Giant orbital retinoblastoma: a case report

Purpose The authors report a case of giant orbital Retinoblastoma following primary enucleation for intraocular tumor. The presence of worms was documented inside the necrotic tumoral mass. Methods The child was diagnosed with unilateral advanced retinoblastoma at the age of one month and enucleated. Chemotherapy and/or radiotherapy had no been performed. 3 months later a mass started growing in the anophthalmic socket and when the child arrived to our referral center the mass was as big as the child’s head. Complete excision of the mass and exenteration have been performed and the presence of worms has been documented in the necrotic part of tumor. Diagnostic workup included computed tomography (CT) and magnetic resonance (MR) of the head and orbit, bone scintigraphy, lumbar puncture with cell count and examination of the cytocentrifugate and bone marrow aspiration. Results The child died 6 months after. Conclusion We describe an extraordinary case of a giant orbital Retinoblastoma following enucleation.