclic Amidinourea Series Active as Acidic Mammalian Chitinase Inhibitors | 1-gen-2023 | Balestri, Lorenzo Jacopo Ilic; Trivisani, Claudia Immacolata; Orofino, Francesco; Fiorucci, Diego; Truglio, Giuseppina Ivana; D'Agostino, Ilaria; Poggialini, Federica; Botta, Lorenzo; Docquier, Jean-Denis; Dreassi, Elena | - | |
| Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens | 1-gen-2023 | Dalla Torre, Chiara; Sannio, Filomena; Battistella, Mattia; Docquier, Jean-Denis; De Zotti, Marta | - | |
| Editorial: Structural and Biochemical Aspects of the Interaction of β-Lactamases With State-of-the-Art Inhibitors | 1-gen-2022 | Papp-Wallace, Krisztina M; Docquier, Jean-Denis; Kerff, Frederic; Power, Pablo | - | |
| Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates | 1-gen-2022 | Legru, Alice; Verdirosa, Federica; Vo-Hoang, Yen; Tassone, Giusy; Vascon, Filippo; Thomas, Caitlyn A; Sannio, Filomena; Corsica, Giuseppina; Benvenuti, Manuela; Feller, Georges; Coulon, Rémi; Marcoccia, Francesca; Devente, Savannah Rowane; Bouajila, Ezeddine; Piveteau, Catherine; Leroux, Florence; Deprez-Poulain, Rebecca; Deprez, Benoît; Licznar-Fajardo, Patricia; Crowder, Michael W; Cendron, Laura; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François; Gavara, Laurent | - | |
| A Clinical Study Provides the First Direct Evidence That Interindividual Variations in Fecal β-Lactamase Activity Affect the Gut Mycobiota Dynamics in Response to β-Lactam Antibiotics | 1-gen-2022 | Delavy, Margot; Burdet, Charles; Sertour, Natacha; Devente, Savannah; Docquier, Jean-Denis; Grall, Nathalie; Volant, Stevenn; Ghozlane, Amine; Duval, Xavier; Mentré, France; D'Enfert, Christophe; Bougnoux, Marie-Elisabeth | - | |
| 1,2,4-Triazole-3-Thione analogues with a 2-Ethylbenzoic acid at position 4 as VIM-type metallo-β-Lactamase inhibitors | 1-gen-2022 | Verdirosa, Federica; Gavara, Laurent; Sevaille, Laurent; Tassone, Giusy; Corsica, Giuseppina; Legru, Alice; Feller, Georges; Chelini, Giulia; Mercuri, Paola Sandra; Tanfoni, Silvia; Sannio, Filomena; Benvenuti, Manuela; Cerboni, Giulia; De Luca, Filomena; Bouajila, Ezeddine; Vo Hoang, Yen; Licznar-Fajardo, Patricia; Galleni, Moreno; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Hernandez, Jean-François | - |
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