A series of polyelectrolytes having an additional carboxyl group in the side chain was investigated. The four polymers: poly(N-acryloyl-L-valine) (PAV), poly(N-methacryloyl-L-valine) (PMAV), poly(N-acryloyl-L-leucine) (PAL) and poly(N-methacryloyl-L-leucine) (PMAL) were synthesized by radical polymerization of the corresponding monomers. The protonation of the carboxylate group in the polymer and copolymer showed polyelectrolyte behavior with compact conformation in water due to hydrophobic forces between isopropyl groups.
Casolaro, M., Barbucci, R. (1996). Protonation thermodynamics of multiple-stimuli responsive polymers in drug delivery technology. In 5th World Biomaterials Congress (pp.154-154). Society for biomaterials.
Protonation thermodynamics of multiple-stimuli responsive polymers in drug delivery technology
CASOLARO, MARIO;
1996-01-01
Abstract
A series of polyelectrolytes having an additional carboxyl group in the side chain was investigated. The four polymers: poly(N-acryloyl-L-valine) (PAV), poly(N-methacryloyl-L-valine) (PMAV), poly(N-acryloyl-L-leucine) (PAL) and poly(N-methacryloyl-L-leucine) (PMAL) were synthesized by radical polymerization of the corresponding monomers. The protonation of the carboxylate group in the polymer and copolymer showed polyelectrolyte behavior with compact conformation in water due to hydrophobic forces between isopropyl groups.
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https://hdl.handle.net/11365/34293
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