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The present invention is directed to the use of the expression level of the pro-EPIL gene as a biomarker for the diagnosis of testicular cancer, particurarly a testicular germ cell tumor: the invention also relates to an in vitro method for detecting and/or classifying a testicular cancer in subject comprising a step of determining the expression level of the gene encoding the pro-EPIl peptide in a biological, particularly in combination with the determination of the beta subunit HCGBeta and the human alpha-fetoprotein AFP. The invention is also directed to a kit or solid support comprising nucleic acids or antribodies capable of determinig the presence or the expression level of these three biological markers.

Bellet, D., Pecking, A., Richon, S., Petraglia, F. (2011)Pro-EPILl expression level in a biological sample as testicular cancer biomarker, particularly in combination with the HCBETA and AFP biomarkers. . Brevetto No. US 2011/0105365 A1.

Pro-EPILl expression level in a biological sample as testicular cancer biomarker, particularly in combination with the HCBETA and AFP biomarkers

PETRAGLIA, FELICE
2011-01-01

Abstract

The present invention is directed to the use of the expression level of the pro-EPIL gene as a biomarker for the diagnosis of testicular cancer, particurarly a testicular germ cell tumor: the invention also relates to an in vitro method for detecting and/or classifying a testicular cancer in subject comprising a step of determining the expression level of the gene encoding the pro-EPIl peptide in a biological, particularly in combination with the determination of the beta subunit HCGBeta and the human alpha-fetoprotein AFP. The invention is also directed to a kit or solid support comprising nucleic acids or antribodies capable of determinig the presence or the expression level of these three biological markers.
2011
Bellet, D., Pecking, A., Richon, S., Petraglia, F. (2011)Pro-EPILl expression level in a biological sample as testicular cancer biomarker, particularly in combination with the HCBETA and AFP biomarkers. . Brevetto No. US 2011/0105365 A1.
6.1 Brevetto
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11365/31868
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